Search Results - "Gervin, Joshua"
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1
Leveraging gene correlations in single cell transcriptomic data
Published in BMC bioinformatics (18-09-2024)“…Many approaches have been developed to overcome technical noise in single cell RNA-sequencing (scRNAseq). As researchers dig deeper into data-looking for rare…”
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Journal Article -
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Survival of the Curviest: Noise-Driven Selection for Synergistic Epistasis
Published in PLoS genetics (28-04-2016)“…A major goal of human genetics is to elucidate the genetic architecture of human disease, with the goal of fueling improvements in diagnosis and the…”
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Journal Article -
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Discovering regulatory motifs in the Plasmodium genome using comparative genomics
Published in Bioinformatics (01-09-2008)“…Motivation: Understanding gene regulation in Plasmodium, the causative agent of malaria, is an important step in deciphering its complex life cycle as well as…”
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Journal Article -
4
Evolution of Synergistic Epistasis Underlying Complex Disease in Biologically-based Models
Published 01-01-2017“…The origins of complex, heritable traits -- such as familial risk for cancer, diabetes, and neuropsychiatric illness -- are poorly understood. For the past…”
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Dissertation