Search Results - "Gerson, D"

Potential and Challenges for the Clinical Use of d-Serine As a Cognitive Enhancer by Guercio, Gerson D, Panizzutti, Rogerio

“…After 25 years of its discovery in the rat brain, d-serine is a recognized modulator of synaptic plasticity and cognitive processes through its actions on the…”
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Interfilament interaction between IMPDH and CTPS cytoophidia by Chang, Chia‐Chun, Keppeke, Gerson D., Sung, Li‐Ying, Liu, Ji‐Long

“…Inosine monophosphate dehydrogenase (IMPDH) and cytidine triphosphate synthase (CTPS) are two metabolic enzymes that perform rate‐limiting steps in the de novo…”
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Allopregnanolone: Regenerative therapeutic to restore neurological health by Hernandez, Gerson D., Brinton, Roberta D.

“…Chronic stress has been proposed as a driver of altered brain structure and function, including the pathogenesis of neurodegenerative diseases and a driver of…”
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The IMPDH cytoophidium couples metabolism and fetal development in mice by Peng, Min, Keppeke, Gerson D., Tsai, Li-Kuang, Chang, Chia-Chun, Liu, Ji-Long, Sung, Li-Ying

“…The cytoophidium is an evolutionarily conserved subcellular structure formed by filamentous polymers of metabolic enzymes. In vertebrates, inosine…”
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Dysregulation of auditory neuroplasticity in schizophrenia by Voss, Patrice, Thomas, Maryse E., Guercio, Gerson D., de Villers-Sidani, Etienne

“…Schizophrenia is a complex brain syndrome characterized by an array of positive symptoms (delusions, hallucinations, disorganized speech), negative symptoms…”
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Gardnerella vaginalis alters cervicovaginal epithelial cell function through microbe-specific immune responses by Anton, Lauren, Ferguson, Briana, Friedman, Elliot S, Gerson, Kristin D, Brown, Amy G, Elovitz, Michal A

“…The cervicovaginal (CV) microbiome is highly associated with vaginal health and disease in both pregnant and nonpregnant individuals. An overabundance of…”
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A non-optimal cervicovaginal microbiota in pregnancy is associated with a distinct metabolomic signature among non-Hispanic Black individuals by Gerson, Kristin D., Liao, Jingqiu, McCarthy, Clare, Burris, Heather H., Korem, Tal, Levy, Maayan, Ravel, Jacques, Elovitz, Michal A.

“…Biomechanical and molecular processes of premature cervical remodeling preceding spontaneous preterm birth (sPTB) likely result from interactions between the…”
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Evidence of Hyperacusis in Adult Rats Following Non-traumatic Sound Exposure by Thomas, Maryse E., Guercio, Gerson D., Drudik, Kristina M., de Villers-Sidani, Étienne

“…Manipulations that enhance neuroplasticity may inadvertently create opportunities for maladaptation. We have previously used passive exposures to non-traumatic…”
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Anti-rods/rings: a human model of drug-induced autoantibody generation by Calise, S John, Keppeke, Gerson D, Andrade, Luis E C, Chan, Edward K L

“…In recent years, autoantibodies targeting subcellular structures described as the rods and rings pattern in HEp-2 ANA have been presented as a unique case of…”
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Nasal Administration of Anti-CD3 Monoclonal Antibody (Foralumab) Reduces Lung Inflammation and Blood Inflammatory Biomarkers in Mild to Moderate COVID-19 Patients: A Pilot Study by Moreira, Thais G, Matos, Kimble T F, De Paula, Giovana S, Santana, Thais M M, Da Mata, Raquel G, Pansera, Fernando C, Cortina, Andre S, Spinola, Marcelle G, Baecher-Allan, Clare M, Keppeke, Gerson D, Jacob, Jules, Palejwala, Vaseem, Chen, Karen, Izzy, Saef, Healey, Brian C, Rezende, Rafael M, Dedivitis, Rogerio A, Shailubhai, Kunwar, Weiner, Howard L

“…Immune hyperactivity is an important contributing factor to the morbidity and mortality of COVID-19 infection. Nasal administration of anti-CD3 monoclonal…”
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Effects of Fish Oil on Biomarkers of Axonal Injury and Inflammation in American Football Players: A Placebo-Controlled Randomized Controlled Trial by Mullins, Veronica A, Graham, Sarah, Cummings, Danielle, Wood, Alva, Ovando, Vanessa, Skulas-Ray, Ann C, Polian, Dennis, Wang, Yiwei, Hernandez, Gerson D, Lopez, Claudia M, Raikes, Adam C, Brinton, Roberta D, Chilton, Floyd H

“…There are limited studies on neuroprotection from repeated subconcussive head impacts (RSHI) following docosahexaenoic acid (DHA) + eicosapentaenoic acid (EPA)…”
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Effects of docosahexaenoic acid and eicosapentaoic acid supplementation on white matter integrity after repetitive sub-concussive head impacts during American football: Exploratory neuroimaging findings from a pilot RCT by Raikes, Adam C, Hernandez, Gerson D, Mullins, Veronica A, Wang, Yiwei, Lopez, Claudia, Killgore, William D S, Chilton, Floyd H, Brinton, Roberta D

“…Repetitive sub-concussive head impacts (RSHIs) are common in American football and result in changes to the microstructural integrity of white matter. Both…”
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Exploratory imaging outcomes of a phase 1b/2a clinical trial of allopregnanolone as a regenerative therapeutic for Alzheimer's disease: Structural effects and functional connectivity outcomes by Raikes, Adam C., Hernandez, Gerson D., Matthews, Dawn C., Lukic, Ana S., Law, Meng, Shi, Yonggang, Schneider, Lon S., Brinton, Roberta D.

“…Introduction Allopregnanolone (ALLO), an endogenous neurosteroid, promoted neurogenesis and oligogenesis and restored cognitive function in animal models of…”
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Serum Myostatin and Follistatin Levels in Patients With Dermatomyositis and Polymyositis by de Sordi, Cintia M., dos Reis-Neto, Edgard T., Keppeke, Gerson D., Shinjo, Samuel K., Sato, Emília Inoue

“…Myostatin is a protein in the TGF-β family that negatively regulates muscle mass, and follistatin is a myostatin antagonist. The aim of this study was to…”
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IMP dehydrogenase rod/ring structures in acral melanomas by Keppeke, Gerson D., Barcelos, Denise, Fernandes, Mariana, Comodo, Andréia N., Guimarães, Daiane P., Cardili, Leonardo, Carapeto, Fernando C. L., Andrade, Luis E. C., Landman, Gilles

“…Acral lentiginous melanoma (ALM) is a rare subtype of melanoma with aggressive behavior. IMPDH enzyme, involved in de novo GTP biosynthesis, has been reported…”
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Auditory cognitive training improves prepulse inhibition in serine racemase mutant mice by Guercio, Gerson D., Anjos-Travassos, Yuri, Rangel, Igor, Costa, Stella, Poleto, André, Costa, Deborah, Chaiben, Rafaela, de Villers-Sidani, Etienne, Panizzutti, Rogério

“…Evidence indicates that neuroplasticity-based cognitive training can improve cognition in patients with schizophrenia, but the individual response to training…”
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Corrigendum: Nasal Administration of Anti-CD3 Monoclonal Antibody (Foralumab) Reduces Lung Inflammation and Blood Inflammatory Biomarkers in Mild to Moderate COVID-19 Patients: A Pilot Study by Moreira, Thais G, Matos, Kimble T F, De Paula, Giovana S, Santana, Thais M M, Da Mata, Raquel G, Pansera, Fernando C, Cortina, Andre S, Spinola, Marcelle G, Baecher-Allan, Clare M, Keppeke, Gerson D, Jacob, Jules, Palejwala, Vaseem, Chen, Karen, Izzy, Saef, Healey, Brian C, Rezende, Rafael M, Dedivitis, Rogerio A, Shailubhai, Kunwar, Weiner, Howard L

“…[This corrects the article DOI: 10.3389/fimmu.2021.709861.]…”
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Recipes for the linear analysis of EEG by Parra, Lucas C., Spence, Clay D., Gerson, Adam D., Sajda, Paul

“…In this paper, we describe a simple set of “recipes” for the analysis of high spatial density EEG. We focus on a linear integration of multiple channels for…”
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Safety, tolerability, and pharmacokinetics of allopregnanolone as a regenerative therapeutic for Alzheimer's disease: A single and multiple ascending dose phase 1b/2a clinical trial by Hernandez, Gerson D., Solinsky, Christine M., Mack, Wendy J., Kono, Naoko, Rodgers, Kathleen E., Wu, Chun‐Yi, Mollo, Ana R., Lopez, Claudia M., Pawluczyk, Sonia, Bauer, Gerhard, Matthews, Dawn, Shi, Yonggang, Law, Meng, Rogawski, Michael A., Schneider, Lon S., Brinton, Roberta D.

“…Introduction Allopregnanolone is an endogenous neurosteroid with the potential to be a novel regenerative therapeutic for Alzheimer's disease (AD). Foundations…”
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Comparing quality of reporting between preprints and peer-reviewed articles in the biomedical literature by Carneiro, Clarissa F D, Queiroz, Victor G S, Moulin, Thiago C, Carvalho, Carlos A M, Haas, Clarissa B, Rayêe, Danielle, Henshall, David E, De-Souza, Evandro A, Amorim, Felippe E, Boos, Flávia Z, Guercio, Gerson D, Costa, Igor R, Hajdu, Karina L, van Egmond, Lieve, Modrák, Martin, Tan, Pedro B, Abdill, Richard J, Burgess, Steven J, Guerra, Sylvia F S, Bortoluzzi, Vanessa T, Amaral, Olavo B

“…Preprint usage is growing rapidly in the life sciences; however, questions remain on the relative quality of preprints when compared to published articles. An…”
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