Search Results - "Gervas, P A"

DNA methylome analysis reveals potential alterations contributing to the progression of bronchial hyperplasia by Ponomaryova, A. A., Schegoleva, A. A., Gervas, P. A., Pancova, O. V., Gerashchenko, T. S., Zarubin, A. A., Perelmuter, V. M., Cherdyntseva, N. V., Denisov, E. V.

“…Background Squamous cell lung cancer (SCLC) arises from bronchial changes: basal cell hyperplasia (BCH), squamous metaplasia (SM), and dysplasia. However, the…”
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Analysis of Methylome of Different Forms of Basal Cell Hyperplasia and Squamous Cell Metaplasia of Bronchial Epithelium by Ponomaroyva, A. A., Schegoleva, A. A., Gervas, P. A., Gerashchenko, T. S., Pankova, O. V., Ershov, N. I., Perelmuter, V. M., Cherdyntseva, N. V., Denisov, E. V.

“…Squamous cell lung cancer (SCLC) occurs as a result of dysregenerative changes in the bronchial epithelium: basal cell hyperplasia (BCH), squamous cell…”
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Endogenous and exogenous risk factors affecting the incidence of breast cancer in the population of Yakutia by Tikhonov, D. G., Molokov, A. Yu, Belyavskaya, V. A., Ananina, O. A., Gervas, P. A.

“…The purpose of the study : to analyze the breast cancer incidence and breast cancer risk factors for the population of the Republic of Sakha (Yakutia) in…”
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Variability of the mitochondrial genome in young Yakut patients with breast cancer by Tikhonov, D. G., Egorov, A. N., Golubenko, M. V., Molokov, A. Yu, Belyavskaya, V. A., Gervas, P. A., Skryabin, N. A.

“…Background . The Sakha (Yakutia) population, the indigenous population of Siberia living in Yakutia, has one of the lowest rates of breast cancer (BC)…”
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Circulating tumor cells in breast cancer: functional heterogeneity, pathogenetic and clinical aspects by Cherdyntseva, N V, Litviakov, N V, Denisov, E V, Gervas, P A, Cherdyntsev, E S

“…Each patient has a unique history of cancer ecosystem development, resulting in intratumor heterogeneity. In order to effectively kill the tumor cells by…”
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Nivolumab monotherapy in metastatic colorectal cancer: current approaches to response evaluation by Babyshkina, N. N., Dronova, T. A., Gervas, P. A., Popova, N. O., Dobrodeev, A. Yu, Kostromitsky, D. N., Afanasyev, S. G., Goldberg, V. E., Cherdyntseva, N. V.

“…Aim of the study: a systematic analysis of the modern literature data on the nivolumab monotherapy efficacy in patients with metastatic colorectal cancer…”
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New mutation of the TP53 gene associated with the hereditary breast cancer in a young Tuvinian woman by Gervas, P. A., Molokov, A. Yu, Zarubin, A. A., Ponomareva, A. A., Babyshkina, N. N., Belyavskaya, V. A., Pisareva, L. F., Choynzonov, E. L., Cherdyntseva, N. V.

“…Background. The identification of the ethnospecific mutations associated with hereditary breast cancer remains challenging. Next generation sequencing (Ngs)…”
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Ethnic aspects of hereditary breast cancer by Gervas, P. A., Molokov, A. Yu, Panpherova, E. V., Pisareva, L. Ph, Cherdyntseva, N. V.

“…This study aimed to reveal the spectrum of BRca1 and BRca2 genes mutation in various ethnic groups of the Russian Federation. asystematic literature search…”
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Age-related function of tumor suppressor gene TP53:contribution to cancer risk and progression by Cherdyntseva, N V, Gervas, P A, Litvyakov, N V, Stakcheeva, M N, Ponomaryeva, A A, Dobrodeev, A Yu, Denisov, E V, Belyavskaya, V A, Choinzonov, E L

“…To examine the influence of combined genotypes of TP53 (exon 4, intron 3, intron 6) and XRCC1 (codon 10) on lung cancer age of onset. TP53 polymorphisms in…”
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Genetic status of p53 in stomach cancer: somatic mutations and polymorphism of codon 72 by Belyavskaya, V A, Vardosanidze, V K, Smirnova, O Yu, Karakin, E I, Savkin, I V, Gervas, P A, Cherdyntseva, N V, Voevoda, M I

“…The incidence of somatic mutagenesis of p53 oncosuppressor protein in malignant tumors of the stomach and genetic polymorphism of p53 were studied in patients…”
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Polymorphism of chemokine receptor gene CCR5 in multiple sclerosis patients and in healthy subjects in the Siberian region by Yu. Yu. Orlova, V. M. Alifirova, N. V. Cherdyntseva, P. A. Gervas

“…Multiple sclerosis is chronic inflammatory disease of the central nervous system in the development of which chemokines of the type Tx1 play the leading role…”
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Whole exome sequencing: the search for mutations associated with hereditary breast cancer in ethnic groups of Siberia by Gervas, P. A., Molokov, A. Yu, Babyshkina, N. N., Ivanova, F. G., Nikolaeva, T. I., Tikhonov, D. G., Choynzonov, E. L., Cherdyntseva, N. V.

“…Hereditary breast cancer (HBC) is a heterogeneous disease caused by mutations in genes characterized by ethnic specifcity. The clinical heterogeneity of this…”
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The activity of superoxide dismutase and glutathione peroxidase and the level of malonic dialdehyde in prematures with hypoxic disorders of the central nervous system by zhelev, V A, Filippov, G P, Smirnova, L P, Serebrov, V Iu, Gervas, P A, Mikhalev, E V, Ermolenko, S P, Gorev, V V

“…The activity of superoxide dismutase and glutathione peroxidase and the level of malonic dialdehyde were studied 53 prematures with hypoxia of the central…”
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A novel germline mutation of the PALB gene in a young Yakut breast cancer woman by Gervas, P. A., Molokov, A. Yu, Zarubin, A. A., Ivanova, A. A., Tikhonov, D. G., Kipriyanova, N. S., Egorov, A. N., Zhuikova, L. D., Shefer, N. A., Topolnitskiy, E. B., Belyavskaya, V. A., Pisareva, L. F., Choynzonov, E. L., Cherdyntseva, N. V.

“…Background . Breast cancer (BC) is the most common female malignancy worldwide. partner and localizer of BRCA2 gene ( PALB2 ) is directly involved in DNA…”
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A novel germline mutation of the PALB2 gene in a young Yakut breast cancer woman by P. A. Gervas, A. Yu. Molokov, A. A. Zarubin, A. A. Ivanova, D. G. Tikhonov, N. S. Kipriyanova, A. N. Egorov, L. D. Zhuikova, N. A. Shefer, E. B. Topolnitskiy, V. A. Belyavskaya, L. F. Pisareva, E. L. Choynzonov, N. V. Cherdyntseva

“…Background. Breast cancer (BC) is the most common female malignancy worldwide. Partner And Localizer of BRCA2 gene (PALB2) is directly involved in DNA damage…”
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MONITORING OF EGFR MUTATIONS IN THE CIRCULATING TUMOR DNA FROM BLOOD PLASMA OF PATIENTS WITH NON-SMALL CELL LUNG CANCER by Shamanin, V. A., Karpov, I. V., Gervas, P. А., Cherdyntseva, N. V., Simolina, E. I., Kozlov, V. V., Kovalenko, S. P.

“…Activating mutations of EGFR are associated with sensitivity of non-small cell lung cancer (NSCLC ) to tyrosine kinase inhibitors (TKI). Liquid biopsy using…”
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PROBLEM AND PERSPECTIVE TO IMPROVE MOLECULAR TESTING TO CHOOSE APPROPRIATE TARGET THERAPY by P. A. Gervas, N. V. Litviakov, N. O. Popova, A. Yu. Dobrodeev, A. S. Tarasova, E. L. Yumov, F. G. Ivanova, O. V. Cheremisina, S. G. Afanasyev, V. E. Goldberg, N. V. Cherdyntseva

“…In the last decade, molecularly-targeted therapy is the most intensively developing treatment modalities in oncology. The main targets for this therapy are…”
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Ethnic aspects of hereditary breast cancer in the region of Siberia by Cherdyntseva, N V, Pisareva, L F, Ivanova, A A, Panferova, Ye V, Malinovskaya, E A, Odintsova, I N, Doroshenko, A V, Gervas, P A, Slonimskaya, E M, Shivit-ool, A A, Dvornichenko, V V, Choinzonov, Ye L

“…Ethnic diversity of the population in the region of Siberia suggests the existence of different germline mutations in the BRCA1/2 genes associated with breast…”
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