Search Results - "Germà Lluch, José Ramón"

Conventional-Dose Versus High-Dose Chemotherapy As First Salvage Treatment in Male Patients With Metastatic Germ Cell Tumors: Evidence From a Large International Database by LORCH, Anja, BASCOUL-MOLLEVI, Caroline, RAMON GERMA-LLUCH, Jose, POWLES, Thomas, KOLLMANNSBERGER, Christian, BEYER, Jörg, KRAMAR, Andrew, EINHORN, Lawrence, NECCHI, Andrea, MASSARD, Christophe, DE GIORGI, Ugo, FLECHON, Aude, MARGOLIN, Kim, LOTZ, Jean-Pierre

“…Conventional-dose chemotherapy (CDCT) and high-dose chemotherapy (HDCT) may both be successfully used as salvage treatment for patients with metastatic germ…”
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Low frequency of recurrent BRCA1 and BRCA2 mutations in Spain by Llort, Gemma, Muñoz, Carmen Yagüe, Tuser, Mercè Peris, Guillermo, Ignacio Blanco, Lluch, José Ramón Germà, Bale, Allen E., Franco, Mayra Alvarez

“…BRCA1 and BRCA2 mutations underlie a substantial proportion of all hereditary breast cancer. The mutational spectrum in these genes is very broad, with…”
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Pay-for-performance schemes: 10 years' experience in a comprehensive cancer center by Clopés Estela, Ana, Soler Rotllant, Francesc, Germà Lluch, José Ramón, Calle Rodríguez, Candela

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Pay-for-performance schemes: 10 years’ experience in a comprehensive cancer center by Clopés Estela, Ana, Soler Rotllant, Francesc, Germà Lluch, José Ramón, Calle Rodríguez, Candela

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The PDGFRβ-AKT Pathway Contributes to CDDP-Acquired Resistance in Testicular Germ Cell Tumors by JULIACHS, M, MUNOZ, C, VINALS, F, MOUTINHO, C. A, VIDAL, A, CONDOM, E, ESTELLER, M, GRAUPERA, M, CASANOVAS, O, GERMA, J. R, VILLANUEVA, A

“…We examined whether PI3K-AKT or extracellular signal-regulated kinase (ERK) signaling pathways could play a role in the development of cisplatin (CDDP)…”
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The impact of KRAS mutations on VEGF-A production and tumour vascular network by Figueras, Agnès, Arbos, Maria Antonia, Quiles, Maria Teresa, Viñals, Francesc, Germà, Josep Ramón, Capellà, Gabriel

“…The malignant potential of tumour cells may be influenced by the molecular nature of KRAS mutations being codon 13 mutations less aggressive than codon 12…”
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Oncologic functional units by Germa Lluch, José Ramón

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Sunitinib Inhibits Tumor Growth and Synergizes with Cisplatin in Orthotopic Models of Cisplatin-Sensitive and Cisplatin-Resistant Human Testicular Germ Cell Tumors by CASTILLO-AVILA, Wilmar, PIULATS, Josep Maria, VINALS, Francesc, GARCIA DEL MURO, Xavier, VIDAL, August, CONDOM, Enric, CASANOVAS, Oriol, MORA, Josefina, RAMON GERMA, Josep, CAPELLA, Gabriel, VILLANUEVA, Alberto

“…Purpose: Germ cell tumors (GCT) of the testis are highly curable, but those patients who are refractory to cisplatin (CDDP)-based combination chemotherapy have…”
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The PDGFRβ-AKT pathway contributes to CDDP-acquired resistance in testicular germ cell tumors by Juliachs Milà, Mercè, Muñoz, C, Moutinho, Cátia, Vidal-Bel, August, Condom i Mundó, Enric, Esteller, Manel, Graupera i Garcia-Milà, Mariona, Casanovas i Casanovas, Oriol, Germà Lluch, José Ramón, Villanueva Garatachea, Alberto, Viñals Canals, Francesc

“…Purpose: we examined whether PI3K-AKT or extracellular signal-regulated kinase (ERK) signaling pathways could play a role in the development of cisplatin…”
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The PDGFRβ-AKT pathway contributes to CDDP-acquired resistance in testicular germ cell tumors by Juliachs Milà, Mercè, Muñoz, C, Moutinho, Cátia, Vidal-Bel, August, Condom i Mundó, Enric, Esteller, Manel, Graupera i Garcia-Milà, Mariona, Casanovas i Casanovas, Oriol, Germà Lluch, José Ramón, Villanueva Garatachea, Alberto, Viñals Canals, Francesc

“…Purpose: we examined whether PI3K-AKT or extracellular signal-regulated kinase (ERK) signaling pathways could play a role in the development of cisplatin…”
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Effectivity of pazopanib treatment in orthotopic models of human testicular germ cell tumors by Juliachs, Mercè, Vidal, August, Del Muro, Xavier Garcia, Piulats, Josep M, Condom, Enric, Casanovas, Oriol, Graupera, Mariona, Germà, Jose R, Villanueva, Alberto, Viñals, Francesc

“…Cisplatin (CDDP) resistance in testicular germ cell tumors (GCTs) is still a clinical challenge, and one associated with poor prognosis. The purpose of this…”
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Prognostic Factors in Patients With Metastatic Germ Cell Tumors Who Experienced Treatment Failure With Cisplatin-Based First-Line Chemotherapy by Lorch, Anja, Beyer, Jörg, Bascoul-Mollevi, Caroline, Kramar, Andrew, Einhorn, Lawrence H, Necchi, Andrea, Massard, Christophe, De Giorgi, Ugo, Fléchon, Aude, Margolin, Kim A, Lotz, Jean-Pierre, Germa Lluch, Jose Ramon, Powles, Thomas, Kollmannsberger, Christian K

“…To develop a prognostic model in patients with germ cell tumors (GCT) who experience treatment failure with cisplatin-based first-line chemotherapy. Data from…”
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Antiangiogenic effect of gemcitabine following metronomic administration in a pancreas cancer model by Laquente, Berta, Lacasa Salavert, Cristina, Ginestà, Mireia M, Casanovas i Casanovas, Oriol, Figueras i Amat, Agnès, Galán, Maica, García Ribas, Ignacio, Germà Lluch, José Ramón, Capellá, G. (Gabriel), Viñals Canals, Francesc

“…Gemcitabine shows a marked antitumor effect as a result of its cytotoxic action toward proliferative cells. In this article, we aim to investigate the…”
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The impact of KRAS mutations on VEGF-A production and tumour vascular network by Figueras i Amat, Agnès, Arbós i Via, Maria Antònia, Quiles, Maria Teresa, Viñals Canals, Francesc, Germà Lluch, José Ramón, Capellá, G. (Gabriel)

“…Background: The malignant potential of tumour cells may be influenced by the molecular nature of KRAS mutations being codon 13 mutations less aggressive than…”
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ErbBs inhibition by lapatinib blocks tumor growth in an orthotopic model of human testicular germ cell tumor by Juliachs, M., Castillo‐Ávila, W., Vidal, A., Piulats, J.M., Garcia del Muro, X., Condom, E., Hernández‐Losa, J., Teixidó, C., Pandiella, A., Graupera, M., Casanovas, O., Germà, J.R., Villanueva, A., Viñals, F.

“…In this work, we have analyzed the expression of different members of the ErbB family in human samples of testicular germ cell tumors (GCTs). We observed…”
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Treatment of cancer with oral drugs: a position statement by the Spanish Society of Medical Oncology (SEOM) by Colomer, R., Alba, E., González-Martin, A., Paz-Ares, L., Martín, M., Llombart, A., Rodríguez Lescure, Á., Salvador, J., Albanell, J., Isla, D., Lomas, M., Rodríguez, C.A., Trigo, J.M., Germà, J.R., Bellmunt, J., Tabernero, J., Rosell, R., Aranda, E., Cubedo, R., Baselga, J.

“…Cancer treatment involves the participation of multiple medical specialties and, as our knowledge of the disease increases, this fact becomes even more…”
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Lung resistance-related protein as a predictor of clinical outcome in advanced testicular germ-cell tumours by ZURITA, A. J, DIESTRA, J. E, CONDOM, E, GARCIA DEL MURO, X, SCHEFFER, G. L, SCHEPER, R. J, PEREZ, J, GERMA-LLUCH, J. R, IZQUIERDO, M. A

“…This study was undertaken to investigate the expression and predictive value for outcome of multidrug resistance-associated (MDR) proteins P-glycoprotein…”
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Phase II multicentre study of docetaxel plus cisplatin in patients with advanced urothelial cancer by GARCIA DEL MURO, X, MARCUELLO, E, GUMA, J, PAZ-ARES, L, CLIMENT, M. A, CARLES, J, SANCHEZ PARRA, M, TISAIRE, J. L, MAROTO, P. JR, GERMA, J. R

“…A multicentre phase II trial was undertaken to evaluate the activity and toxicity of docetaxel plus cisplatin as first-line chemotherapy in patients with…”
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Survival results in five malignant neoplasms separated by a decade at Institut Català d’Oncologia, Spain by Germá-Lluch, José Ramón, Petriz, Lourdes, Lopez, Pau, Asensio, Esther

“…Five years’ data relative survival (RS) is presented in 3 solid tumours: breast, colorectal (CRC) and lung and 2 haematologic neoplasms: large B cell lymphoma…”
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Low frequency of recurrent BRCA1 and BRCA2 mutations in Spain: Mutations in Brief by Llort, Gemma, Muñoz, Carmen Yagüe, Tuser, Mercè Peris, Guillermo, Ignacio Blanco, Lluch, José Ramón Germà, Bale, Allen E., Franco, Mayra Alvarez

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