Search Results - "Gerckens, Michael"

The instructive extracellular matrix of the lung: basic composition and alterations in chronic lung disease by Burgstaller, Gerald, Oehrle, Bettina, Gerckens, Michael, White, Eric S, Schiller, Herbert B, Eickelberg, Oliver

“…The pulmonary extracellular matrix (ECM) determines the tissue architecture of the lung, and provides mechanical stability and elastic recoil, which are…”
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Preoperative risk factors predict perioperative allogenic blood transfusion in patients undergoing primary lung cancer resections: a retrospective cohort study from a high-volume thoracic surgery center by Stoleriu, Mircea Gabriel, Gerckens, Michael, Zimmermann, Julia, Schön, Johannes, Damirov, Fuad, Samm, Nicole, Kovács, Julia, Stacher-Priehse, Elvira, Kellerer, Christina, Jörres, Rudolf A, Kauke, Teresa, Ketscher, Christian, Grützner, Uwe, Hatz, Rudolf

“…Our study aimed to identify preoperative predictors for perioperative allogenic blood transfusion (ABT) in patients undergoing major lung cancer resections in…”
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Spirometrie zeigt COPD früher an als gedacht by Kahnert, Kathrin, Gerckens, Michael

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Characterization of Baseline Lung Allograft Dysfunction in Single Lung Transplant Recipients by Gerckens, Michael, Mümmler, Carlo, Richard, Alexander, Strodel, Johannes, Mertsch, Pontus, Milger, Katrin, Veit, Tobias, Gade, Nils, Yildirim, Ali Önder, Schneider, Christian, Kauke, Teresa, Michel, Sebastian, Irlbeck, Michael, Behr, Jürgen, Kneidinger, Nikolaus

“…Baseline lung allograft dysfunction (BLAD) is characterized by the failure to achieve normal baseline lung function after double lung transplantation (DLTX)…”
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Reversible Atemwegsobstruktion als potenzieller Prädiktor eines COPD-Verlaufs? by Kahnert, Kathrin, Gerckens, Michael

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Generation of Human 3D Lung Tissue Cultures (3D-LTCs) for Disease Modeling by Gerckens, Michael, Alsafadi, Hani N, Wagner, Darcy E, Lindner, Michael, Burgstaller, Gerald, Königshoff, Melanie

“…Translation of novel discoveries to human disease is limited by the availability of human tissue-based models of disease. Precision-cut lung slices (PCLS) used…”
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COPD basal cells are primed towards secretory to multiciliated cell imbalance driving increased resilience to environmental stressors by Stoleriu, Mircea Gabriel, Ansari, Meshal, Strunz, Maximilian, Schamberger, Andrea, Heydarian, Motaharehsadat, Ding, Yaobo, Voss, Carola, Schneider, Juliane Josephine, Gerckens, Michael, Burgstaller, Gerald, Castelblanco, Alejandra, Kauke, Teresa, Fertmann, Jan, Schneider, Christian, Behr, Juergen, Lindner, Michael, Stacher-Priehse, Elvira, Irmler, Martin, Beckers, Johannes, Eickelberg, Oliver, Schubert, Benjamin, Hauck, Stefanie M, Schmid, Otmar, Hatz, Rudolf A, Stoeger, Tobias, Schiller, Herbert B, Hilgendorff, Anne

“…Environmental pollutants injure the mucociliary elevator, thereby provoking disease progression in chronic obstructive pulmonary disease (COPD). Epithelial…”
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Sfrp1 inhibits lung fibroblast invasion during transition to injury-induced myofibroblasts by Mayr, Christoph H, Sengupta, Arunima, Asgharpour, Sara, Ansari, Meshal, Pestoni, Jeanine C, Ogar, Paulina, Angelidis, Ilias, Liontos, Andreas, Rodriguez-Castillo, José Alberto, Lang, Niklas J, Strunz, Maximilian, Porras-Gonzalez, Diana, Gerckens, Michael, De Sadeleer, Laurens J, Oehrle, Bettina, Viteri-Alvarez, Valeria, Fernandez, Isis E, Tallquist, Michelle, Irmler, Martin, Beckers, Johannes, Eickelberg, Oliver, Stoleriu, Gabriel Mircea, Behr, Jürgen, Kneidinger, Nikolaus, Wuyts, Wim A, Wasnick, Roxana Maria, Yildirim, Ali Önder, Ahlbrecht, Katrin, Morty, Rory E, Samakovlis, Christos, Theis, Fabian J, Burgstaller, Gerald, Schiller, Herbert B

“…Fibroblast-to-myofibroblast conversion is a major driver of tissue remodelling in organ fibrosis. Distinct lineages of fibroblasts support homeostatic tissue…”
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Clinical Course of Three Postoperative Symptomatic COVID-19 Cases in Patients After Lung Lobectomy by Stoleriu, Mircea Gabriel, Gerckens, Michael, Hetrodt, Justin, Heiß-Neumann, Marion, Koch, Ina, Stacher-Priehse, Elvira, Dinkel, Julien, Behr, Jürgen, Grützner, Uwe, Hatz, Rudolf

“…The novel coronavirus disease 2019 is a highly contagious viral infection caused by the severe acute respiratory syndrome coronavirus 2 virus. Its rapid spread…”
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Ex vivo tissue perturbations coupled to single-cell RNA-seq reveal multilineage cell circuit dynamics in human lung fibrogenesis by Lang, Niklas J, Gote-Schniering, Janine, Porras-Gonzalez, Diana, Yang, Lin, De Sadeleer, Laurens J, Jentzsch, R Christoph, Shitov, Vladimir A, Zhou, Shuhong, Ansari, Meshal, Agami, Ahmed, Mayr, Christoph H, Hooshiar Kashani, Baharak, Chen, Yuexin, Heumos, Lukas, Pestoni, Jeanine C, Molnar, Eszter Sarolta, Geeraerts, Emiel, Anquetil, Vincent, Saniere, Laurent, Wögrath, Melanie, Gerckens, Michael, Lehmann, Mareike, Yildirim, Ali Önder, Hatz, Rudolf, Kneidinger, Nikolaus, Behr, Jürgen, Wuyts, Wim A, Stoleriu, Mircea-Gabriel, Luecken, Malte D, Theis, Fabian J, Burgstaller, Gerald, Schiller, Herbert B

“…Pulmonary fibrosis develops as a consequence of failed regeneration after injury. Analyzing mechanisms of regeneration and fibrogenesis directly in human…”
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Prevention of COVID-19 in Thoracic Surgery Patients: Lessons Learned during the First Pandemic Wave by Stoleriu, Mircea Gabriel, Gerckens, Michael, Ströh, Katja, Kovács, Julia, Samm, Nicole, Obereisenbuchner, Florian, Hetrodt, Justin, Schmidt, Felicitas Maria, Reinmuth, Niels, Heiß-Neumann, Marion, Stacher-Priehse, Elvira, Koch, Ina, Behr, Jürgen, Ketscher, Christian, Grützner, Uwe, Hatz, Rudolf

“…The aim of this retrospective study was to investigate the implementation of measures to prevent perioperative COVID-19 in thoracic surgery during the first…”
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Automated quantitative thin slice volumetric low dose CT analysis predicts disease severity in COVID-19 patients by Stoleriu, Mircea Gabriel, Gerckens, Michael, Obereisenbuchner, Florian, Zaimova, Iva, Hetrodt, Justin, Mavi, Sarah-Christin, Schmidt, Felicitas, Schoenlebe, Anna Auguste, Heinig-Menhard, Katharina, Koch, Ina, Jörres, Rudolf A, Spiro, Judith, Nowak, Lorenz, Hatz, Rudolf, Behr, Jürgen, Gesierich, Wolfgang, Heiß-Neumann, Marion, Dinkel, Julien

“…This study aimed to identify predictive (bio-)markers for COVID-19 severity derived from automated quantitative thin slice low dose volumetric CT analysis,…”
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Phenotypic drug screening in a human fibrosis model identified a novel class of antifibrotic therapeutics by Gerckens, Michael, Schorpp, Kenji, Pelizza, Francesco, Wögrath, Melanie, Reichau, Kora, Ma, Huilong, Dworsky, Armando-Marco, Sengupta, Arunima, Stoleriu, Mircea Gabriel, Heinzelmann, Katharina, Merl-Pham, Juliane, Irmler, Martin, Alsafadi, Hani N, Trenkenschuh, Eduard, Sarnova, Lenka, Jirouskova, Marketa, Frieß, Wolfgang, Hauck, Stefanie M, Beckers, Johannes, Kneidinger, Nikolaus, Behr, Jürgen, Hilgendorff, Anne, Hadian, Kamyar, Lindner, Michael, Königshoff, Melanie, Eickelberg, Oliver, Gregor, Martin, Plettenburg, Oliver, Yildirim, Ali Önder, Burgstaller, Gerald

“…Fibrogenic processes instigate fatal chronic diseases leading to organ failure and death. Underlying biological processes involve induced massive deposition of…”
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