Search Results - "Gerrin, Sean"

SOX9 drives WNT pathway activation in prostate cancer by Ma, Fen, Ye, Huihui, He, Housheng Hansen, Gerrin, Sean J, Chen, Sen, Tanenbaum, Benjamin A, Cai, Changmeng, Sowalsky, Adam G, He, Lingfeng, Wang, Hongyun, Balk, Steven P, Yuan, Xin

“…The transcription factor SOX9 is critical for prostate development, and dysregulation of SOX9 is implicated in prostate cancer (PCa). However, the…”
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Gleason Score 7 Prostate Cancers Emerge through Branched Evolution of Clonal Gleason Pattern 3 and 4 by Sowalsky, Adam G, Kissick, Haydn T, Gerrin, Sean J, Schaefer, Rachel J, Xia, Zheng, Russo, Joshua W, Arredouani, M Simo, Bubley, Glenn J, Sanda, Martin G, Li, Wei, Ye, Huihui, Balk, Steven P

“…The molecular features that account for the distinct histology and aggressive biological behavior of Gleason pattern 4 (Gp4) versus Gp3 prostate cancer, and…”
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Mutation Profiling Indicates High Grade Prostatic Intraepithelial Neoplasia as Distant Precursors of Adjacent Invasive Prostatic Adenocarcinoma by Gerrin, Sean J., Sowalsky, Adam G., Balk, Steven P., Ye, Huihui

“…INTRODUCTION High Grade Prostatic Intraepithelial Neoplasia (HGPIN) is the putative precursor lesion to prostatic adenocarcinoma (PCa), but the precise…”
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Gleason Misclassification Rate Is Independent of Number of Biopsy Cores in Systematic Biopsy by Quintana, Liza, Ward, Ashley, Gerrin, Sean J, Genega, Elizabeth M, Rosen, Seymour, Sanda, Martin G, Wagner, Andrew A, Chang, Peter, DeWolf, William C, Ye, Huihui

“…Objective To compare the utility of saturation core biopsy and 12-core biopsy in detecting true Gleason grades, using final pathology in prostatectomy…”
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ErbB2 Signaling Increases Androgen Receptor Expression in Abiraterone-Resistant Prostate Cancer by Gao, Shuai, Ye, Huihui, Gerrin, Sean, Wang, Hongyun, Sharma, Ankur, Chen, Sen, Patnaik, Akash, Sowalsky, Adam G, Voznesensky, Olga, Han, Wanting, Yu, Ziyang, Mostaghel, Elahe A, Nelson, Peter S, Taplin, Mary-Ellen, Balk, Steven P, Cai, Changmeng

“…ErbB2 signaling appears to be increased and may enhance androgen receptor (AR) activity in a subset of patients with castration-resistant prostate cancer…”
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Positive feedback loop mediated by protein phosphatase 1α mobilization of P-TEFb and basal CDK1 drives androgen receptor in prostate cancer by Liu, Xiaming, Gao, Yanfei, Ye, HuiHui, Gerrin, Sean, Ma, Fen, Wu, Yiming, Zhang, Tengfei, Russo, Joshua, Cai, Changmeng, Yuan, Xin, Liu, Jihong, Chen, Shaoyong, Balk, Steven P

“…P-TEFb (CDK9/cyclin T) plays a central role in androgen receptor (AR)-mediated transactivation by phosphorylating both RNA polymerase 2 complex proteins and AR…”
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High-Throughput, Low Volume gDNA Extraction from Whole Blood Enabled by Covaris Adaptive Focused Acoustics (AFA) and oneTUBE-10 by Jansen, Lauren, Process, Vanessa, Amirault, Kristopher, Gerrin, Sean, Thomann, Ulrich

“…Extraction of genomic DNA (gDNA) from fresh whole blood is the first step in multiple translational research and molecular diagnostics applications, such as…”
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Mutation Profiling Indicates High Grade Prostatic Intraepithelial Neoplasia as Distant Precursors of Adjacent Invasive Prostatic Adenocarcinoma: Mutation Profile of HGPIN by Gerrin, Sean J., Sowalsky, Adam G., Balk, Steven P., Ye, Huihui

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Single molecule DNA intercalation in continuous homogenous elongational flow by Griffis, Joshua W, Safranovitch, Mikhail M, Vyas, Shilpi P, Gerrin, Sean, Protozanova, Ekaterina, Malkin, Gene, Meltzer, Robert H

“…Sequence-nonspecific staining of DNA with intercalating fluorophores is required for fluorescence-based length estimation of elongated DNA in optical mapping…”
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