Predictors of human papilloma virus (HPV) infection in Italian women

Predictors of human papilloma virus (HPV) infection in Italian women

HPV infection is a "necessary cause" of cervical cancer and it is sexually transmitted. Due to upcoming mass vaccination investigation on risk factors for infection is the basis to implement prophylactic strategy even in older women. The aim of the study was to evaluate predictors of high-...

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Bibliographic Details
Published in:Journal of medical virology Vol. 82; no. 11; pp. 1921 - 1927
Main Authors: Cercato, M.C, Mariani, L, Vocaturo, A, Carrone, A, Terrenato, I, Morano, G, Benevolo, M, Rollo, F, Germelli, C, Paolini, F, Venuti, A
Format: Journal Article
Language:English
Published: Hoboken Wiley Subscription Services, Inc., A Wiley Company 01-11-2010
Wiley
Wiley-Blackwell
Subjects:
Adolescent
Adult
Biological and medical sciences
cervical cancer
Epidemiology
Female
Fundamental and applied biological sciences. Psychology
Genotype
HPV
Human viral diseases
Humans
Infectious diseases
Italy - epidemiology
Mass Screening
Medical sciences
Microbiology
Miscellaneous
Multivariate Analysis
Papillomaviridae - classification
Papillomaviridae - genetics
Papillomaviridae - isolation & purification
Papillomavirus Infections - diagnosis
Papillomavirus Infections - epidemiology
Papillomavirus Infections - virology
Predictive Value of Tests
Prevalence
questionnaire
Risk Factors
Sexual Behavior
Surveys and Questionnaires
Viral diseases
Virology
Women's Health
Young Adult
Italy
Human
questionnaire
risk factors
Malignant tumor
Epidemiology
Female genital diseases
HPV
Infection
sexual behavior
Viral disease
Risk factor
Female
Papilloma
Benign neoplasm
Uterine cervix diseases
Cervical cancer
Cancer
Medicine
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Description
Summary:HPV infection is a "necessary cause" of cervical cancer and it is sexually transmitted. Due to upcoming mass vaccination investigation on risk factors for infection is the basis to implement prophylactic strategy even in older women. The aim of the study was to evaluate predictors of high-risk (HR) HPV infection in adult women. Between 2006 and 2008, 100 women aged >18 years, with no previous treatment for cervical lesions, were screened for HR HPV infection in Rome, Italy. Risk factors for HPV infection were investigated through a questionnaire including: ethnicity, religion, education, marital status, sexual behavior, gynecological and obstetrical history, smoking and alcohol intake. Multivariate analysis identified the "never married-separated/divorced" status (OR: 3.38; 95% CI: 1.14-10.12) as predictor of HPV infection, while having a higher age at the first sexual intercourse (FSI) shows a protective effect (OR: 0.84; 95% CI: 0.71-1.00). A trend for the association between the infection and having more than three lifetime partners was also observed (OR: 2.57; 95% CI: 0.86-7.71). No significant association was found for other demographic characteristics investigated. These findings provide a contribution in the knowledge of an adult population defining a "high-risk" sexual behavioral profile and could be helpful to target prophylactic strategies in older woman. J. Med. Virol. 82:1921-1927, 2010.
Bibliography:http://dx.doi.org/10.1002/jmv.21887
ark:/67375/WNG-DM8Q7BZC-8
The authors have no conflict of interest to disclose.
The Italian Ministry of Health (partial support)
istex:716333853C4398A1817E93D34458F11721FCABF7
ArticleID:JMV21887
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0146-6615
1096-9071
DOI:10.1002/jmv.21887