Search Results - "Gestaut, Matthew M."
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Low Dose Rate Brachytherapy versus Cryotherapy in Low and Intermediate Risk Prostate Cancer
Published in International journal of radiation oncology, biology, physics (01-05-2017)“…Abstract Purpose Cryotherapy and brachytherapy are definitive local treatment options for low- to intermediate-risk prostate cancer. There are both prospective…”
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Inhibition of sphingosine kinase-2 ablates androgen resistant prostate cancer proliferation and survival
Published in Pharmacological reports (01-02-2014)“…Endogenous sphingolipid signaling has been shown to play an important role in prostate cancer endocrine resistance. The novel SphK2 inhibitor, ABC294640, was…”
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3
Single fraction spine stereotactic ablative body radiotherapy with volumetric modulated arc therapy
Published in Journal of neuro-oncology (01-05-2017)“…This study investigated a single institution’s experience with volumetric modulated arc therapy (VMAT) directed stereotactic ablative body radiotherapy (SABR)…”
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Long term clinical toxicity of radiation therapy in prostate cancer patients with Inflammatory Bowel Disease
Published in Reports of practical oncology and radiotherapy (01-01-2017)“…Abstract Aim The study's aim was to examine the clinical impact of radiation therapy (RT) on GI toxicity in Inflammatory Bowel Disease (IBD) patients…”
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Prostate Cancer in Patients With High Prostate-Specific Antigen Levels but Otherwise Very-Low-Risk Disease Behaves Like Prostate Cancer in High-Risk Patients
Published in Clinical genitourinary cancer (01-08-2017)“…Micro-Abstract A review was conducted of divergent-risk prostate cancer patients treated with radiation. These patients exhibited a low-volume, low-risk…”
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Design, Synthesis, and Biological Activity of a Family of Novel Ceramide Analogues in Chemoresistant Breast Cancer Cells
Published in Journal of medicinal chemistry (24-09-2009)“…Resistance to chemotherapy and endocrine therapy is a major cause of breast cancer treatment failure. We have synthesized six novel analogues using C8-ceramide…”
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To B(iopsy) or not to B(iopsy)
Published in Journal of cancer research and therapeutics (01-10-2017)“…Often in metastatic disease, biopsy confirmation of suspicious central nervous system (CNS) lesions is not mandated according to the American College of…”
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Novel d-erythro N-octanoyl sphingosine analogs as chemo- and endocrine-resistant breast cancer therapeutics
Published in Cancer chemotherapy and pharmacology (01-05-2010)“…Purpose Resistance to endocrine and chemotherapies remains the primary cause of breast cancer treatment failure. We have synthesized four novel d-erythro…”
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Abstract 1031: Sphingolipid metabolism as a therapeutic target in chemotherapy resistant and hormone therapy resistant breast cancer
Published in Cancer research (Chicago, Ill.) (15-04-2010)“…Abstract Endocrine- and chemo-resistance are major causes for failure of treatment in recurrent breast cancer. Normal apoptotic pathways targeted by…”
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Abstract 2537: The novel sphingosine kinase inhibitor ABC294640 blocks survival and tumorigenesis in chemo- And endocrine resistant breast cancer
Published in Cancer research (Chicago, Ill.) (15-04-2010)“…Abstract Resistance to chemotherapy is a major cause of breast cancer treatment failure today. The sphingolipid metabolizing enzyme sphingosine kinase converts…”
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11
To B(iopsy) or not to B(iopsy)
Published in Journal of cancer research and therapeutics (01-10-2017)“…Often in metastatic disease, biopsy confirmation of suspicious central nervous system (CNS) lesions is not mandated according to the American College of…”
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