Search Results - "Gerdes, A.Martin"
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Differentiation of human adipose tissue stem cells using extracts of rat cardiomyocytes
Published in Biochemical and biophysical research communications (06-02-2004)“…We report the differentiation of human adipose tissue stem cells (ATSCs) to take on cardiomyocyte properties following transient exposure to a rat…”
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Desmin filaments and cardiac disease: Establishing causality
Published in Journal of cardiac failure (01-12-2002)“…Background: Gene targeting studies indicate that desmin is not required for embryonic myogenesis and heart formation but is essential for maintaining the…”
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Chronic Pressure Overload Cardiac Hypertrophy and Failure in Guinea Pigs: II. Cytoskeletal Remodeling
Published in Journal of molecular and cellular cardiology (01-02-1999)“…The cytoskeleton is a major regulator of cell shape. To explore potential mechanisms for maladaptation of cardiac myocyte shape in pressure overload-induced…”
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Formation of Binucleated Cardiac Myocytes in Rat Heart: I. Role of Actin–myosin Contractile Ring
Published in Journal of molecular and cellular cardiology (01-06-1997)“…Cardiac myocytes in rat hearts lose their ability to undergo cytokinesis between day 3 and day 4, resulting in the formation of binucleated myocytes. Failure…”
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Correlation of Myocyte Lengthening to Chamber Dilation in the Spontaneously Hypertensive Heart Failure (SHHF) Rat
Published in Journal of molecular and cellular cardiology (01-11-1998)“…Chronic congestive heart failure of various etiologies is characterized by progressive chamber dilation. Although myocyte lengthening is involved, it is not…”
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Chronic Pressure Overload Cardiac Hypertrophy and Failure in Guinea Pigs: I. Regional Hemodynamics and Myocyte Remodeling
Published in Journal of molecular and cellular cardiology (01-02-1999)“…A chronic pressure overload animal model was created in young guinea pigs by surgical constriction of the descending thoracic aorta. Hemodynamics,…”
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New method to evaluate myocyte remodeling from formalin-fixed biopsy and autopsy material
Published in Journal of cardiac failure (01-12-1998)“…Background: Excessive lengthening of cardiac myocytes attributed to series addition of sarcomeres is a consistent feature of left ventricular dilation in…”
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Cardiac myocyte remodeling in hypertrophy and progression to failure
Published in Journal of cardiac failure (01-12-2002)“…Contracting myocytes are highly variable in size and generally resemble elliptical cylinders in shape. Although their arrangement within the ventricular wall…”
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Rapid Transition of Cardiac Myocytes from Hyperplasia to Hypertrophy During Postnatal Development
Published in Journal of molecular and cellular cardiology (01-08-1996)“…The switch from myocyte hyperplasia to hypertrophy occurs during the early postnatal period. The exact temporal sequence when cardiac myocytes cease dividing…”
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Chronic Pressure Overload Cardiac Hypertrophy and Failure in Guinea Pigs: III. Intercalated Disc Remodeling
Published in Journal of molecular and cellular cardiology (01-02-1999)“…The intercalated disc is an extremely important specialised structure of cardiac muscle. Intercalated disc alterations have been implicated in ischemic and…”
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14 Integrin alterations during LV myocyte remodeling in spontaneously hypertensive heart failure (SHHF) rats
Published in Journal of molecular and cellular cardiology (01-07-2002)Get full text
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Structural remodeling and mechanical dysfunction of cardiac myocytes in heart failure
Published in Journal of Molecular and Cellular Cardiology (01-03-1995)“…End stage heart failure due to ischemic (ICM) or dilated (DCM) cardiomyopathy is characterized by a dilated, relatively thin-walled ventricle. The hypothesis…”
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Book Review Journal Article -
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Formation of Binucleated Cardiac Myocytes in Rat Heart: II. Cytoskeletal Organisation
Published in Journal of molecular and cellular cardiology (01-06-1997)“…Formation of Binucleated Cardiac Myocytes in Rat Heart: II. Cytoskeletal Organisation.Journal of Molecular and Cellular Cardiology(1997)29, 1553–1565. Neonatal…”
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Remodeling of the Intercalated Disks in Desmin-Related Cardiomyopathy Caused by an αB-Crystallin Mutation in Mice
Published in Journal of cardiac failure (01-10-2003)Get full text
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20 Expression of R120G-αB-crystallin impairs proteolytic function of the proteasomes
Published in Journal of molecular and cellular cardiology (01-07-2002)Get full text
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Regional Myocyte Hypertrophy Parallels Regional Myocardial Dysfunction During Post-infarct Remodeling
Published in Journal of molecular and cellular cardiology (01-09-1998)“…After large myocardial infarction (MI), left-ventricular (LV) remodeling is characterized by cavity dilatation, eccentric hypertrophy, and regional mechanical…”
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A reliable, efficient, and comprehensive approach to assess myocyte remodeling in cardiac hypertrophy and failure
Published in Journal of cardiac failure (01-03-1997)“…Interest in ventricular remodeling has increased in recent years due to the development of new therapeutic agents which may produce beneficial changes in…”
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Journal Article -
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Adding angiotensin II type 1 receptor blockade to angiotensin-converting enzyme inhibition limits myocyte remodeling after myocardial infarction
Published in Journal of cardiac failure (01-06-2003)“…Background: Adding angiotensin II type 1 receptor blockade (ARB) to angiotensin-converting enzyme inhibition (ACEI) further attenuates left ventricular (LV)…”
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