Search Results - "German, Rana"
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Exploring breast tissue microbial composition and the association with breast cancer risk factors
Published in Breast cancer research : BCR (10-07-2023)“…Microbial dysbiosis has emerged as an important element in the development and progression of various cancers, including breast cancer. However, the microbial…”
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2
Global identification of microRNA-target RNA pairs by parallel analysis of RNA ends
Published in Nature biotechnology (01-08-2008)“…MicroRNAs (miRNAs) are important regulatory molecules in most eukaryotes and identification of their target mRNAs is essential for their functional analysis…”
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3
Genome-wide analysis for discovery of rice microRNAs reveals natural antisense microRNAs (nat-miRNAs)
Published in Proceedings of the National Academy of Sciences - PNAS (25-03-2008)“…Small RNAs (21-24 nt) are involved in gene regulation through translation inhibition, mRNA cleavage, or directing chromatin modifications. In rice, currently…”
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Composition and Functional Potential of the Human Mammary Microbiota Prior to and Following Breast Tumor Diagnosis
Published in mSystems (28-06-2022)“…Microbiota studies have reported changes in the microbial composition of the breast upon cancer development. However, results are inconsistent and limited to…”
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Aberrant epigenetic and transcriptional events associated with breast cancer risk
Published in Clinical epigenetics (09-02-2022)“…Genome-wide association studies have identified several breast cancer susceptibility loci. However, biomarkers for risk assessment are still missing. Here, we…”
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Author Correction: Upregulation of lipid metabolism genes in the breast prior to cancer diagnosis
Published in NPJ breast cancer (17-06-2024)Get full text
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FAM83A is a potential biomarker for breast cancer initiation
Published in Biomarker research (19-02-2022)“…Family with sequence similarity 83 member A (FAM83A) presents oncogenic properties in several cancers including breast cancer. Recently, we reported FAM83A…”
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Abstract B067: Markers of vitamin D3 activity in normal breast tissue and subsequent breast cancer: A pilot study
Published in Cancer epidemiology, biomarkers & prevention (01-12-2023)“…Abstract Vitamin D3 (1,25-dihydroxyvitamin D3 (1,25(OH)2D3)), has been hypothesized to be associated with breast cancer initiation and progression through…”
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Abstract 4641: Metabolic reprogramming of the breast contributes to a cancer promoting milieu
Published in Cancer research (Chicago, Ill.) (01-07-2019)“…Abstract In addition to the accumulation of pro-oncogenic mutations in the epithelial cells, the tumorigenic process involves the dysregulation of the…”
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10
Single-nucleus chromatin accessibility and transcriptomic map of breast tissues of women of diverse genetic ancestry
Published in Nature medicine (09-08-2024)“…Single-nucleus analysis allows robust cell-type classification and helps to establish relationships between chromatin accessibility and cell-type-specific gene…”
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Abstract P1-13-03: Prospective, placebo-controlled, randomized study of metformin for breast cancer prevention in overweight/ obese women
Published in Cancer research (Chicago, Ill.) (15-02-2020)“…Abstract Background: In several epidemiologic studies, the oral anti-diabetic medication metformin is associated with lower cancer incidence and diminished…”
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Biofilm-derived oxylipin 10-HOME mediated immune response in women with breast implants
Published in The Journal of clinical investigation (01-02-2024)“…Breast implant illness (BII) is a poorly understood disease in which patients develop symptoms typical of autoimmune conditions following breast implantation…”
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13
Systemic and tissue microRNAs changes in early phase of breast cancer development
Published in Journal of clinical oncology (20-05-2018)“…Abstract only…”
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14
Epigenetic control of breast cancer susceptibility
Published in Journal of clinical oncology (20-05-2020)“…Abstract only 1560 Background: Epigenetic mechanisms such as DNA methylation are important regulators of gene expression and are frequently dysregulated early…”
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15
Upregulation of lipid metabolism genes in the breast prior to cancer diagnosis
Published in NPJ breast cancer (06-10-2020)“…Histologically normal tissue adjacent to the tumor can provide insight of the microenvironmental alterations surrounding the cancerous lesion and affecting the…”
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Abstract P5-08-16: Molecular landscape of the breasts of women at high risk for breast cancer
Published in Cancer research (Chicago, Ill.) (15-02-2020)“…Abstract Background: Despite advances in breast cancer diagnosis and treatment, there is a critical need to identify the determinants of breast cancer…”
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17
Biofilm-derived oxylipin 10-HOME-mediated immune response in women with breast implants
Published in The Journal of clinical investigation (01-02-2024)“…This study investigates a mechanistic link of bacterial biofilm-mediated host-pathogen interaction leading to immunological complications associated with…”
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Abstract 5054: Transcriptional changes in breast cancer initiation
Published in Cancer research (Chicago, Ill.) (01-07-2018)“…Abstract Background: Identifying the earliest stages of breast cancer carcinogenesis, present well before any clinical signs of disease, is the necessary…”
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Abstract 1962: Oncologic anthropology-impact of Duffy adaptive trait on breast epithelial and tumor cell biology
Published in Cancer research (Chicago, Ill.) (04-04-2023)“…Abstract Adaptation to diverse environments during human evolution including those conditions that favor certain infectious diseases to become endemic in a…”
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