Search Results - "Germain, Stéphane"

Extracellular matrix scaffolding in angiogenesis and capillary homeostasis by Marchand, Marion, Monnot, Catherine, Muller, Laurent, Germain, Stéphane

“…The extracellular matrix (ECM) of blood vessels, which is composed of both the vascular basement membrane (BM) and the interstitial ECM is identified as a…”
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Microbiota depletion promotes browning of white adipose tissue and reduces obesity by Suárez-Zamorano, Nicolas, Fabbiano, Salvatore, Chevalier, Claire, Stojanović, Ozren, Colin, Didier J, Stevanović, Ana, Veyrat-Durebex, Christelle, Tarallo, Valentina, Rigo, Dorothée, Germain, Stéphane, Ilievska, Miroslava, Montet, Xavier, Seimbille, Yann, Hapfelmeier, Siegfried, Trajkovski, Mirko

“…Browning of white adipose tissue is induced by depletion of the microbiota, improving metabolic disease and reducing obesity. Brown adipose tissue (BAT)…”
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Blood endothelium transition and phenotypic plasticity: A key regulator of integrity/permeability in response to ischemia by Bréchot, Nicolas, Rutault, Alexandre, Marangon, Iris, Germain, Stéphane

“…In the human body, the 10 blood endothelial cells (ECs) which cover a surface of 500-700 m (Mai et al., 2013) are key players of tissue homeostasis, remodeling…”
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The no-reflow phenomenon: State of the art by Bouleti, Claire, Mewton, Nathan, Germain, Stéphane

“…Summary Primary percutaneous coronary intervention (PCI) is the best available reperfusion strategy for acute ST-segment elevation myocardial infarction…”
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Coupling between Myogenesis and Angiogenesis during Skeletal Muscle Regeneration Is Stimulated by Restorative Macrophages by Latroche, Claire, Weiss-Gayet, Michèle, Muller, Laurent, Gitiaux, Cyril, Leblanc, Pascal, Liot, Sophie, Ben-Larbi, Sabrina, Abou-Khalil, Rana, Verger, Nicolas, Bardot, Paul, Magnan, Mélanie, Chrétien, Fabrice, Mounier, Rémi, Germain, Stéphane, Chazaud, Bénédicte

“…In skeletal muscle, new functions for vessels have recently emerged beyond oxygen and nutrient supply, through the interactions that vascular cells establish…”
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Lysyl oxidase-like protein-2 regulates sprouting angiogenesis and type IV collagen assembly in the endothelial basement membrane by Bignon, Marine, Pichol-Thievend, Cathy, Hardouin, Julie, Malbouyres, Marilyne, Bréchot, Nicolas, Nasciutti, Luiz, Barret, Alain, Teillon, Jérémie, Guillon, Emilie, Etienne, Eric, Caron, Michel, Joubert-Caron, Raymonde, Monnot, Catherine, Ruggiero, Florence, Muller, Laurent, Germain, Stéphane

“…Sprouting angiogenesis is associated with extensive extracellular matrix (ECM) remodeling. The molecular mechanisms involved in building the vascular…”
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In vitro 3D Systems to Model Tumor Angiogenesis and Interactions With Stromal Cells by Brassard-Jollive, Noémie, Monnot, Catherine, Muller, Laurent, Germain, Stéphane

“…In vitro 3D culture systems provide promising tools for screening novel therapies and understanding drug resistance mechanisms in cancer because they are…”
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Hypoxia-driven angiogenesis: role of tip cells and extracellular matrix scaffolding by Germain, Stéphane, Monnot, Catherine, Muller, Laurent, Eichmann, Anne

“…PURPOSE OF REVIEWAngiogenesis is a highly coordinated tissue remodeling process leading to blood vessel formation. Hypoxia triggers angiogenesis via induction…”
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Dynamics of Endothelial Engagement and Filopodia Formation in Complex 3D Microscaffolds by Ucla, Pierre, Ju, Xingming, Demircioglu, Melisa, Baiz, Sarah, Muller, Laurent, Germain, Stéphane, Monnot, Catherine, Semetey, Vincent, Coscoy, Sylvie

“…The understanding of endothelium-extracellular matrix interactions during the initiation of new blood vessels is of great medical importance; however, the…”
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ANGPTL4, a multifaceted protein at the cross-talk between metabolism and cardiovascular disorders by Bouleti, Claire, Monnot, Catherine, Germain, Stéphane

“…We read with interest the letter from Fei Luo et al. Indeed, whether developing therapeutic agents aimed at long-term blocking ANGPTL4 is a matter of intense…”
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Angiogenesis and full thickness wound repair in a cell sheet-based vascularized skin substitute by Mauroux, Adèle, Gofflo, Sandrine, Breugnot, Josselin, Malbouyres, Marilyne, Atlas, Yoann, Ardidie-Robouant, Corinne, Marchand, Laëtitia, Monnot, Catherine, Germain, Stéphane, Bordes, Sylvie, Closs, Brigitte, Ruggiero, Florence, Muller, Laurent

“…Skin tissue engineering is undergoing tremendous expansion as a result from clinical needs, mandatory replacement of animal models and development of new…”
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Anti-Markovnikov Hydroamination of Aromatic Alkenes with Secondary Amines Catalyzed by Easily Accessible Yttrium Complexes by Germain, Stéphane, Schulz, Emmanuelle, Hannedouche, Jérôme

“…Binaphthylamido alkyl yttrium complexes have been proven to promote the anti‐Markovnikov addition between various styrene derivatives and secondary amines…”
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Autocrine and Paracrine Angiopoietin 1/Tie-2 Signaling Promotes Muscle Satellite Cell Self-Renewal by Abou-Khalil, Rana, Le Grand, Fabien, Pallafacchina, Giorgia, Valable, Samuel, Authier, François-Jérôme, Rudnicki, Michael A., Gherardi, Romain K., Germain, Stéphane, Chretien, Fabrice, Sotiropoulos, Athanassia, Lafuste, Peggy, Montarras, Didier, Chazaud, Bénédicte

“…Mechanisms governing muscle satellite cell withdrawal from cell cycle to enter into quiescence remain poorly understood. We studied the role of angiopoietin 1…”
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Microvascular maturation by mesenchymal stem cells in vitro improves blood perfusion in implanted tissue constructs by Atlas, Yoann, Gorin, Caroline, Novais, Anita, Marchand, Marion F., Chatzopoulou, Eirini, Lesieur, Julie, Bascetin, Rumeyza, Binet-Moussy, Clément, Sadoine, Jeremy, Lesage, Matthieu, Opsal-Vital, Sibylle, Péault, Bruno, Monnot, Catherine, Poliard, Anne, Girard, Philippe, Germain, Stéphane, Chaussain, Catherine, Muller, Laurent

“…Blood perfusion of grafted tissue constructs is a hindrance to the success of stem cell-based therapies by limiting cell survival and tissue regeneration…”
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Glucagon-like Peptide 1 Receptor Agonists, Diabetic Retinopathy and Angiogenesis: The AngioSafe Type 2 Diabetes Study by Gaborit, Bénédicte, Julla, Jean-Baptiste, Besbes, Samaher, Proust, Matthieu, Vincentelli, Clara, Alos, Benjamin, Ancel, Patricia, Alzaid, Fawaz, Garcia, Rodrigue, Mailly, Philippe, Sabatier, Florence, Righini, Maud, Gascon, Pierre, Matonti, Frédéric, Houssays, Marie, Goumidi, Louisa, Vignaud, Lucile, Guillonneau, Xavier, Erginay, Ali, Dupas, Bénédicte, Marie-Louise, Jennifer, Autié, Marianne, Vidal-Trecan, Tiphaine, Riveline, Jean-Pierre, Venteclef, Nicolas, Massin, Pascale, Muller, Laurent, Dutour, Anne, Gautier, Jean-François, Germain, Stéphane

“…Abstract Aims Recent trials provide conflicting results on the association between glucagon-like peptide 1 receptor agonists (GLP-1RA) and diabetic retinopathy…”
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VEGF-A plasma levels are associated with microvascular obstruction in patients with ST-segment elevation myocardial infarction by Garcia, Rodrigue, Bouleti, Claire, Sirol, Marc, Logeart, Damien, Monnot, Catherine, Ardidie-Robouant, Corinne, Caligiuri, Giuseppina, Mercadier, Jean-Jacques, Germain, Stéphane

“…Microvascular obstruction (MVO) is associated with poor outcome after ST-segment elevation myocardial infarction (STEMI). Vascular endothelial growth factor-A…”
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FX06 to rescue SARS-CoV-2-induced acute respiratory distress syndrome: a randomized clinical trial by Guérin, Emmanuelle, Belin, Lisa, Franchineau, Guillaume, Le Guennec, Loïc, Hajage, David, Diallo, Mamadou Hassimiou, Frapard, Thomas, Le Fèvre, Lucie, Luyt, Charles-Edouard, Combes, Alain, Germain, Stéphane, Hayon, Jan, Asfar, Pierre, Bréchot, Nicolas

“…Abstract Background Vascular leakage is a major feature of acute respiratory distress syndrome (ARDS). We aimed to evaluate the efficacy of FX06, a drug under…”
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Lysyl oxidase‐like 2 (LOXL2)‐mediated cross‐linking of tropoelastin by Schmelzer, Christian E. H., Heinz, Andrea, Troilo, Helen, Lockhart‐Cairns, Michael P., Jowitt, Thomas A., Marchand, Marion F., Bidault, Laurent, Bignon, Marine, Hedtke, Tobias, Barret, Alain, McConnell, James C., Sherratt, Michael J., Germain, Stéphane, Hulmes, David J. S., Baldock, Clair, Muller, Laurent

“…ABSTRACTLysyl oxidases (LOXs) play a central role in extracellular matrix remodeling during development and tumor growth and fibrosis through cross‐linking of…”
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Extracellular Matrix–Bound Angiopoietin-Like 4 Inhibits Endothelial Cell Adhesion, Migration, and Sprouting and Alters Actin Cytoskeleton by Cazes, Aurélie, Galaup, Ariane, Chomel, Clémence, Bignon, Marine, Bréchot, Nicolas, Jan, Sébastien Le, Weber, Holger, Corvol, Pierre, Muller, Laurent, Germain, Stéphane, Monnot, Catherine

“…Angiopoietin-like 4 (ANGPTL4) is a secreted protein that belongs to the angiopoietin family and is involved in angiogenesis and metabolism regulation. We…”
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Enhanced angiogenesis and increased cardiac perfusion after myocardial infarction in protein tyrosine phosphatase 1B‐deficient mice by Besnier, Marie, Galaup, Ariane, Nicol, Lionel, Henry, Jean‐Paul, Coquerel, David, Gueret, Alexandre, Mulder, Paul, Brakenhielm, Ebba, Thuillez, Christian, Germain, Stéphane, Richard, Vincent, Ouvrard‐Pascaud, Antoine

“…The protein tyrosine phosphatase 1B (PTP1B) modulates tyrosine kinase receptors, among which is the vascular endothelial growth factor receptor type 2…”
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