Search Results - "Gervay, J"
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P19-15. Synthesis of multivalent mimotopes as potential vaccine candidates
Published in Retrovirology (22-10-2009)Get full text
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Glycosyl iodides are highly efficient donors under neutral conditions
Published in Carbohydrate research (20-07-1999)“…Glycosyl iodides have been prepared and subjected to glycosylation under neutral conditions. The reactions are highly efficient, giving α glycosides even with…”
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Cell wall glycosphingolipids of Sphingomonas paucimobilis are CD1d‐specific ligands for NKT cells
Published in European journal of immunology (01-06-2005)“…The current consensus on characterization of NKT cells is based on their reactivity to the synthetic glycolipid, α‐galactosylceramide (α‐GalCer) in a…”
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Studies on the synthesis of C-Glycoside sulfones as potential glycosyl transferase inhibitors
Published in Tetrahedron (01-12-1997)“…β- C-Glycoside sulfoxides and sulfones were prepared by radical addition of thiol acetic acid to exocyclic glycals followed by deacetylation, S-alkylation, and…”
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Efficient Synthesis of α-Galactosyl Ceramide Analogues Using Glycosyl Iodide Donors
Published in Organic letters (12-05-2005)“…The combination of reactive galactosyl iodide donors with electron-rich acceptor lipids provides highly stereoselective and efficient routes to α GalCer…”
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Mechanistic studies on the stereoselective formation of glycosyl iodides: first characterization of β- d-glycosyl iodides
Published in Carbohydrate research (12-05-1997)“…Treatment of glycosyl acetates with one equivalent of iodotrimethylsilane at low temperature results in the quantitative formation of glycosyl iodides…”
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Utilization of ELISA technology to measure biological activities of carbohydrates relevant in disease status
Published in Current medicinal chemistry (01-02-1999)“…Since its discovery in 1960, ELISA technology has been utilized in an increasing number of biological and biochemical investigations. It has proven to be one…”
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Perspectives from a newly begun career
Published in Journal of chemical education (01-12-1998)“…[...]this issue was examined 75 years ago at the Journal's inception. Furthermore, we have yet to establish what fundamental level of understanding is required…”
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Solution phase synthesis of (1→5)-amide linked sugar amino acid dimers derived from sialic acids
Published in Tetrahedron letters (03-03-1997)“…Carboxy-protected amino derivatives and amino-protected carboxy derivatives of three different C-2 analogs as well as a 2,3-dehydro NeuAc were prepared. These…”
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Efficient Route to 2-Deoxy β-O-Aryl-d-Glycosides via Direct Displacement of Glycosyl Iodides
Published in Organic letters (30-10-2003)“…The conversion of glycals to 2-deoxy glycosyl acetates followed by reaction with trimethylsilyl iodide affords the corresponding glycosyl iodides, which…”
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Temperature Dependence of Molecular Conformation, Dynamics, and Chemical Shift Anisotropy of α,α-Trehalose in D2O by NMR Relaxation
Published in Journal of the American Chemical Society (12-02-1997)“…A molecular dynamics study and solution-phase 1H and 13C chemical shift anisotropy determination of a symmetric cryogenic disaccharide, α,α-trehalose, has been…”
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A stereospecific route to 2-deoxy-.beta.-glycosides
Published in Journal of organic chemistry (01-08-1991)Get full text
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Synthesis of Oligomers Derived from Amide-Linked Neuraminic Acid Analogues
Published in Journal of organic chemistry (20-02-2004)“…N-Fluoren-9-ylmethoxycarbonyl-protected sugar amino acids derived from α-O-methoxy- and 2,3-dehydroneuraminic acids have been prepared. Incorporation of these…”
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Ring opening of sialyllactones with glycine esters: Synthesis of selectively protected glycinyl-NeuAc saccharopeptides
Published in Tetrahedron (11-08-1997)“…Two different classes of sialyllactones were prepared as potential substrates for ring opening reactions with naturally occurring amino acids. The…”
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HI/acetic acid reduction of peracetylated N-acetyl neuraminic acid esters to stereoselectively provide α-2-deoxy-2-hydrido derivatives
Published in Tetrahedron letters (01-08-1997)“…Peracetylated ester derivatives of N-acetyl neuraminic acid were reacted with hydrogen iodide in acetic acid to stereoselectively provide α-2-deoxy-2-hydrido…”
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Virus-Induced Inhibition of CD1d1-Mediated Antigen Presentation: Reciprocal Regulation by p38 and ERK
Published in Journal of Immunology (01-10-2005)“…A critical component of the host's innate immune response involves lipid Ag presentation by CD1d molecules to NK T cells. In this study we used murine…”
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Efficient Syntheses of β-Cyanosugars Using Glycosyl Iodides Derived from Per-O-silylated Mono- and Disaccharides
Published in Organic letters (28-06-2001)“…Reported herein is a general method for the efficient syntheses of a variety of β-cyano glycosides through the activation of per-O-trimethylsilyl glycosides…”
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Solution- and solid-phase oligosaccharide synthesis using glucosyl iodides: a comparative study
Published in Carbohydrate research (19-11-2002)“…Glycosyl iodide donors have been used in both solid- and solution-phase syntheses yielding α-(1→6)-linked glucosyl oligomers in highly efficient protocols…”
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