Search Results - "Gessa, G."

Polypharmacy is a risk factor for hospital admission due to a fall: evidence from the English Longitudinal Study of Ageing by Zaninotto, P, Huang, Y T, Di Gessa, G, Abell, J, Lassale, C, Steptoe, A

“…Falls amongst older people are common; however, around 40% of falls could be preventable. Medications are known to increase the risk of falls in older adults…”
Get full text

Psychosexual distress following routine primary human papillomavirus testing: a longitudinal evaluation within the English Cervical Screening Programme by Bennett, KF, Waller, J, McBride, E, Forster, AS, Di Gessa, G, Kitchener, H, Marlow, LAV

“…Objective To assess psychosexual distress over a 12‐month period among women receiving different human papillomavirus (HPV) and cytology results in the context…”
Get full text

The role of stress in the pathophysiology of the dopaminergic system by PANI, L, PORCELLA, A, GESSA, G. L

“…In this review, we will examine the most recent preclinical evidence in support of the fact that both acute and chronic stress may have a detrimental impact on…”
Get full text

Evidence for co-release of noradrenaline and dopamine from noradrenergic neurons in the cerebral cortex by DEVOTO, P, FLORE, G, PANI, L, GESSA, G. L

“…The aim of this study was to determine whether extracellular dopamine (DA) in the prefrontal cortex (PFC) might originate other than from DA neurons, also from…”
Get full text

Paid employment and common mental disorders in 50–64-year olds: analysis of three cross-sectional nationally representative survey samples in 1993, 2000 and 2007 by Perera, G., Di Gessa, G., Corna, L. M., Glaser, K., Stewart, R.

“…Associations between employment status and mental health are well recognised, but evidence is sparse on the relationship between paid employment and mental…”
Get full text

Endocannabinoid system and alcohol addiction: Pharmacological studies by Colombo, Giancarlo, Serra, Salvatore, Vacca, Giovanni, Carai, Mauro A.M., Gessa, Gian Luigi

“…The present paper describes the results of recent pharmacological studies implicating the cannabinoid CB 1 receptor in the neural circuitry regulating alcohol…”
Get full text

Dissociation of Haloperidol, Clozapine, and Olanzapine Effects on Electrical Activity of Mesocortical Dopamine Neurons and Dopamine Release in the Prefrontal Cortex by Gessa, Gian Luigi, Devoto, Paola, Diana, Marco, Flore, Giovanna, Melis, Miriam, Pistis, Marco

“…The aim of the present study was to compare the effects of the typical antipsychotic haloperidol and the atypical antipsychotics clozapine and olanzapine on…”
Get full text

The substituted benzamides and their clinical potential on dysthymia and on the negative symptoms of schizophrenia by PANI, L, GESSA, G. L

“…In this paper the historical and scientific background that led to the use of substituted benzamides in two apparently unrelated clinical conditions namely…”
Get full text

Living alone and mental health: parallel analyses in UK longitudinal population surveys and electronic health records prior to and during the COVID-19 pandemic by McElroy, Eoin, Herrett, Emily, Patel, Kishan, Piehlmaier, Dominik M, Gessa, Giorgio Di, Huggins, Charlotte, Green, Michael J, Kwong, Alex S F, Thompson, Ellen J, Zhu, Jingmin, Mansfield, Kathryn E, Silverwood, Richard J, Mansfield, Rosie, Maddock, Jane, Mathur, Rohini, Costello, Ruth E, Matthews, Anthony, Tazare, John, Henderson, Alasdair, Wing, Kevin, Bridges, Lucy, Bacon, Sebastian, Mehrkar, Amir, Shaw, Richard John, Wels, Jacques, Katikireddi, Srinivasa Vittal, Chaturvedi, Nish, Tomlinson, Laurie A, Patalay, Praveetha

“…BackgroundPeople who live alone experience greater levels of mental illness; however, it is unclear whether the COVID-19 pandemic had a disproportionately…”
Get full text

Effects of Moderate Alcohol Consumption on the Central Nervous System by Eckardt, Michael J., File, Sandra E., Gessa, Gian Luigi, Grant, Kathleen A., Guerri, Consuelo, Hoffman, Paula L., Kalant, Harold, Koob, George F., Li, Ting-Kai, Tabakoff, Boris

“…The concept of moderate consumption of ethanol (beverage alcohol) has evolved over time from considering this level of intake to be nonintoxicating and…”
Get full text

Endocannabinoids Mediate Presynaptic Inhibition of Glutamatergic Transmission in Rat Ventral Tegmental Area Dopamine Neurons through Activation of CB1 Receptors by Melis, Miriam, Pistis, Marco, Perra, Simona, Muntoni, Anna Lisa, Pillolla, Giuliano, Gessa, Gian Luigi

“…The endogenous cannabinoid system has been shown to play a crucial role in controlling neuronal excitability and synaptic transmission. In this study we…”
Get full text

Substance use behaviours and the UK furlough scheme: evidence from eight longitudinal population surveys by Green, M, Di Gessa, G, Maddock, J, Parsons, S, Wielgoszewska, B, Stevenson, AJ, Griffith, GJ, Booth, C, Croft, J, Ploubidis, GB

“…Disruptions to economic activity such as job loss can impact substance use behaviours. During the COVID-19 pandemic many countries implemented a furlough…”
Get full text

Diet, physical activity, and sleep in relation to furlough during the COVID-19 pandemic in the UK: evidence from eight longitudinal studies by Maddock, J, Wielgoszewska, B, Green, MJ, Gessa, G Di, Parsons, S, Griffith, GJ, Croft, J, Stevenson, AJ, Booth, C, Ploubidis, GB

“…The recent Covid-19 pandemic, and its mitigations, are expected to have long-term consequences on the health and health behaviours. In an effort to reduce the…”
Get full text

Mental health inequalities in disruptions across multiple domains during COVID -19: an investigation in 12 population-based longitudinal studies by McElroy, E, Di Gessa, G, Maddock, J, Green, MJ, Thompson, EJ, Davies, HL, Mundy, J, Stevenson, AJ, Kwong, ASF, Patalay, P

“…Disruptions related to the COVID-19 pandemic and its associated virus suppression measures have affected many worldwide but those already suffering from…”
Get full text

Is 2-Hydroxypropyl-β-cyclodextrin a Suitable Carrier for Central Administration of Δ 9 -Tetrahydrocannabinol? Preclinical Evidence by Agabio, R, Sanna, F, Lobina, C, Monduzzi, M, Nairi, V, Cugia, F, Mameli, S, Pisanu, G M, Gessa, G L, Melis, M R

“…Preclinical Research Δ -Tetrahydrocannabinol (THC) is a hydrophobic compound that has a potent antinociceptive effect in animals after intrathecal (IT) or…”
Get full text

Is 2‐Hydroxypropyl‐β‐cyclodextrin a Suitable Carrier for Central Administration of Δ9‐Tetrahydrocannabinol? Preclinical Evidence by Agabio, R., Sanna, F., Lobina, C., Monduzzi, M., Nairi, V., Cugia, F., Mameli, S., Pisanu, G. M., Gessa, G. L., Melis, M. R.

“…ABSTRACT Preclinical Research Δ9‐Tetrahydrocannabinol (THC) is a hydrophobic compound that has a potent antinociceptive effect in animals after intrathecal…”
Get full text

Self-administration of the cannabinoid receptor agonist WIN 55,212-2 in drug-naive mice by Martellotta, M.C., Cossu, G., Fattore, L., Gessa, G.L., Fratta, W.

“…Marijuana is one of the most widely used illicit recreational drugs. However, contrary to the majority of drugs abused by humans, there is a general opinion…”
Get full text

Increase in meso-prefrontal dopaminergic activity after stimulation of CB1 receptors by cannabinoids by Diana, M., Melis, M., Gessa, G. L.

“…The intravenous administration of the psychoactive constituent of marijuana, Δ9‐tetrahydrocannabinol (Δ9‐THC) (62.5–1000 μg/kg), and the synthetic cannabinoid…”
Get full text

Health care disruption inequalities during Covid-19: Evidence from eleven longitudinal studies by Parsons, S, Maddock, J, Di Gessa, G, Green, MJ, Thompson, EJ, Stevenson, AJ, Kwong, ASF, McElroy, E, Silverwood, RJ, Katikireddi, SV

“…Like other health systems worldwide, the UK, the National Health Service (NHS) has faced major disruptions due to high Covid-19 burden and repeated lockdown…”
Get full text

Ability of baclofen in reducing alcohol craving and intake : II-preliminary clinical evidence by ADDOLORATO, G, CAPUTO, F, CAPRISTO, E, COLOMBO, G, GESSA, G. L, GASBARRINI, G

“…Accumulating evidence shows the efficacy of the gamma-aminobutyric acid (GABA(B)) receptor agonist baclofen in reducing alcohol intake in rats, but no studies…”
Get full text