Search Results - "Gernert, K M"
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Three-Dimensional Structure of Human Serum Albumin
Published in Science (American Association for the Advancement of Science) (09-06-1989)“…The three-dimensional structure of human serum albumin has been solved at 6.0 angstrom (Å) resolution by the method of multiple isomorphous replacement…”
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The Alacoil: A very tight, antiparallel coiled‐coil of helices
Published in Protein science (01-11-1995)“…The Alacoil is an antiparallel (rather than the usual parallel) coiled‐coil of α‐helices with Ala or another small residue in every seventh position, allowing…”
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The tyrosine corner: A feature of most greek key β‐barrel proteins
Published in Protein science (01-11-1994)“…The Tyr corner is a conformation in which a tyrosine (residue “Y”) near the beginning or end of an antiparallel β‐strand makes an H bond from its side‐chain OH…”
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Looking at proteins: representations, folding, packing, and design. Biophysical Society National Lecture, 1992
Published in Biophysical journal (01-11-1992)“…Looking at proteins is an active process of interpretation and selection, emphasizing some features and deleting others. Multiple representations are needed,…”
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Conserved amino acid motifs from the novel Piv/MooV family of transposases and site‐specific recombinases are required for catalysis of DNA inversion by Piv
Published in Molecular microbiology (01-02-2001)“…Piv, a site‐specific invertase from Moraxella lacunata, exhibits amino acid homology with the transposases of the IS110/IS492 family of insertion elements. The…”
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Multiple domains of the SIV Env protein determine virus replication efficiency and neutralization sensitivity
Published in Virology (New York, N.Y.) (05-02-2005)“…SIVmac239 and SIVmac1A11 are wild-type viruses encoding Env proteins with full-length or truncated cytoplasmic tails (CTs), respectively. A mutant designated…”
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Structural Features of Paramyxovirus F Protein Required for Fusion Initiation
Published in Biochemistry (Easton) (10-06-2003)“…On the basis of the coordinates of the related Newcastle disease virus (NDV) F protein, Valine-94, a determinant of measles virus (MV) cytopathicity, is…”
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The C-terminal Tail of UNC-60B (Actin Depolymerizing Factor/Cofilin) Is Critical for Maintaining Its Stable Association with F-actin and Is Implicated in the Second Actin-binding Site
Published in The Journal of biological chemistry (23-02-2001)“…Actin depolymerizing factor (ADF)/cofilin changes the twist of actin filaments by binding two longitudinally associated actin subunits. In the absence of an…”
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Initiation of human astrocytoma by clonal evolution of cells with progressive loss of p53 functions in a patient with a 283H TP53 germ-line mutation: Evidence for a precursor lesion
Published in Cancer research (Chicago, Ill.) (15-05-2002)“…Little is known about the genetic and molecular events leading to the early stages of human astrocytoma formation. To examine this issue, we analyzed the…”
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A simple apparatus for controlling nucleation and size in protein crystal growth
Published in Analytical biochemistry (01-01-1988)“…A simple device is described for controlling vapor equilibrium in macromolecular crystallization as applied to the protein crystal growth technique commonly…”
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Novel structural determinants on SIRPα that mediate binding to CD47
Published in The Journal of immunology (1950) (01-01-2008)Get full text
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Three New Isoforms of Caenorhabditis elegans UNC-89 Containing MLCK-like Protein Kinase Domains
Published in Journal of molecular biology (03-09-2004)“…In Caenorhabditis elegans, the gene unc- 89 is required for A-band organization of striated muscle. In mammals, a likely homolog of UNC-89, called obscurin,…”
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Saccharomyces cerevisiae Npc2p Is a Functionally Conserved Homologue of the Human Niemann-Pick Disease Type C 2 Protein, hNPC2
Published in Eukaryotic Cell (01-11-2005)“…Classifications Services EC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Titins in C. elegans with Unusual Features: Coiled-coil Domains, Novel Regulation of Kinase Activity and Two New Possible Elastic Regions
Published in Journal of molecular biology (2002)“…We report that there are previously unrecognized proteins in Caenorhabditis elegans that are similar to the giant muscle proteins called titins, and these are…”
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Puzzle pieces defined: locating common packing units in tertiary protein contacts
Published in Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing (1996)“…Puzzle pieces are defined as small packing units which make up the unique tertiary interactions in proteins. Anti-parallel and perpendicular helix-helix…”
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Looking at proteins: Representations, folding, packing, and design
Published in Biophysical journal (01-01-1992)“…Looking at proteins is an active process of interpretation and selection, emphasizing some features and deleting others. We are working on systems that test…”
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17
Comparing and Clustering Flow Cytometry Data
Published in 2008 IEEE International Conference on Bioinformatics and Biomedicine (01-01-2008)“…Flow cytometry technique produces large, multi-dimensional datasets of properties of individual cells that are helpful for biomedical science and clinical…”
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