Search Results - "Gete, Yantenew G."
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Mechanisms of angiogenic incompetence in Hutchinson–Gilford progeria via downregulation of endothelial NOS
Published in Aging cell (01-07-2021)“…Hutchinson–Gilford progeria syndrome (HGPS) is a rare genetic disorder with features of accelerated aging. The majority of HGPS cases are caused by a de novo…”
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Impaired LEF1 Activation Accelerates iPSC-Derived Keratinocytes Differentiation in Hutchinson-Gilford Progeria Syndrome
Published in International journal of molecular sciences (14-05-2022)“…Hutchinson-Gilford progeria syndrome (HGPS) is a detrimental premature aging disease caused by a point mutation in the human gene. This mutation results in the…”
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In vivo base editing rescues Hutchinson–Gilford progeria syndrome in mice
Published in Nature (London) (28-01-2021)“…Hutchinson–Gilford progeria syndrome (HGPS or progeria) is typically caused by a dominant-negative C•G-to-T•A mutation (c.1824 C>T; p.G608G) in LMNA , the gene…”
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