Search Results - "Gerik, Kimberly J."

Analysis of the genome and transcriptome of Cryptococcus neoformans var. grubii reveals complex RNA expression and microevolution leading to virulence attenuation by Janbon, Guilhem, Ormerod, Kate L, Paulet, Damien, Byrnes, 3rd, Edmond J, Yadav, Vikas, Chatterjee, Gautam, Mullapudi, Nandita, Hon, Chung-Chau, Billmyre, R Blake, Brunel, François, Bahn, Yong-Sun, Chen, Weidong, Chen, Yuan, Chow, Eve W L, Coppée, Jean-Yves, Floyd-Averette, Anna, Gaillardin, Claude, Gerik, Kimberly J, Goldberg, Jonathan, Gonzalez-Hilarion, Sara, Gujja, Sharvari, Hamlin, Joyce L, Hsueh, Yen-Ping, Ianiri, Giuseppe, Jones, Steven, Kodira, Chinnappa D, Kozubowski, Lukasz, Lam, Woei, Marra, Marco, Mesner, Larry D, Mieczkowski, Piotr A, Moyrand, Frédérique, Nielsen, Kirsten, Proux, Caroline, Rossignol, Tristan, Schein, Jacqueline E, Sun, Sheng, Wollschlaeger, Carolin, Wood, Ian A, Zeng, Qiandong, Neuvéglise, Cécile, Newlon, Carol S, Perfect, John R, Lodge, Jennifer K, Idnurm, Alexander, Stajich, Jason E, Kronstad, James W, Sanyal, Kaustuv, Heitman, Joseph, Fraser, James A, Cuomo, Christina A, Dietrich, Fred S

“…Cryptococcus neoformans is a pathogenic basidiomycetous yeast responsible for more than 600,000 deaths each year. It occurs as two serotypes (A and D)…”
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Role of Cryptococcus neoformans Rho1 GTPases in the PKC1 Signaling Pathway in Response to Thermal Stress by Lam, Woei C, Gerik, Kimberly J, Lodge, Jennifer K

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PKC1 Is Essential for Protection against both Oxidative and Nitrosative Stresses, Cell Integrity, and Normal Manifestation of Virulence Factors in the Pathogenic Fungus Cryptococcus neoformans by Gerik, Kimberly J, Bhimireddy, Sujit R, Ryerse, Jan S, Specht, Charles A, Lodge, Jennifer K

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Cross talk between the cell wall integrity and cyclic AMP/protein kinase A pathways in Cryptococcus neoformans by Donlin, Maureen J, Upadhya, Rajendra, Gerik, Kimberly J, Lam, Woei, VanArendonk, Laura G, Specht, Charles A, Sharma, Neil K, Lodge, Jennifer K

“…Cryptococcus neoformans is a fungal pathogen of immunocompromised people that causes fatal meningitis. The fungal cell wall is essential to viability and…”
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A Chitin Synthase and Its Regulator Protein Are Critical for Chitosan Production and Growth of the Fungal Pathogen Cryptococcus neoformans by Banks, Isaac R, Specht, Charles A, Donlin, Maureen J, Gerik, Kimberly J, Levitz, Stuart M, Lodge, Jennifer K

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Improvements to gene deletion in the fungal pathogen Cryptococcus neoformans: Absence of Ku proteins increases homologous recombination, and co-transformation of independent DNA molecules allows rapid complementation of deletion phenotypes by Goins, Chelsey L., Gerik, Kimberly J., Lodge, Jennifer K.

“…Cryptococcus neoformans is a pathogenic fungus that is relatively amenable to molecular genetic analysis, including gene deletion. However, rates of homologous…”
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Cryptococcus neoformans Phosphoinositide-Dependent Kinase 1 (PDK1) Ortholog Is Required for Stress Tolerance and Survival in Murine Phagocytes by Chabrier-Roselló, Yeissa, Gerik, Kimberly J, Koselny, Kristy, DiDone, Louis, Lodge, Jennifer K, Krysan, Damian J

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Cell wall integrity is dependent on the PKC1 signal transduction pathway in Cryptococcus neoformans by Gerik, Kimberly J., Donlin, Maureen J., Soto, Carlos E., Banks, Annette M., Banks, Isaac R., Maligie, Marybeth A., Selitrennikoff, Claude P., Lodge, Jennifer K.

“…Summary Cell wall biogenesis and integrity are crucial for fungal growth, pathogenesis and survival, and are attractive targets for antifungal therapy. In this…”
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Role and mechanism of phosphatidylinositol-specific phospholipase C in survival and virulence of Cryptococcus neoformans by Chayakulkeeree, Methee, Sorrell, Tania C, Siafakas, A. Rosemary, Wilson, Christabel F, Pantarat, Namfon, Gerik, Kimberly J, Boadle, Ross, Djordjevic, Julianne T

“…Phospholipase B1 (Plb1) is secreted after release from its glycosylphosphatidylinositol anchor and is implicated in initiation and dissemination of infection…”
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Cryptococcus neoformans Gene Involved in Mammalian Pathogenesis Identified by a Caenorhabditis elegans Progeny-Based Approach by Tang, Robin J, Breger, Julia, Idnurm, Alexander, Gerik, Kimberly J, Lodge, Jennifer K, Heitman, Joseph, Calderwood, Stephen B, Mylonakis, Eleftherios

“…Caenorhabditis elegans can serve as a substitute host for the study of microbial pathogenesis. We found that mutations in genes of the fungal pathogen…”
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The roles of fission yeast exonuclease 5 in nuclear and mitochondrial genome stability by Sparks, Justin L., Gerik, Kimberly J., Stith, Carrie M., Yoder, Bonita L., Burgers, Peter M.

“…•Exo5 is an understudied 5′-exonuclease that is downregulated in several cancers.•Fission yeast Exo5 is a good model system for the human enzyme.•Fission yeast…”
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KRE genes are required for β-1,6-glucan synthesis, maintenance of capsule architecture and cell wall protein anchoring in Cryptococcus neoformans by Gilbert, Nicole M, Donlin, Maureen J, Gerik, Kimberly J, Specht, Charles A, Djordjevic, Julianne T, Wilson, Christabel F, Sorrell, Tania C, Lodge, Jennifer K

“…The polysaccharide β-1,6-glucan is a major component of the cell wall of Cryptococcus neoformans, but its function has not been investigated in this fungal…”
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Overproduction and affinity purification of Saccharomyces cerevisiae replication factor C by Gerik, K.J, Gary, S.L, Burgers, P.M.J

“…Yeast replication factor C (RF-C) is a heteropentamer encoded by the RFC1-5 genes. RF-C activity in yeast extracts was overproduced about 80-fold after…”
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Destabilized PCNA Trimers Suppress Defective Rfc1 Proteins in Vivo and in Vitro by Beckwith, William H, Sun, Qiang, Bosso, Robert, Gerik, Kimberly J, Burgers, Peter M. J, McAlear, Michael A

“…Replication factor C (RFC) and the proliferating cell nuclear antigen (PCNA) are two essential DNA polymerase accessory proteins that are required for numerous…”
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Structure and Processivity of Two Forms of Saccharomyces cerevisiae DNA Polymerase δ by Burgers, Peter M.J., Gerik, Kimberly J.

“…Yeast DNA polymerase δ (Polδ) consists of three subunits encoded by the POL3, POL31, andPOL32 genes. Each of these genes was cloned under control of the…”
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Characterization of the Two Small Subunits of Saccharomyces cerevisiae DNA Polymerase δ by Gerik, Kimberly J., Li, Xiangyang, Pautz, Angela, Burgers, Peter M.J.

“…Yeast DNA polymerase δ (Polδ) has three subunits of 125, 58, and 55 kDa. The gene for the 125-kDa catalytic subunit (POL3) has been known for several years…”
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Analysis of the Genome and Transcriptome of Cryptococcus neoformans var. grubii Reveals Complex RNA Expression and Microevolution Leading to Virulence Attenuation: e1004261 by Janbon, Guilhem, Ormerod, Kate L, Paulet, Damien, Byrnes III, Edmond J, Yadav, Vikas, Chatterjee, Gautam, Mullapudi, Nandita, Hon, Chung-Chau, Billmyre, R Blake, Brunel, François, Bahn, Yong-Sun, Chen, Weidong, Chen, Yuan, Chow, Eve WL, Coppée, Jean-Yves, Floyd-Averette, Anna, Gaillardin, Claude, Gerik, Kimberly J, Goldberg, Jonathan, Gonzalez-Hilarion, Sara, Gujja, Sharvari, Hamlin, Joyce L, Hsueh, Yen-Ping, Ianiri, Giuseppe, Jones, Steven, Kodira, Chinnappa D, Kozubowski, Lukasz, Lam, Woei, Marra, Marco, Mesner, Larry D, Mieczkowski, Piotr A, Moyrand, Frédérique, Nielsen, Kirsten, Proux, Caroline, Rossignol, Tristan, Schein, Jacqueline E, Sun, Sheng, Wollschlaeger, Carolin, Wood, Ian A, Zeng, Qiandong, Neuvéglise, Cécile, Newlon, Carol S, Perfect, John R, Lodge, Jennifer K, Idnurm, Alexander, Stajich, Jason E, Kronstad, James W, Sanyal, Kaustuv, Heitman, Joseph, Fraser, James A, Cuomo, Christina A, Dietrich, Fred S

“…Cryptococcus neoformans is a pathogenic basidiomycetous yeast responsible for more than 600,000 deaths each year. It occurs as two serotypes (A and D)…”
Get full text

KRE genes are required for b-1,6-glucan synthesis, maintenance of capsule architecture and cell wall protein anchoring in Cryptococcus neoformans by Gilbert, Nicole M, Donlin, Maureen J, Gerik, Kimberly J, Specht, Charles A, Djordjevic, Julianne T, Wilson, Christabel F, Sorrell, Tania C, Lodge, Jennifer K

“…SummaryThe polysaccharide b-1,6-glucan is a major component of the cell wall of Cryptococcus neoformans, but its function has not been investigated in this…”
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KRE genes are required for [beta]-1,6-glucan synthesis, maintenance of capsule architecture and cell wall protein anchoring in Cryptococcus neoformans by Gilbert, Nicole M, Donlin, Maureen J, Gerik, Kimberly J, Specht, Charles A, Djordjevic, Julianne T, Wilson, Christabel F, Sorrell, Tania C, Lodge, Jennifer K

“…The polysaccharide β-1,6-glucan is a major component of the cell wall of Cryptococcus neoformans, but its function has not been investigated in this fungal…”
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Structure and Processivity of Two Forms of Saccharomyces cerevisiae DNA Polymerase Î by Peter M. J. Burgers, Kimberly J. Gerik

“…Yeast DNA polymerase δ (Polδ) consists of three subunits encoded by the POL3 , POL31, and POL32 genes. Each of these genes was cloned under control of the…”
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