Search Results - "Germann, U.A"

Expression of the human multidrug resistance cDNA in insect cells generates a high activity drug-stimulated membrane ATPase by SARKADI, B, PRICE, E. M, BOUCHER, R. C, GERMANN, U. A, SCARBOROUGH, G. A

“…Drug-resistant tumor cells actively extrude a variety of chemotherapeutic agents by the action of the multi-drug resistance (MDR1) gene product, the plasma…”
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P-glycoprotein—A mediator of multidrug resistance in tumour cells by Germann, U.A.

“…Simultaneous resistance of tumour cells to multiple cytotoxic drugs (multidrug resistance, MDR) is a major limitation to the successful chemotherapeutic…”
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Isolation and structural organization of the Neurospora crassa copper metallothionein gene by Münger, K., Germann, U.A., Lerch, K.

“…The Neurospora crassa copper metallothionein gene was cloned and its complete nucleotide sequence is reported. Enriched metallothionein mRNA was used as a…”
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Fluorescent cellular indicators are extruded by the multidrug resistance protein by HOMOLYA, L, HOLLO, Z, GERMANN, U. A, PASTAN, I, GOTTESMAN, M. M, SARKADI, B

“…In this report we show that NIH-3T3 mouse fibroblasts stably expressing the human multidrug transporter (MDR1 or P-glycoprotein), in contrast to the control…”
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Genetic Analysis of the Multidrug Transporter by Gottesman, M M, Hrycyna, C A, Schoenlein, P V, Germann, U A, Pastan, I

“…The analysis of how human cancers evade chemotherapy has revealed a rich variety of cell-based genetic changes resulting in drug resistance. One of the best…”
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Expression of the human multidrug transporter in insect cells by a recombinant baculovirus by Germann, Ursula A, Willingham, Mark C, Pastan, Ira, Gottesman, Michael M

“…The plasma membrane associated human multidrug resistance (MDR1) gene product, known as the 170-kDa P-glycoprotein or the multidrug transporter, acts as an…”
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Characterization of two allelic forms of Neurospora crassa laccase. Amino- and carboxyl-terminal processing of a precursor by Germann, U A, Müller, G, Hunziker, P E, Lerch, K

“…The complete structures of the laccase genes isolated from two different Neurospora crassa wild-type strains are described. The genes were cloned by screening…”
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Regulation of laccase synthesis in induced Neurospora crassa cultures by Linden, R.M. (Zuerich Univ. (Switzerland). Biochemisches Inst.), Schilling, B.C, Germann, U.A, Lerch, K

“…Rapidly growing cultures of N. crassa do not produce laccase. Exposure of this fungus to different inducing agents leads to a de novo biosynthesis of…”
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