Search Results - "Gergei, Ingrid"
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Cardiovascular risk algorithms in primary care: Results from the DETECT study
Published in Scientific reports (31-01-2019)“…Guidelines for prevention of cardiovascular diseases use risk scores to guide the intensity of treatment. A comparison of these scores in a German population…”
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Author Correction: Cardiovascular risk algorithms in primary care: Results from the DETECT study
Published in Scientific reports (31-03-2020)“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Circulating Sclerostin Levels Are Positively Related to Coronary Artery Disease Severity and Related Risk Factors
Published in Journal of bone and mineral research (01-02-2022)“…ABSTRACT Romosozumab is a newly available treatment for osteoporosis acting by sclerostin inhibition. Its cardiovascular safety has been questioned after…”
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Efficacy of Empagliflozin in Patients With Heart Failure Across Kidney Risk Categories
Published in Journal of the American College of Cardiology (16-05-2023)“…Empagliflozin reduces the risk of major heart failure outcomes in heart failure with reduced or preserved ejection fraction. The goal of this study was to…”
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Renal function, N-terminal Pro-B-Type natriuretic peptide, propeptide big-endothelin and patients with heart failure and preserved ejection fraction
Published in Peptides (New York, N.Y. : 1980) (01-01-2019)“…•NT-proBNP is strongly associated with GFR.•Three different cut-off values for NT-proBNP may be needed for the diagnosis of HFpEF in CKD patients.•Big-ET-1 is…”
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Association of soluble CD40L with short-term and long-term cardiovascular and all-cause mortality: The Ludwigshafen Risk and Cardiovascular Health (LURIC) study
Published in Atherosclerosis (01-12-2019)“…The CD40−CD40 Ligand (CD40L) system has an important role in vascular inflammation. For this reason, we assessed the association of soluble CD40L with…”
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Lowering of Circulating Sclerostin May Increase Risk of Atherosclerosis and Its Risk Factors: Evidence From a Genome-Wide Association Meta-Analysis Followed by Mendelian Randomization
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-10-2023)“…In this study, we aimed to establish the causal effects of lowering sclerostin, target of the antiosteoporosis drug romosozumab, on atherosclerosis and its…”
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GWAS meta-analysis followed by Mendelian randomization revealed potential control mechanisms for circulating α-Klotho levels
Published in Human molecular genetics (03-03-2022)“…Abstract The protein α-Klotho acts as transmembrane co-receptor for fibroblast growth factor 23 (FGF23) and is a key regulator of phosphate homeostasis…”
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Efficacy and Safety of Dabigatran in the Treatment and Secondary Prophylaxis of Children with Venous Thromboembolism and Thrombophilia
Published in Blood (05-11-2020)“…Background: Thrombophilia in children is characterized by hypercoagulability and increased frequency of thrombotic events (Young G, et al. Circulation…”
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Familial hypercholesterolemia in primary care in Germany. Diabetes and cardiovascular risk evaluation: Targets and Essential Data for Commitment of Treatment (DETECT) study
Published in Atherosclerosis (01-11-2017)“…Familial hypercholesterolemia (FH) is an inherited disorder of lipoprotein metabolism characterised by impaired removal of low-density lipoproteins (LDL) from…”
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Mendelian Randomization Analysis Reveals a Causal Influence of Circulating Sclerostin Levels on Bone Mineral Density and Fractures
Published in Journal of bone and mineral research (01-10-2019)“…ABSTRACT In bone, sclerostin is mainly osteocyte‐derived and plays an important local role in adaptive responses to mechanical loading. Whether circulating…”
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Platelet and Monocyte Activity Markers and Mortality in Patients with End-Stage Renal Disease
Published in Clinical laboratory (Heidelberg) (01-01-2020)“…The association of platelet and monocyte activity markers with long-term mortality was assessed in hemodialysis (HD) patients. In 41 HD patients (25 male, 16…”
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Propeptide big-endothelin, N-terminal-pro brain natriuretic peptide and mortality. The Ludwigshafen risk and cardiovascular health (LURIC) study
Published in Biomarkers (19-05-2017)“…Context: The endothelin system (Big-ET-1) is a key regulator in cardiovascular (CV) disease and congestive heart failure (CHF). Objectives: We have examined…”
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Chronic kidney disease in primary care in Germany
Published in Journal of public health (01-04-2017)“…Aims The continuing growth of the population with end-stage renal disease (ESRD) in the past two decades has been recognized as a global health burden. In…”
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