Search Results - "Geraghty, J G"

Transcriptional regulation of cellular senescence by Lanigan, F, Geraghty, J G, Bracken, A P

“…Cellular senescence is an irreversible arrest of proliferation. It is activated when a cell encounters stress such as DNA damage, telomere shortening or…”
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Sentinel-node biopsy to avoid axillary dissection in breast cancer with clinically negative lymph-nodes by Veronesi, U, Paganelli, G, Galimberti, V, Viale, G, Zurrida, S, Bedoni, M, Costa, A, de Cicco, C, Geraghty, J G, Luini, A, Sacchini, V, Veronesi, P

“…Axillary lymph-node dissection is an important staging procedure in the surgical treatment of breast cancer. However, early diagnosis has led to increasing…”
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Quality control in breast cancer surgery by Birido, N, Geraghty, J G

“…Quality assurance is the process by which quality care can be assessed. The general principles include setting a standard with the aim of achieving particular…”
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Real-world analysis of clinical and economic impact of 21-gene recurrence score (RS) testing in early-stage breast cancer (ESBC) in Ireland by McSorley, L. M., Tharmabala, M., Al Rahbi, F., McSorley, K., Chew, S., Evoy, D., Geraghty, J. G., Prichard, R. S., Rothwell, J., McCartan, D. P., McDermott, E. W., Keane, M., Kennedy, M. J., O’Reilly, S., Millen, S. J., Crown, J. P., Smyth, L. M., Kelly, C. M., Quinn, C. M., Walshe, J. M.

“…Purpose Results from TAILOR-X suggest that up to 70% of hormone receptor-positive (HR+) node-negative (N0) ESBC patients (pts) may avoid chemotherapy (CT) with…”
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Oesophageal cancer treatment: Studies, strategies and facts by Wobst, A., Audisio, R. A., Colleoni, M., Geraghty, J. G.

“…Esophageal cancer is among the ten most frequent cancers in the world. Once diagnosis is established prognosis is poor with five-year survival rates below 10%…”
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Rapid assessment breast clinics – Evolution through audit by Toomey, D.P., Cahill, R.A., Birido, N., Jeffers, M., Loftus, B., McInerney, D., Rothwell, J., Geraghty, J.G.

“…This observational, cohort study aimed to examine the potential utility of Rapid Assessment Breast Clinics (RABC) beyond cancer detection at presentation. One…”
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Sentinel node localization in primary melanoma: Preoperative dynamic lymphoscintigraphy, intraoperative gamma probe, and vital dye guidance by Gennari, R., Bartolomei, M., Testori, A., Zurrida, S., Stoldt, H.S., Audisio, R.A., Geraghty, J.G., Paganelli, G., Veronesi, U.

“…Background: Sentinel node (SN) biopsy can be used to select patients with primary melanoma for therapeutic lymphadenectomy. The aim of the study was to assess…”
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Mammographic size of ductal carcinoma in situ does not predict the presence of an invasive focus by Wahedna, Y, Evans, A.J, Pinder, S.E, Ellis, I.O, Blamey, R.W, Geraghty, J.G

“…A proportion of women thought to have ductal carcinoma in situ (DCIS) on mammography and a core biopsy showing DCIS only, in fact have an invasive focus on…”
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Phenotypic analysis of familial breast cancer: Comparison of BRCAx tumors with BRCA1-, BRCA2-carriers and non-familial breast cancer by Aloraifi, F, Alshehhi, M, McDevitt, T, Cody, N, Meany, M, O'Doherty, A, Quinn, C.M, Green, A.J, Bracken, A, Geraghty, J.G

“…Abstract Aims Women with inherited pathogenic mutations in the BRCA1 or BRCA2 genes have up to an 85% risk of developing breast cancer in their lifetime…”
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Pretargeting strategies for radio-immunoguided tumour localisation and therapy by Stoldt, H.S., Aftab, F., Chinol, M., Paganelli, G., Luca, F., Testori, A., Geraghty, J.G.

“…The selective recognition of tumour cells by monoclonal antibodies, labelled with radioactive isotopes, for use in diagnosis and treatment, forms the basis of…”
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A direct relationship between thyroid enlargement and breast cancer by SMYTH, P. P. A, SMITH, D. F, MCDERMONT, E. W. M, MURRAY, M. J, GERAGHTY, J. G, O'HIGGINS, N. J

“…Despite extensive study, evidence to support a direct relationship between diseases of the thyroid and breast has not been established. In this study thyroid…”
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Sentinel node biopsy for breast cancer may have little to offer four-node-samplers: results of a prospective comparison study by Macmillan, R.D., Barbera, D., Hadjiminas, D.J., Rampaul, R.S., Lee, A.H.S., Pinder, S.E., Ellis, I.O., Blamey, R.W., Geraghty, J.G.

“…The aims of the study were to determine how often four node axillary sampling (4NAS) encompasses the sentinel node (SN) and to compare the relative sensitivity…”
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Effect of closing dead space on seroma formation after mastectomy--a prospective randomized clinical trial by Coveney, E C, O'Dwyer, P J, Geraghty, J G, O'Higgins, N J

“…To evaluate the effect of closing dead space on seroma formation after mastectomy, 39 patients undergoing 40 mastectomies with axillary node clearance were…”
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Vascular smooth muscle cells and neointimal hyperplasia in chronic transplant rejection by GERAGHTY, J. G, STOLTENBERG, R. L, SOLLINGER, H. W, HULLETT, D. A

“…Intimal hyperplasia is the characteristic pathological hallmark in the arterial tree of chronically rejecting solid organ grafts. Mechanisms underlying the…”
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CA 15-3 in patients with locoregional and metastatic breast carcinoma by Geraghty, J G, Coveney, E C, Sherry, F, O'Higgins, N J, Duffy, M J

“…The value of circulating CA 15-3 levels was assessed in 129 patients with recurrent breast carcinoma. Patients were divided into four subgroups, according to…”
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Follow up after primary treatment: curable diseases primarily treated with surgery by GERAGHTY, James G

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Reasons underlying negative mammography in patients with palpable breast cancer by Coveney, E C, Geraghty, J G, O'Laoide, R, Hourihane, J B, O'Higgins, N J

“…It is well recognized that a negative mammogram report does not exclude the presence of breast carcinoma. This study examines the accuracy of mammography in…”
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An elderly patient with advanced locoregional melanoma by Gennari, R., Stoldt, S.H., Testori, A., Geraghty, J.G.

“…There is no consensus on the management of cancer in elderly patients and age per se should not be the sole factor in the decision-making process. We present a…”
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Portal venous pressure and portasystemic shunting in experimental portal hypertension by Geraghty, J G, Angerson, W J, Carter, D C

“…The relationship between portal venous pressure and the degree of portasystemic shunting was studied in portal vein-ligated and cirrhotic rats anesthetized…”
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Psychosocial dimensions of BRCA testing: an overshadowed issue by Brédart, A., Autier, P., Riccardo, A., Audisio, A., Geraghty, J. G.

“…Routine cancer susceptibility testing will soon be feasible in clinical practice. However, to date, this new technology has entailed many limitations,…”
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