Search Results - "Gere, Aniko"

Nitrone derivatives of trolox as neuroprotective agents by Balogh, György T., Vukics, Krisztina, Könczöl, Árpád, Kis-Varga, Ágnes, Gere, Anikó, Fischer, János

“…Synthesis of nitrone derivatives of trolox 2 is described. Their biological evaluation was performed in vitro for scavenging different free radicals,…”
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Oxamides as novel NR2B selective NMDA receptor antagonists by Barta-Szalai, Gizella, Borza, István, Bozó, Éva, Kiss, Csilla, Ágai, Béla, Proszenyák, Ágnes, Keserű, György M, Gere, Anikó, Kolok, Sándor, Galgóczy, Kornél, Horváth, Csilla, Farkas, Sándor, Domány, György

“…Compounds of general formula A with potent p.o. analgesic activity were prepared. W=O or S; X=O, S, NH, CH 2, CH 2O or OCH 2; Y=CH 2 or O; Z=H, F, Cl or CH 3…”
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Indole-2-carboxamides as novel NR2B selective NMDA receptor antagonists by BORZA, Istvan, KOLOK, Sandor, BIELIK, Attila, NAGY, Jozsef, FARKAS, Sandor, DOMANY, György, GERE, Aniko, AGAI-CSONGOR, Eva, AGAI, Béla, TARKANYI, Gabor, HORVATH, Csilla, BARTA-SZALAI, Gizella, BOZO, Eva, KISS, Csilla

“…A novel series of indole-2-carboxamide derivatives was prepared and identified as NR2B selective NMDA receptor antagonists. The influence of the number and…”
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The influence of 5-HT2A activity on a 5-HT2C specific in vivo assay used for early identification of multiple acting SERT and 5-HT2C receptor ligands by Éliás, Olivér, Nógrádi, Katalin, Domány, György, Szakács, Zoltán, Kóti, János, Szántay, Csaba, Tarcsay, Ákos, Keserű, György M., Gere, Anikó, Kiss, Béla, Kurkó, Dalma, Kolok, Sándor, Némethy, Zsolt, Kapui, Zoltán, Hellinger, Éva, Vastag, Mónika, Sághy, Katalin, Kedves, Rita, Gyertyán, István

“…[Display omitted] As a result of our exploratory programme aimed at elaborating dually acting compounds towards the serotonin (5-HT) transporter (SERT) and the…”
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Design of novel multiple-acting ligands towards SERT and 5-HT2C receptors by Éliás, Olivér, Ágai-Csongor, Éva, Domány, György, Keserű, György Miklós, Gere, Anikó, Kiss, Béla, Hellinger, Éva, Vastag, Mónika, Gyertyán, István

“…This Letter describes our attempts to elaborate dually acting compounds possessing serotonin re-uptake transporter inhibitor and serotonin 5-HT2C receptor…”
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Discovery of Novel Histamine H4 and Serotonin Transporter Ligands Using the Topological Feature Tree Descriptor by Kiss, Róbert, Sándor, Márk, Gere, Anikó, Schmidt, Éva, Balogh, György T, Kiss, Béla, Molnár, László, Lemmen, Christian, Keserű, György M

“…Ligand-based approaches are particularly important in the hit identification process of drug discovery when no structural information on the target is…”
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Tolperisone-type drugs inhibit spinal reflexes via blockade of voltage-gated sodium and calcium channels by Kocsis, Pál, Farkas, Sándor, Fodor, László, Bielik, Norbert, Thán, Márta, Kolok, Sándor, Gere, Anikó, Csejtei, Mónika, Tarnawa, István

“…The spinal reflex depressant mechanism of tolperisone and some of its structural analogs with central muscle relaxant action was investigated. Tolperisone…”
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Kynurenic acid amides as novel NR2B selective NMDA receptor antagonists by Borza, István, Kolok, Sándor, Galgóczy, Kornél, Gere, Anikó, Horváth, Csilla, Farkas, Sándor, Greiner, István, Domány, György

“…Starting from indole- and benzimidazole-2-carboxamides as lead compounds, a novel series of kynurenic acid amide derivatives was prepared and identified as…”
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Synthesis and Evaluation of 2′-Hydroxyethyl trans-Apovincaminate Derivatives as Antioxidant and Cognitive Enhancer Agents by Nemes, András, Czibula, László, Szántay, Jr, Csaba, Gere, Anikó, Kiss, Béla, Laszy, Judit, Gyertyán, István, Szombathelyi, Zsolt, Szántay, Csaba

“…A series of trans-2′-hydroxyethyl and 2′-acyloxyethyl apovincaminates 4b−f and 7b−f has been synthesized and evaluated for their antioxidant and antiamnesic…”
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Selective NR1/2B N-Methyl-d-aspartate Receptor Antagonists among Indole-2-carboxamides and Benzimidazole-2-carboxamides by Borza, István, Bozó, Éva, Barta-Szalai, Gizella, Kiss, Csilla, Tárkányi, Gábor, Demeter, Ádám, Gáti, Tamás, Háda, Viktor, Kolok, Sándor, Gere, Anikó, Fodor, László, Nagy, József, Galgóczy, Kornél, Magdó, Ildikó, Ágai, Béla, Fetter, József, Bertha, Ferenc, Keserü, György M, Horváth, Csilla, Farkas, Sándor, Greiner, István, Domány, György

“…(4-Benzylpiperidine-1-yl)-(6-hydroxy-1H-indole-2-yl)-methanone (6a) derived from (E)-1-(4-benzylpiperidin-1-yl)-3-(4-hydroxy-phenyl)-propenone (5) was…”
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Chemical and biological investigation of N-hydroxy-valdecoxib: An active metabolite of valdecoxib by Erdélyi, Péter, Fodor, Tamás, Varga, Ágnes Kis, Czugler, Mátyás, Gere, Anikó, Fischer, János

“…The inhibition of cyclooxygenase enzymes plays an important role in the treatment of inflammatory diseases…”
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Design of novel multiple-acting ligands towards SERT and 5-HT sub(2C) receptors by Elias, Oliver, Agai-Csongor, Eva, Domany, Gyorgy, Keserue, Gyorgy Miklos, Gere, Aniko, Kiss, Bela, Hellinger, Eva, Vastag, Monika, Gyertyan, Istvan

“…This Letter describes our attempts to elaborate dually acting compounds possessing serotonin re-uptake transporter inhibitor and serotonin 5-HT sub(2C)…”
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The influence of 5-HT sub(2A) activity on a 5-HT sub(2C) specific in vivo assay used for early identification of multiple acting SERT and 5-HT sub(2C) receptor ligands by Elias, Oliver, Nogradi, Katalin, Domany, Gyorgy, Szakacs, Zoltan, Koti, Janos, Szantay, Csaba Jr, Tarcsay, Akos, Keserue, Gyorgy M, Gere, Aniko, Kiss, Bela, Kurko, Dalma, Kolok, Sandor, Nemethy, Zsolt, Kapui, Zoltan, Hellinger, Eva, Vastag, Monika, Saghy, Katalin, Kedves, Rita, Gyertyan, Istvan

“…As a result of our exploratory programme aimed at elaborating dually acting compounds towards the serotonin (5-HT) transporter (SERT) and the 5-HT sub(2C)…”
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Benzimidazole-2-carboxamides as novel NR2B selective NMDA receptor antagonists by Borza, István, Kolok, Sándor, Gere, Anikó, Nagy, József, Fodor, László, Galgóczy, Kornél, Fetter, József, Bertha, Ferenc, Ágai, Béla, Horváth, Csilla, Farkas, Sándor, Domány, György

“…A novel series of benzimidazole-2-carboxamide derivatives was prepared and identified as NR2B selective NMDA receptor antagonists. The influence of some…”
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Comparative pharmacology of adrenergic alpha sub(2C) receptors coupled to Ca super(2+) signaling through different G alpha proteins by Kurko, Dalma, Bekes, Zsofia, Gere, Aniko, Baki, Andrea, Boros, Andras, Kolok, Sandor, Bugovics, Gyula, Nagy, Jozsef, Szombathelyi, Zsolt, Ignacz-Szendrei, Gyoergyi

“…Adrenergic alpha sub(1), alpha sub(2) and beta receptors are members of the G-protein-coupled receptor families (GPCRs) mediating physiological responses to…”
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Synthesis and studies of 1,2-dihydroquinoline derivatives as inhibitors of lipid peroxidation by BARTA-SZALAI, Gizella, GERE, Aniko, TAKACS-NOVAK, Krisztina, DOMANY, György

“…A series of new spiro[naphto[2,1-c][2,7]naphtiridine-5,4'-piperidine] derivatives was prepared. Biochemical investigations revealed that all members of this…”
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The influence of 5-HT 2A activity on a 5-HT 2C specific in vivo assay used for early identification of multiple acting SERT and 5-HT 2C receptor ligands by Éliás, Olivér, Nógrádi, Katalin, Domány, György, Szakács, Zoltán, Kóti, János, Szántay, Csaba, Tarcsay, Ákos, Keserű, György M., Gere, Anikó, Kiss, Béla, Kurkó, Dalma, Kolok, Sándor, Némethy, Zsolt, Kapui, Zoltán, Hellinger, Éva, Vastag, Mónika, Sághy, Katalin, Kedves, Rita, Gyertyán, István

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Inhibition of lipid peroxidation of herbal extracts (obtained from plant drug mixtures of Myrtilli folium, Phaseoli fructus sine seminibus and Salviae folium) used in type 2 diabetes mellitus by Szentmihályi, Klára, Gere, Anikó, Szöllosi-Varga, Ilona, Blázovics, Anna, Jasztrab, S, Ladó, Krisztina, Then, Mária

“…Plant drug mixtures are widely used in the adjuvant therapy of type 2 diabetes mellitus for the prevention of complications. The drug mixtures generally…”
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Effect of different metal ions on the oxidative damage and antioxidant capacity of hyaluronic acid by Balogh, György T., Illés, János, Székely, Zsuzsanna, Forrai, Erika, Gere, Anikó

“…Degradation and the antioxidative effect of Na–, Zn–, Co–, Cu–, and Mn–hyaluronic acid (HA) associates were studied. Our findings revealed the protective…”
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Discovery of cariprazine (RGH-188): A novel antipsychotic acting on dopamine D3/D2 receptors by Ágai-Csongor, Éva, Domány, György, Nógrádi, Katalin, Galambos, János, Vágó, István, Keserű, György Miklós, Greiner, István, Laszlovszky, István, Gere, Anikó, Schmidt, Éva, Kiss, Béla, Vastag, Mónika, Tihanyi, Károly, Sághy, Katalin, Laszy, Judit, Gyertyán, István, Zájer-Balázs, Mária, Gémesi, Larisza, Kapás, Margit, Szombathelyi, Zsolt

“…Cariprazine, a potential atypical antipsychotic agent has been identified during the optimization of novel series of 4-aryl-piperazine derivatives. The…”
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