Search Results - "Germain, Bryan St"

A novel patch assembly domain in Num1 mediates dynein anchoring at the cortex during spindle positioning by Tang, Xianying, Germain, Bryan St, Lee, Wei-Lih

“…During mitosis in budding yeast, cortically anchored dynein generates pulling forces on astral microtubules to position the mitotic spindle across the…”
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Quantitative analysis of Pac1/LIS1-mediated dynein targeting: Implications for regulation of dynein activity in budding yeast by Markus, Steven M., Plevock, Karen M., St. Germain, Bryan J., Punch, Jesse J., Meaden, Christopher W., Lee, Wei-Lih

“…LIS1 is a critical regulator of dynein function during mitosis and organelle transport. Here, we investigated how Pac1, the budding yeast LIS1 homologue,…”
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Integration of cell line and process development to overcome the challenge of a difficult to express protein by Alves, Christina S., Gilbert, Alan, Dalvi, Swati, Germain, Bryan St, Xie, Wenqi, Estes, Scott, Kshirsagar, Rashmi, Ryll, Thomas

“…This case study addresses the difficulty in achieving high level expression and production of a small, very positively charged recombinant protein. The novel…”
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