Search Results - "Gerhartl, Anna"

The blood-brain barrier is dysregulated in COVID-19 and serves as a CNS entry route for SARS-CoV-2 by Krasemann, Susanne, Haferkamp, Undine, Pfefferle, Susanne, Woo, Marcel S., Heinrich, Fabian, Schweizer, Michaela, Appelt-Menzel, Antje, Cubukova, Alevtina, Barenberg, Janica, Leu, Jennifer, Hartmann, Kristin, Thies, Edda, Littau, Jessica Lisa, Sepulveda-Falla, Diego, Zhang, Liang, Ton, Kathy, Liang, Yan, Matschke, Jakob, Ricklefs, Franz, Sauvigny, Thomas, Sperhake, Jan, Fitzek, Antonia, Gerhartl, Anna, Brachner, Andreas, Geiger, Nina, König, Eva-Maria, Bodem, Jochen, Franzenburg, Sören, Franke, Andre, Moese, Stefan, Müller, Franz-Josef, Geisslinger, Gerd, Claussen, Carsten, Kannt, Aimo, Zaliani, Andrea, Gribbon, Philip, Ondruschka, Benjamin, Neuhaus, Winfried, Friese, Manuel A., Glatzel, Markus, Pless, Ole

“…Neurological complications are common in COVID-19. Although SARS-CoV-2 has been detected in patients’ brain tissues, its entry routes and resulting…”
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Polycomb Protein Eed is Required for Neurogenesis and Cortical Injury Activation in the Subventricular Zone by Sun, Bin, Chang, Eunhyuk, Gerhartl, Anna, Szele, Francis G

“…Abstract The postnatal subventricular zone (SVZ) harbors neural stem cells (NSCs) that exhibit robust neurogenesis. However, the epigenetic mechanisms that…”
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A Microfluidic Multisize Spheroid Array for Multiparametric Screening of Anticancer Drugs and Blood–Brain Barrier Transport Properties by Eilenberger, Christoph, Rothbauer, Mario, Selinger, Florian, Gerhartl, Anna, Jordan, Christian, Harasek, Michael, Schädl, Barbara, Grillari, Johannes, Weghuber, Julian, Neuhaus, Winfried, Küpcü, Seta, Ertl, Peter

“…Physiological‐relevant in vitro tissue models with their promise of better predictability have the potential to improve drug screening outcomes in preclinical…”
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The pivotal role of micro-environmental cells in a human blood-brain barrier in vitro model of cerebral ischemia: functional and transcriptomic analysis by Gerhartl, Anna, Pracser, Nadja, Vladetic, Alexandra, Hendrikx, Sabrina, Friedl, Heinz-Peter, Neuhaus, Winfried

“…The blood-brain barrier (BBB) is altered in several diseases of the central nervous system. For example, the breakdown of the BBB during cerebral ischemia in…”
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Transport of Non-Steroidal Anti-Inflammatory Drugs across an Oral Mucosa Epithelium In Vitro Model by Lin, Grace C, Friedl, Heinz-Peter, Grabner, Sarah, Gerhartl, Anna, Neuhaus, Winfried

“…Non-steroidal anti-inflammatory drugs (NSAIDs) are one of the most prescribed drugs to treat pain or fever. However, oral administration of NSAIDs is…”
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A Human Stem Cell-Derived Brain-Liver Chip for Assessing Blood-Brain-Barrier Permeation of Pharmaceutical Drugs by Koenig, Leopold, Ramme, Anja Patricia, Faust, Daniel, Mayer, Manuela, Flötke, Tobias, Gerhartl, Anna, Brachner, Andreas, Neuhaus, Winfried, Appelt-Menzel, Antje, Metzger, Marco, Marx, Uwe, Dehne, Eva-Maria

“…Significant advancements in the field of preclinical in vitro blood-brain barrier (BBB) models have been achieved in recent years, by developing…”
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Human isogenic cells of the neurovascular unit exert transcriptomic cell type-specific effects on a blood-brain barrier in vitro model of late-onset Alzheimer disease by Haferkamp, Undine, Hartmann, Carla, Abid, Chaudhry Luqman, Brachner, Andreas, Höchner, Alevtina, Gerhartl, Anna, Harwardt, Bernadette, Leckzik, Selin, Leu, Jennifer, Metzger, Marco, Nastainczyk-Wulf, Marina, Neuhaus, Winfried, Oerter, Sabrina, Pless, Ole, Rujescu, Dan, Jung, Matthias, Appelt-Menzel, Antje

“…Abstract Background The function of the blood-brain barrier (BBB) is impaired in late-onset Alzheimer disease (LOAD), but the associated molecular mechanisms,…”
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Hydroxyethylstarch (130/0.4) tightens the blood-brain barrier in vitro by Gerhartl, Anna, Hahn, Kathrin, Neuhoff, Anja, Friedl, Heinz-Peter, Förster, Carola Y., Wunder, Christian, Schick, Martin, Burek, Malgorzata, Neuhaus, Winfried

“…•Hydroxyethylstarch (130/0.4) modulated cell viability of brain endothelial cells.•Hydroxyethylstarch (130/0.4) increased expression of tight junction…”
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