Search Results - "Gerard, N."
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Networks of tau distribution in Alzheimer's disease
Published in Brain (London, England : 1878) (01-02-2018)“…See Whitwell (doi:10.1093/brain/awy001) for a scientific commentary on this article. The stereotypical anatomical propagation of tau pathology is indicative of…”
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A CFTR Potentiator in Patients with Cystic Fibrosis and the G551D Mutation
Published in The New England journal of medicine (03-11-2011)“…Ivacaftor, a potentiator of CFTR, was studied in patients with cystic fibrosis (CF) who had mutations that reduced the function of the CFTR protein. Ivacaftor…”
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Clinical validity of second-generation tau PET tracers as biomarkers for Alzheimer’s disease in the context of a structured 5-phase development framework
Published in European journal of nuclear medicine and molecular imaging (2021)“…Purpose In 2017, the Geneva Alzheimer’s disease (AD) strategic biomarker roadmap initiative proposed a framework of the systematic validation AD biomarkers to…”
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4
Explainable artificial intelligence identifies an AQP4 polymorphism-based risk score associated with brain amyloid burden
Published in Neurobiology of aging (01-11-2024)“…Aquaporin-4 (AQP4) is hypothesized to be a component of the glymphatic system, a pathway for removing brain interstitial solutes like amyloid-β (Aβ). Evidence…”
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Improved Tau PET SUVR Quantification in 4-Repeat Tau Phenotypes with [ 18 F]PI-2620
Published in Journal of Nuclear Medicine (01-06-2024)“…We used a new data-driven methodology to identify a set of reference regions that enhanced the quantification of the SUV ratio of the second-generation tau…”
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A comparison of donor-acceptor pairs for genetically encoded FRET sensors: application to the Epac cAMP sensor as an example
Published in PloS one (02-04-2008)“…We recently reported on CFP-Epac-YFP, an Epac-based single polypeptide FRET reporter to resolve cAMP levels in living cells. In this study, we compared and…”
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The influence of thinning and prescribed burning on future forest fires in fire-prone regions of Europe
Published in Environmental research letters (01-05-2022)“…Abstract Climate change is expected to increase fire risk in many forested regions, posing a potential threat to forest functioning (i.e. carbon pools and…”
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Patents, meet Napster: 3D printing and the digitization of things
Published in The Georgetown law journal (01-08-2014)“…Digitization has reached things. This shift promises to alter the business and legal landscape for a range of industries. Digitization has already disrupted…”
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Zygotic vinculin is not essential for embryonic development in zebrafish
Published in PloS one (02-08-2017)“…The formation of multicellular tissues during development is governed by mechanical forces that drive cell shape and tissue architecture. Protein complexes at…”
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10
Dynamic coherent diffractive imaging using unsupervised identification of spatiotemporal constraints
Published in Optics express (23-11-2020)“…Dynamic coherent diffractive imaging (CDI) reveals the fine details of structural, chemical, and biological processes occurring at the nanoscale but imposes…”
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Assessment and monitoring of lung disease in patients with severe alpha 1 antitrypsin deficiency: a european delphi consensus of the EARCO group
Published in Respiratory research (19-08-2024)“…Currently, there is conflicting information and guidance on the effective management of Alpha 1 Antitrypsin Deficiency (AATD). Establishing a consensus of…”
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12
Neural broadening or neural attenuation? Investigating age-related dedifferentiation in the face network in a large lifespan sample
Published in The Journal of neuroscience (08-02-2012)“…Previous studies have found that cortical responses to different stimuli become less distinctive as people get older. This age-related dedifferentiation may…”
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“Commonly Estimated as One Judge”: Bushrod Washington and the Marshall Court
Published in Journal of Supreme Court history (2022)“…2 One way of understanding Johnson’s comment is that he thought that Justice Washington simply followed Chief Justice Marshall’s lead, which is consistent with…”
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Towards kilohertz synchrotron coherent diffractive imaging
Published in Journal of applied crystallography (01-06-2022)“…X‐ray coherent diffractive imaging (CDI) techniques have been applied with widespread impact to study nanoscale material properties. New fast framing detectors…”
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Dynamic X‑ray Coherent Diffraction Analysis: Bridging the Time Scales between Imaging and Photon Correlation Spectroscopy
Published in Nano letters (30-10-2024)“…The advent of diffraction limited sources and developments in detector technology opens up new possibilities for the study of materials in situ and operando…”
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Local perceptions and factors determining ecosystem services identification around two forest reserves in Northern Benin
Published in Journal of ethnobiology and ethnomedicine (03-12-2019)“…Ecosystems provide humanity with goods and services known as ecosystem services. The value of these services represents a basis for political decision-making…”
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Horizon scanning to assess the bioclimatic potential for the alien species Spodoptera eridania and its parasitoids after pest detection in West and Central Africa
Published in Pest management science (01-10-2021)“…BACKGROUND The southern armyworm (SAW) Spodoptera eridania (Stoll) (Lepidoptera: Noctuidae) is native to the tropical Americas where the pest can feed on more…”
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Uses, Cultural Importance, and Fire Threat to Pseudocedrela kotschyi (Meliaceae): Evidence for the Availability Hypothesis in Benin (West Africa)
Published in Economic botany (01-09-2023)“…Pseudocedrela kotschyi is one of the most widely exploited species in Benin. Therefore, populations of the species are faced with the issue of human…”
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REDISCOVERING CORFIELD V. CORYELL
Published in The Notre Dame law review (01-12-2019)“…Magliocca discusses the Supreme Sourt case Corfield v. Coryell. Justice Bushrod Washington's 1825 circuit opinion in Corfield v. Coryell is probably the most…”
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Clinical considerations in individuals with α1-antitrypsin PISZ genotype
Published in The European respiratory journal (01-06-2020)“…α 1 -Antitrypsin deficiency (AATD), characterised by reduced levels or functionality of α 1 -antitrypsin (AAT), is a significantly underdiagnosed genetic…”
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