Search Results - "Germà, Josep Ramón"
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1
Tumor Thymidylate Synthase 1494del6 Genotype As a Prognostic Factor in Colorectal Cancer Patients Receiving Fluorouracil-Based Adjuvant Treatment
Published in Journal of clinical oncology (01-04-2006)“…The purpose of this study was to analyze the value of germline and tumor thymidylate synthase (TS) genotyping as a prognostic marker in a series of colorectal…”
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2
Antiangiogenic effect of gemcitabine following metronomic administration in a pancreas cancer model
Published in Molecular cancer therapeutics (01-03-2008)“…Gemcitabine shows a marked antitumor effect as a result of its cytotoxic action toward proliferative cells. In this article, we aim to investigate the…”
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3
Efficacy and safety of concurrent trastuzumab plus weekly paclitaxel–FEC as primary therapy for HER2-positive breast cancer in everyday clinical practice
Published in Breast cancer research and treatment (01-08-2012)“…One of the most efficacious primary therapies in HER2-positive breast cancer was published by the M.D. Anderson group in 2005. This randomized trial evaluated…”
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4
Pre-clinical validation of early molecular markers of sensitivity to aromatase inhibitors in a mouse model of post-menopausal hormone-sensitive breast cancer
Published in Breast cancer research and treatment (01-06-2008)“…Introduction Changes in breast cancer cell biology following hormonal treatment have been claimed as promising predictor markers of clinical benefit even…”
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5
Sunitinib Inhibits Tumor Growth and Synergizes with Cisplatin in Orthotopic Models of Cisplatin-Sensitive and Cisplatin-Resistant Human Testicular Germ Cell Tumors
Published in Clinical cancer research (15-05-2009)“…Purpose: Germ cell tumors (GCT) of the testis are highly curable, but those patients who are refractory to cisplatin (CDDP)-based combination chemotherapy have…”
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6
Common genetic evolutionary pathways in familial adenomatous polyposis tumors
Published in Cancer research (Chicago, Ill.) (15-09-2003)“…Cancer cells progress through the accumulation of genetic alterations. Familial adenomatous polyposis (FAP) tumors provide an excellent model to unravel the…”
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7
Phase II multicentre study of temozolomide in combination with interferon alpha-2b in metastatic malignant melanoma
Published in Melanoma research (01-08-2006)“…Temozolomide is a novel oral alkylating agent, active against metastatic melanoma. Combinations of chemotherapy and biological response modifiers have been…”
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8
CA-125 response patterns in patients with recurrent ovarian cancer treated with pegylated liposomal doxorubicin (PLD)
Published in International journal of gynecological cancer (01-01-2010)“…: In recurrent ovarian cancer, CA-125 could be the only objective response criteria. This study analyzes response patterns regarding CA-125 in responders…”
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9
Molecular bases of platinum-resistance in testicular cancer
Published in Archivos españoles de urología (01-06-2013)“…Cisplatin has been the cornerstone of germ cell testicular tumors therapy since its introduction more tan 30 years ago, and a basic part of the schemes given…”
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10
The impact of KRAS mutations on VEGF-A production and tumour vascular network
Published in BMC cancer (18-03-2013)“…The malignant potential of tumour cells may be influenced by the molecular nature of KRAS mutations being codon 13 mutations less aggressive than codon 12…”
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11
A phase I clinical and pharmacokinetic study of paclitaxel and docetaxel given in combination in patients with solid tumours
Published in European journal of cancer (1990) (01-08-2006)“…The aim of this study was to determine the safety and feasibility profile of paclitaxel (PTX) and docetaxel (DTX) in combination and the pharmacokinetic and…”
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12
Impact on budget of new drugs for colorectal cancer treatment
Published in Medicina clínica (23-06-2007)“…To assess the impact on the medicines budget of the introduction of new treatments in colorectal cancer, as monoclonal antibodies cetuximab and bevacizumab and…”
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13
Does Induction Chemotherapy Still Have a Role in Larynx Preservation Strategies? The Experience of Institut Catala d'Oncologia in Stage III Larynx Carcinoma
Published in The Laryngoscope (01-09-2006)“…Background: Radiotherapy with concurrent cisplatin is the standard alternative to total laryngectomy for patients with locally advanced laryngeal cancer. The…”
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14
Founder mutation in familial adenomatous polyposis (FAP) in the Balearic Islands
Published in Cancer genetics and cytogenetics (01-04-2005)“…The incidence of familial adenomatous polyposis (FAP) is approximately 7.4 per 100,000 inhabitants. APC gene mutations have been found in 60–70% of all FAP…”
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15
Patterns of participation in clinical trials among cancer patients: a prospective study
Published in Medicina clínica (08-05-2010)Get more information
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16
Evaluation of clinical research studies in a comprehensive cancer center
Published in Medicina clínica (21-02-2004)“…The number of clinical trials in cancer patients has experienced an important growth during last years. However, it is difficult to find data showing this…”
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Importancia de la valoración geriátrica en las personas mayores con cáncer
Published in Revista española de geriatría y gerontología (2010)Get full text
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Importance of geriatric assessment in the elderly with cancer
Published in Revista española de geriatría y gerontología (01-05-2010)Get full text
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19
Lessons learned in the implementation of a cancer care network in Catalonia
Published in Journal of management & marketing in healthcare (01-04-2009)Get full text
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20
Giant parallel tube arrays (PTAs), a new type of lymphocyte inclusion
Published in Leukemia (01-12-1994)“…In a 56-year-old male patient, receiving chemotherapy after radical surgery for bladder carcinoma, an unusual type of cytoplasmic inclusion was discovered in…”
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