Search Results - "Gervois, P"

Effect of isolation methodology on stem cell properties and multilineage differentiation potential of human dental pulp stem cells by Hilkens, P, Gervois, P, Fanton, Y, Vanormelingen, J, Martens, W, Struys, T, Politis, C, Lambrichts, I, Bronckaers, A

“…Dental pulp stem cells (DPSCs) are an attractive alternative mesenchymal stem cell (MSC) source because of their isolation simplicity compared with the more…”
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Pro-angiogenic impact of dental stem cells in vitro and in vivo by Hilkens, P., Fanton, Y., Martens, W., Gervois, P., Struys, T., Politis, C., Lambrichts, I., Bronckaers, A.

“…Within the field of dental tissue engineering, the establishment of adequate tissue vascularization is one of the most important burdens to overcome. As…”
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Paracrine Maturation and Migration of SH-SY5Y Cells by Dental Pulp Stem Cells by Gervois, P., Wolfs, E., Dillen, Y., Hilkens, P., Ratajczak, J., Driesen, R.B., Vangansewinkel, T., Bronckaers, A., Brône, B., Struys, T., Lambrichts, I.

“…Neurological disorders are characterized by neurodegeneration and/or loss of neuronal function, which cannot be adequately repaired by the host. Therefore,…”
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Magnetic resonance imaging of human dental pulp stem cells in vitro and in vivo by Struys, T, Ketkar-Atre, A, Gervois, P, Leten, C, Hilkens, P, Martens, W, Bronckaers, A, Dresselaers, T, Politis, C, Lambrichts, I, Himmelreich, U

“…Recent advances in stem cell research have shown the promising nature of mesenchymal stem cells as plausible candidates for cell-based regenerative medicine…”
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Induction of IκBα Expression as a Mechanism Contributing to the Anti-inflammatory Activities of Peroxisome Proliferator-activated Receptor-α Activators by Gervois, Philippe, Fruchart, Jean-Charles, Delerive, Philippe, Staels, Bart

“…Chronic inflammation is a hallmark of degenerative diseases such as atherosclerosis. Peroxisome proliferator-activated receptors (PPARs) are transcription…”
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Fibrates down-regulate IL-1–stimulated C-reactive protein gene expression in hepatocytes by reducing nuclear p50-NFκB–C/EBP-β complex formation by Kleemann, Robert, Gervois, Philippe P., Verschuren, Lars, Staels, Bart, Princen, Hans M.G., Kooistra, Teake

“…C-reactive protein (CRP) is a major acute-phase protein in humans. Elevated plasma CRP levels are a risk factor for cardiovascular disease. CRP is…”
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Fibrates Suppress Bile Acid Synthesis via Peroxisome Proliferator–Activated Receptor-α–Mediated Downregulation of Cholesterol 7α-Hydroxylase and Sterol 27-Hydroxylase Expression by Post, Sabine M, Duez, Hélène, Gervois, Philippe P, Staels, Bart, Kuipers, Folkert, Princen, Hans M.G

“…Fibrates are hypolipidemic drugs that affect the expression of genes involved in lipid metabolism by activating peroxisome proliferator–activated receptors…”
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Fibrates Suppress Fibrinogen Gene Expression in Rodents Via Activation of the Peroxisome Proliferator-Activated Receptor-α by Kockx, Maaike, Gervois, Philippe P., Poulain, Philippe, Derudas, Bruno, Peters, Jeffrey M., Gonzalez, Frank J., Princen, Hans M.G., Kooistra, Teake, Staels, Bart

“…Plasma fibrinogen levels have been identified as an important risk factor for cardiovascular diseases. Among the few compounds known to lower circulating…”
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Retinoids increase human apo C-III expression at the transcriptional level via the retinoid X receptor. Contribution to the hypertriglyceridemic action of retinoids by Vu-Dac, N, Gervois, P, Torra, I P, Fruchart, J C, Kosykh, V, Kooistra, T, Princen, H M, Dallongeville, J, Staels, B

“…Hypertriglyceridemia is a metabolic complication of retinoid therapy. In this study, we analyzed whether retinoids increase the expression of apo C-III, an…”
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Fibrates Increase Human REV-ERB  Expression in Liver via a Novel Peroxisome Proliferator-Activated Receptor Response Element by Gervois, P.

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Stearoyl-CoA desaturase-1 impairs the reparative properties of macrophages and microglia in the brain by Bogie, Jeroen F J, Grajchen, Elien, Wouters, Elien, Corrales, Aida Garcia, Dierckx, Tess, Vanherle, Sam, Mailleux, Jo, Gervois, Pascal, Wolfs, Esther, Dehairs, Jonas, Van Broeckhoven, Jana, Bowman, Andrew P, Lambrichts, Ivo, Gustafsson, Jan-Åke, Remaley, Alan T, Mulder, Monique, Swinnen, Johannes V, Haidar, Mansour, Ellis, Shane R, Ntambi, James M, Zelcer, Noam, Hendriks, Jerome J A

“…Failure of remyelination underlies the progressive nature of demyelinating diseases such as multiple sclerosis. Macrophages and microglia are crucially…”
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Modulation of Hepatic Inflammatory Risk Markers of Cardiovascular Diseases by PPAR–α Activators: Clinical and Experimental Evidence by Zambon, Alberto, Gervois, Philippe, Pauletto, Paolo, Fruchart, Jean-Charles, Staels, Bart

“…Atherosclerosis is a long-term chronic inflammatory disease associated with increased concentrations of inflammatory hepatic markers, such as CRP and…”
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Global Suppression of IL-6-induced Acute Phase Response Gene Expression after Chronic in Vivo Treatment with the Peroxisome Proliferator-activated Receptor-α Activator Fenofibrate by Gervois, Philippe, Kleemann, Robert, Pilon, Antoine, Percevault, Frédéric, Koenig, Wolfgang, Staels, Bart, Kooistra, Teake

“…The peroxisome proliferator-activated receptor α (PPARα), which is highly expressed in liver, plays key roles in lipid metabolism and inflammation…”
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Angiogenic Capacity of Periodontal Ligament Stem Cells Pretreated with Deferoxamine and/or Fibroblast Growth Factor-2 by Ratajczak, Jessica, Hilkens, Petra, Gervois, Pascal, Wolfs, Esther, Jacobs, Reinhilde, Lambrichts, Ivo, Bronckaers, Annelies

“…Periodontal ligament stem cells (PDLSCs) represent a good source of multipotent cells for cell-based therapies in regenerative medicine. The success rate of…”
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The Orphan Nuclear Receptor Rev-Erbα Is a Peroxisome Proliferator-activated Receptor (PPAR) γ Target Gene and Promotes PPARγ-induced Adipocyte Differentiation by Fontaine, Coralie, Dubois, Guillaume, Duguay, Yannick, Helledie, Torben, Vu-Dac, Ngoc, Gervois, Philippe, Soncin, Fabrice, Mandrup, Susanne, Fruchart, Jean-Charles, Fruchart-Najib, Jamila, Staels, Bart

“…Rev-Erbα (NR1D1) is an orphan nuclear receptor encoded on the opposite strand of the thyroid receptor α gene. Rev-Erbα mRNA is induced during adipocyte…”
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Peroxisome Proliferator-activated Receptor α Activators Improve Insulin Sensitivity and Reduce Adiposity by Guerre-Millo, Michèle, Gervois, Philippe, Raspé, Eric, Madsen, Lise, Poulain, Philippe, Derudas, Bruno, Herbert, Jean-Marc, Winegar, Deborah A., Willson, Timothy M., Fruchart, Jean-Charles, Berge, Rolf K., Staels, Bart

“…Fibrates and glitazones are two classes of drugs currently used in the treatment of dyslipidemia and insulin resistance (IR), respectively. Whereas glitazones…”
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Apolipoprotein A5, a crucial determinant of plasma triglyceride levels, is highly responsive to peroxisome proliferator-activated receptor alpha activators by Vu-Dac, Ngoc, Gervois, Philippe, Jakel, Heidi, Nowak, Maxime, Bauge, Eric, Dehondt, Helene, Staels, Bart, Pennacchio, Len A, Rubin, Edward M, Fruchart-Najib, Jamila, Fruchart, Jean-Charles

“…The recently discovered APOA5 gene has been shown in humans and mice to be important in determining plasma triglyceride levels, a major cardiovascular disease…”
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Peroxisome proliferator-activated receptor alpha in metabolic disease, inflammation, atherosclerosis and aging by Pineda Torra, I, Gervois, P, Staels, B

“…Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors which are activated by fatty acids and derivatives. The PPAR alpha form has been…”
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Negative Regulation of Human Fibrinogen Gene Expression by Peroxisome Proliferator-activated Receptor α Agonists via Inhibition of CCAAT Box/Enhancer-binding Protein β by Gervois, Philippe, Vu-Dac, Ngoc, Kleemann, Robert, Kockx, Maaike, Dubois, Guillaume, Laine, Bernard, Kosykh, Vladimir, Fruchart, Jean-Charles, Kooistra, Teake, Staels, Bart

“…Fibrinogen is a coagulation factor and an acute phase reactant up-regulated by inflammatory cytokines, such as interleukin 6 (IL-6). Elevated plasma fibrinogen…”
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The Nuclear Receptors Peroxisome Proliferator-activated Receptor α and Rev-erbα Mediate the Species-specific Regulation of Apolipoprotein A-I Expression by Fibrates by Vu-Dac, Ngoc, Chopin-Delannoy, Sandrine, Gervois, Philippe, Bonnelye, Edith, Martin, Geneviève, Fruchart, Jean-Charles, Laudet, Vincent, Staels, Bart

“…Fibrates are widely used hypolipidemic drugs which activate the nuclear peroxisome proliferator-activated receptor (PPAR) α and thereby alter the transcription…”
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