Search Results - "Gerbi, Susan A"

Characterizing and controlling intrinsic biases of lambda exonuclease in nascent strand sequencing reveals phasing between nucleosomes and G-quadruplex motifs around a subset of human replication origins by Foulk, Michael S, Urban, John M, Casella, Cinzia, Gerbi, Susan A

“…Nascent strand sequencing (NS-seq) is used to discover DNA replication origins genome-wide, allowing identification of features for their specification. NS-seq…”
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Bundling up DNA by Gerbi, Susan A

“…Structures known as chromocenters, comprising satellite DNA and proteins such as D1 or HMGA1, help to contain DNA inside the nucleus between cell divisions…”
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High contiguity de novo genome assembly and DNA modification analyses for the fungus fly, Sciara coprophila, using single-molecule sequencing by Urban, John M, Foulk, Michael S, Bliss, Jacob E, Coleman, C Michelle, Lu, Nanyan, Mazloom, Reza, Brown, Susan J, Spradling, Allan C, Gerbi, Susan A

“…The lower Dipteran fungus fly, Sciara coprophila, has many unique biological features that challenge the rule of genome DNA constancy. For example, Sciara…”
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Donald D. Brown, groundbreaking embryologist (1931–2023) by Gerbi, Susan A.

“…Molecular biologist whose work on isolated genes helped launch the era of recombinant DNA and gene editing. Molecular biologist whose work on isolated genes…”
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Non-random chromosome segregation and chromosome eliminations in the fly Bradysia (Sciara) by Gerbi, Susan A.

“…Mendelian inheritance is based upon random segregation of homologous chromosomes during meiosis and perfect duplication and division of chromosomes in mitosis…”
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Whole Organism Genome Editing: Targeted Large DNA Insertion via ObLiGaRe Nonhomologous End-Joining in Vivo Capture by Yamamoto, Yutaka, Bliss, Jacob, Gerbi, Susan A

“…Targeted gene insertion is a goal of genome editing and has been performed in cultured cells but only in a handful of whole organisms. The existing method to…”
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Laboratory Maintenance of the Lower Dipteran Fly Bradysia (Sciara) coprophila: A New/Old Emerging Model Organism by Gerbi, Susan A

“…Laboratory stocks of the lower dipteran fly, Bradysia (Sciara) coprophila, have been maintained for over a century. Protocols for laboratory upkeep of B…”
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Mary-Lou Pardue (1933 to 2024): Investigating chromosomes and genomes by in situ hybridization by Gerbi, Susan A, Spradling, Allan C

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Making ends meet: targeted integration of DNA fragments by genome editing by Yamamoto, Yutaka, Gerbi, Susan A.

“…Targeted insertion of large pieces of DNA is an important goal of genetic engineering. However, this goal has been elusive since classical methods for…”
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The hunt for origins of DNA replication in multicellular eukaryotes by Urban, John M, Foulk, Michael S, Casella, Cinzia, Gerbi, Susan A

“…Origins of DNA replication (ORIs) occur at defined regions in the genome. Although DNA sequence defines the position of ORIs in budding yeast, the factors for…”
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Joseph G. Gall (1928–2024): Cell biologist, naturalist, and mentor extraordinaire by Gerbi, Susan A., Zakian, Virginia A., Blackburn, Elizabeth H.

“…Joseph Grafton Gall (1928–2024), a founder of modern cell biology, made foundational discoveries on eukaryotic chromosomes and RNA biogenesis. His major…”
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Treasure Your Exceptions: An Interview with 2017 George Beadle Award Recipient Susan A. Gerbi by Gerbi, Susan A

“…THE Genetics Society of America's (GSA) George W. Beadle Award honors individuals who have made outstanding contributions to the community of genetics…”
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Correction: Yamamoto, Y.; Gerbi, S.A. Development of Transformation for Genome Editing of an Emerging Model Organism. Genes 2022, 13 , 1108 by Yamamoto, Yutaka, Gerbi, Susan A

“…There was a typographical error in the original publication [...]…”
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Development of Transformation for Genome Editing of an Emerging Model Organism by Yamamoto, Yutaka, Gerbi, Susan A

“…With the advances in genomic sequencing, many organisms with novel biological properties are ripe for use as emerging model organisms. However, to make full…”
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The path from student to mentor and from chromosomes to replication to genomics by Gerbi, Susan A

“…The American Society for Cell Biology Women in Cell Biology Sandra Masur Senior Award recognizes leadership in scientific accomplishments and in mentoring,…”
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Beginning at the end: DNA replication within the telomere by Gerbi, Susan A

“…Using single molecule analysis of replicated DNA (SMARD), Drosopoulos et al. (2015; J. Cell Biol. http://dx.doi.org/10.1083/jcb.201410061) report that DNA…”
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The Nucleus by Gerbi, Susan A.

“…The year 2010 marked the 300th anniversary of Antony van Leeuwenhoeck's description of amphibian and avian nuclei. The field is now poised to enter a new realm…”
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William R. Brinkley: A giant in biomedical research and public policy by Gerbi, Susan A., Palazzo, Robert E., Earnshaw, William C., Schrader, William T.

“…Susan A. Gerbi, Robert E. Palazzo, William C. Earnshaw, and William T. Schrader discuss the life and achievements of William R. Brinkley, who passed away on…”
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Bradysia (Sciara) coprophila larvae up-regulate DNA repair pathways and down-regulate developmental regulators in response to ionizing radiation by Urban, John M, Bateman, Jack R, Garza, Kodie R, Borden, Julia, Jain, Jaison, Brown, Alexia, Thach, Bethany J, Bliss, Jacob E, Gerbi, Susan A

“…Abstract The level of resistance to radiation and the developmental and molecular responses can vary between species, and even between developmental stages of…”
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All small nuclear RNAs (snRNAs) of the [U4/U6.U5] Tri-snRNP localize to nucleoli; Identification of the nucleolar localization element of U6 snRNA by Gerbi, Susan A, Lange, Thilo Sascha

“…Previously, we showed that spliceosomal U6 small nuclear RNA (snRNA) transiently passes through the nucleolus. Herein, we report that all individual snRNAs of…”
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