Search Results - "Georgopoulos, C"
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Computationally efficient seismic fragility analysis of geostructures
Published in Computers & structures (01-10-2009)“…Seismic fragility analysis is considered nowadays as a very efficient computational tool for determining the structural behaviour over a range of seismic…”
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2
A fuzzy cognitive map approach to differential diagnosis of specific language impairment
Published in Artificial intelligence in medicine (01-11-2003)“…This paper presents a computer-based model for differential diagnosis of specific language impairment (SLI), a language disorder that, in many cases, cannot be…”
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An international pilot study of asynchronous teleconsultation for oropharyngeal dysphagia
Published in Journal of telemedicine and telecare (01-02-2013)“…We investigated whether an expert's consultation provided via telemedicine could improve the quality of care for patients with dysphagia. A trained clinician…”
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4
Quality of Methods for Assessing and Reporting Serious Adverse Events in Clinical Trials of Cancer Drugs
Published in Clinical pharmacology and therapeutics (01-08-2010)“…The validity of information regarding drug toxicity in humans depends on the quality of the methods and instruments used to assess adverse drug events (ADEs)…”
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Polypeptide Flux through Bacterial Hsp70: DnaK Cooperates with Trigger Factor in Chaperoning Nascent Chains
Published in Cell (11-06-1999)“…A role for DnaK, the major E. coli Hsp70, in chaperoning de novo protein folding has remained elusive. Here we show that under nonstress conditions DnaK…”
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Reporting of serious adverse events during cancer clinical trials to the institutional review board: An evaluation by the Research on Adverse Drug events And Reports (RADAR) project
Published in Journal of clinical pharmacology (01-12-2013)“…Global introspection is considered an unreliable method for attribution of causality of serious adverse events (SAEs), yet remains widely used for cancer drug…”
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The NH2-terminal 108 amino acids of the Escherichia coli DnaJ protein stimulate the ATPase activity of DnaK and are sufficient for lambda replication
Published in The Journal of biological chemistry (18-02-1994)“…The Escherichia coli heat shock proteins DnaK and DnaJ function cooperatively as molecular chaperones. Central to their biochemical functions is the ability of…”
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8
Probabilistic seismic slope stability assessment of geostructures
Published in Structure and infrastructure engineering (01-02-2010)“…Typically, seismic analysis of large-scale geostructures, such as embankments, is performed by means of deterministic pseudostatic slope stability methods,…”
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Identification and characterization of HsIV HsIU (ClpQ ClpY) proteins involved in overall proteolysis of misfolded proteins in Escherichia coli
Published in The EMBO journal (16-12-1996)“…Heat shock response in Escherichia coli is autoregulated. Consistent with this, mutations in certain heat shock genes, such as dnaK, dnaJ, grpE or htrC lead to…”
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10
The groES and groEL heat shock gene products of Escherichia coli are essential for bacterial growth at all temperatures
Published in Journal of Bacteriology (01-03-1989)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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A novel mutation in the HSPD1 gene in a patient with hereditary spastic paraplegia
Published in Journal of neurology (01-07-2007)“…A mutation in the HSPD1 gene has previously been associated with an autosomal dominant form of spastic paraplegia in a French family. HSPD1 encodes heat shock…”
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12
Simulating the seismic response of embankments via artificial neural networks
Published in Advances in engineering software (1992) (01-08-2009)“…Geotechnical earthquake engineering may generally be considered as an “imprecise” scientific area due to the unavoidable uncertainties and the simplifications…”
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13
The Escherichia coli dsbC (xprA) gene encodes a periplasmic protein involved in disulfide bond formation
Published in The EMBO journal (15-04-1994)“…We have identified and functionally characterized a new Escherichia coli gene, dsbC, whose product is involved in disulfide bond formation in the periplasmic…”
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Isolation and characterization of ClpX, a new ATP-dependent specificity component of the Clp protease of Escherichia coli
Published in The Journal of biological chemistry (25-10-1993)“…We have used 14C-labeled bacteriophage lambda O-DNA replication protein as a probe to identify and purify Escherichia coli proteases capable of its…”
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15
Biological role and regulation of the universally conserved heat shock proteins
Published in The Journal of biological chemistry (25-12-1991)“…The heat shock (HS) or stress response has been conserved in evolution, from bacteria to man. Although the original discovery by Ritossa in Drosophila passed…”
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Escherichia coli DnaJ and GrpE Heat Shock Proteins Jointly Stimulate ATPase Activity of DnaK
Published in Proceedings of the National Academy of Sciences - PNAS (01-04-1991)“…The products of the Escherichia coli dnaK, dnaJ, and grpE heat shock genes have been previously shown to be essential for bacteriophage λ DNA replication at…”
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Identification and Characterization of the Escherichia coli Gene dsbB, Whose Product is Involved in the Formation of Disulfide Bonds in vivo
Published in Proceedings of the National Academy of Sciences - PNAS (01-08-1993)“…We have identified and characterized the Escherichia coli gene dsbB, whose product is required for disulfide bond formation of periplasmic proteins, by using…”
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The HtrA (DegP) protein, essential for Escherichia coli survival at high temperatures, is an endopeptidase
Published in Journal of Bacteriology (01-04-1990)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The Escherichia coli DnaK chaperone, the 70-kDa heat shock protein eukaryotic equivalent, changes conformation upon ATP hydrolysis, thus triggering its dissociation from a bound target protein
Published in The Journal of biological chemistry (05-08-1991)“…The DnaK protein of Escherichia coli and its eukaryotic hsp70 analogues are known to bind some polypeptides and to release or dissociate from them following…”
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The ClpX heat‐shock protein of Escherichia coli, the ATP‐dependent substrate specificity component of the ClpP‐ClpX protease, is a novel molecular chaperone
Published in The EMBO journal (01-05-1995)“…All major classes of protein chaperones, including DnaK (the Hsp70 eukaryotic equivalent) and GroEL (the Hsp60 eukaryotic equivalent) have been found in…”
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