Search Results - "Gerweck, Anu V."

Sex differences in body composition and association with cardiometabolic risk by Schorr, Melanie, Dichtel, Laura E, Gerweck, Anu V, Valera, Ruben D, Torriani, Martin, Miller, Karen K, Bredella, Miriam A

“…Body composition differs between men and women, with women having proportionally more fat mass and men more muscle mass. Although men and women are both…”
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Determinants of bone mineral density in obese premenopausal women by Bredella, Miriam A, Torriani, Martin, Ghomi, Reza Hosseini, Thomas, Bijoy J, Brick, Danielle J, Gerweck, Anu V, Harrington, Lindsey M, Breggia, Anne, Rosen, Clifford J, Miller, Karen K

“…Abstract Despite being a risk factor for cardiovascular disease and diabetes mellitus, obesity has been thought to protect against osteoporosis. However,…”
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Higher serum myostatin levels are associated with lower insulin sensitivity in adults with overweight/obesity by Dichtel, Laura E., Kimball, Allison, Bollinger, Bryan, Scarff, Geetanjali, Gerweck, Anu V., Bredella, Miriam A., Haines, Melanie S.

“…Myostatin inhibition improves insulin sensitivity in preclinical and clinical models; however, studies investigating the relationship between serum myostatin…”
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Vertebral Strength and Estimated Fracture Risk Across the BMI Spectrum in Women by Bachmann, Katherine N, Bruno, Alexander G, Bredella, Miriam A, Schorr, Melanie, Lawson, Elizabeth A, Gill, Corey M, Singhal, Vibha, Meenaghan, Erinne, Gerweck, Anu V, Eddy, Kamryn T, Ebrahimi, Seda, Koman, Stuart L, Greenblatt, James M, Keane, Robert J, Weigel, Thomas, Dechant, Esther, Misra, Madhusmita, Klibanski, Anne, Bouxsein, Mary L, Miller, Karen K

“…ABSTRACT Somewhat paradoxically, fracture risk, which depends on applied loads and bone strength, is elevated in both anorexia nervosa and obesity at certain…”
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Ectopic and serum lipid levels are positively associated with bone marrow fat in obesity by Bredella, Miriam A, Gill, Corey M, Gerweck, Anu V, Landa, Melissa G, Kumar, Vidhya, Daley, Scott M, Torriani, Martin, Miller, Karen K

“…To investigate the associations between ectopic and serum lipid levels and bone marrow fat, as a marker of stem cell differentiation, in young obese men and…”
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Body Composition and Ectopic Lipid Changes With Biochemical Control of Acromegaly by Bredella, Miriam A, Schorr, Melanie, Dichtel, Laura E, Gerweck, Anu V, Young, Brian J, Woodmansee, Whitney W, Swearingen, Brooke, Miller, Karen K

“…Abstract Context Acromegaly is characterized by growth hormone (GH) and insulinlike growth factor-1 (IGF-1) hypersecretion, and GH and IGF-1 play important…”
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Determinants of Bone Microarchitecture and Mechanical Properties in Obese Men by Bredella, Miriam A, Lin, Eleanor, Gerweck, Anu V, Landa, Melissa G, Thomas, Bijoy J, Torriani, Martin, Bouxsein, Mary L, Miller, Karen K

“…Context: Recent studies have suggested that obesity in men is associated with increased fracture risk. Obesity in men is also associated with dysregulation of…”
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Vertebral Bone Marrow Fat Is Positively Associated With Visceral Fat and Inversely Associated With IGF-1 in Obese Women by Bredella, Miriam A., Torriani, Martin, Ghomi, Reza Hosseini, Thomas, Bijoy J., Brick, Danielle J., Gerweck, Anu V., Rosen, Clifford J., Klibanski, Anne, Miller, Karen K.

“…Recent studies have demonstrated an important physiologic link between bone and fat. Bone and fat cells arise from the same mesenchymal precursor cell within…”
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Comparison of DXA and CT in the Assessment of Body Composition in Premenopausal Women With Obesity and Anorexia Nervosa by Bredella, Miriam A., Ghomi, Reza Hosseini, Thomas, Bijoy J., Torriani, Martin, Brick, Danielle J., Gerweck, Anu V., Misra, Madhusmita, Klibanski, Anne, Miller, Karen K.

“…Accurate methods for assessing body composition in subjects with obesity and anorexia nervosa (AN) are important for determination of metabolic and…”
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Impact of GH administration on skeletal endpoints in adults with overweight/obesity by Dichtel, Laura E, Haines, Melanie S, Gerweck, Anu V, Bollinger, Bryan, Kimball, Allison, Schoenfeld, David, Bredella, Miriam A, Miller, Karen K

“…Objective Overweight/obesity is associated with relative growth hormone (GH) deficiency and increased fracture risk. We hypothesized that GH administration…”
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Overweight/Obese Adults With Pituitary Disorders Require Lower Peak Growth Hormone Cutoff Values on Glucagon Stimulation Testing to Avoid Overdiagnosis of Growth Hormone Deficiency by Dichtel, Laura E, Yuen, Kevin C. J, Bredella, Miriam A, Gerweck, Anu V, Russell, Brian M, Riccio, Ariana D, Gurel, Michelle H, Sluss, Patrick M, Biller, Beverly M. K, Miller, Karen K

“…Context: Obesity is associated with diminished GH secretion, which may result in the overdiagnosis of adult GH deficiency (GHD) in overweight/obese pituitary…”
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Bone microarchitecture and estimated bone strength in men with active acromegaly by Silva, Paula P B, Amlashi, Fatemeh G, Yu, Elaine W, Pulaski-Liebert, Karen J, Gerweck, Anu V, Fazeli, Pouneh K, Lawson, Elizabeth, Nachtigall, Lisa B, Biller, Beverly M K, Miller, Karen K, Klibanski, Anne, Bouxsein, Mary, Tritos, Nicholas A

“…Context Both acromegaly and adult growth hormone deficiency (GHD) are associated with increased fracture risk. Sufficient data are lacking regarding cortical…”
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Comparison of Hip Geometry, Strength, and Estimated Fracture Risk in Women With Anorexia Nervosa and Overweight/Obese Women by Bachmann, Katherine Neubecker, Fazeli, Pouneh K, Lawson, Elizabeth A, Russell, Brian M, Riccio, Ariana D, Meenaghan, Erinne, Gerweck, Anu V, Eddy, Kamryn, Holmes, Tara, Goldstein, Mark, Weigel, Thomas, Ebrahimi, Seda, Mickley, Diane, Gleysteen, Suzanne, Bredella, Miriam A, Klibanski, Anne, Miller, Karen K

“…Context: Data suggest that anorexia nervosa (AN) and obesity are complicated by elevated fracture risk, but skeletal site-specific data are lacking…”
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Effects of growth hormone receptor antagonism and somatostatin analog administration on quality of life in acromegaly by Dichtel, Laura E., Kimball, Allison, Yuen, Kevin C. J., Woodmansee, Whitney, Haines, Melanie S., Guan, Qiu Xia, Swearingen, Brooke, Nachtigall, Lisa B., Tritos, Nicholas A., Sharpless, Julie L., Kaiser, Ursula B., Gerweck, Anu V., Miller, Karen K.

“…Objective Acromegaly is associated with impaired quality of life (QoL). We investigated the effects of biochemical control of acromegaly by growth hormone…”
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Association between adiposity and cognitive function in young men: Hormonal mechanisms by Bove, Riley M., Gerweck, Anu V., Mancuso, Sarah M., Bredella, Miriam A., Sherman, Janet C., Miller, Karen K.

“…Objective To determine the association between adiposity, hormones, and cognition in young men with abdominal obesity. Methods In this cross‐sectional…”
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Effects of GH on Body Composition and Cardiovascular Risk Markers in Young Men With Abdominal Obesity by Bredella, Miriam A, Gerweck, Anu V, Lin, Eleanor, Landa, Melissa G, Torriani, Martin, Schoenfeld, David A, Hemphill, Linda C, Miller, Karen K

“…Context: Visceral adiposity is associated with increased cardiometabolic risk and decreased GH secretion. Objective: Our objective was to determine the effects…”
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Effects of growth hormone administration for 6 months on bone turnover and bone marrow fat in obese premenopausal women by Bredella, Miriam A, Gerweck, Anu V, Barber, Lauren A, Breggia, Anne, Rosen, Clifford J, Torriani, Martin, Miller, Karen K

“…Abstract Purpose Abdominal adiposity is associated with low BMD and decreased growth hormone (GH) secretion, an important regulator of bone homeostasis. The…”
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Vertebral Volumetric Bone Density and Strength are Impaired in Women with Low-weight and Atypical Anorexia Nervosa by Bachmann, Katherine N, Schorr, Melanie, Bruno, Alexander G, Bredella, Miriam A, Lawson, Elizabeth A, Gill, Corey M, Singhal, Vibha, Meenaghan, Erinne, Gerweck, Anu V, Slattery, Meghan, Eddy, Kamryn T, Ebrahimi, Seda, Koman, Stuart L, Greenblatt, James M, Keane, Robert J, Weigel, Thomas, Misra, Madhusmita, Bouxsein, Mary L, Klibanski, Anne, Miller, Karen K

“…Context: Areal BMD is lower, particularly at the spine, in low-weight women with anorexia nervosa (AN). However, little is known about vertebral integral…”
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The effect of growth hormone on bioactive IGF in overweight/obese women by Dichtel, Laura E., Bjerre, Mette, Schorr, Melanie, Bredella, Miriam A., Gerweck, Anu V., Russell, Brian M., Frystyk, Jan, Miller, Karen K.

“…Overweight/obesity is characterized by decreased growth hormone (GH) secretion whereas circulating IGF-I levels are less severely reduced. Yet, the activity of…”
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Body composition predictors of skeletal integrity in obesity by Schorr, Melanie, Dichtel, Laura E., Gerweck, Anu V., Torriani, Martin, Miller, Karen K., Bredella, Miriam A.

“…Objective To determine body composition predictors of skeletal integrity in overweight/obese subjects using dual energy X-ray absorptiometry (DXA). We…”
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