Search Results - "Georgiou, Niki A."

Dual role of Toll-like receptors in asthma and chronic obstructive pulmonary disease by Bezemer, Gillina F G, Sagar, Seil, van Bergenhenegouwen, Jeroen, Georgiou, Niki A, Garssen, Johan, Kraneveld, Aletta D, Folkerts, Gert

“…During the last decade, significant research has been focused on Toll-like receptors (TLRs) in the pathogenesis of airway diseases. TLRs are pattern…”
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Bifidobacterium breve and Lactobacillus rhamnosus treatment is as effective as budesonide at reducing inflammation in a murine model for chronic asthma by Sagar, Seil, Morgan, Mary E, Chen, Si, Vos, Arjan P, Garssen, Johan, van Bergenhenegouwen, Jeroen, Boon, Louis, Georgiou, Niki A, Kraneveld, Aletta D, Folkerts, Gert

“…Asthma is estimated to affect as many as 300 million people worldwide and its incidence and prevalence are rapidly increasing throughout the world, especially…”
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Endothelial activation and induction of monocyte adhesion by nontransferrin‐bound iron present in human sera by Kartikasari, Apriliana E. R., Georgiou, Niki A., Visseren, Frank L. J., van Kats‐Renaud, Henny, Asbeck, B. Sweder, Marx, Joannes J. M.

“…ABSTRACT Nontransferrin‐bound iron (NTBI) has been detected in iron overload diseases. This form of iron may exert pro‐oxidant effects and modulate cellular…”
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Differential Regulation of Inflammation and Immunity in Mild and Severe Experimental Asthma by Verheijden, Kim A. T., Sagar, Seil, Georgiou, Niki A., Garssen, Johan, Kraneveld, Aletta D., Vos, Arjan P., Folkerts, Gert

“…This study aimed at exploring innate and adaptive immunity in allergic asthma by investigation of mRNA expression of pattern recognition receptors,…”
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Cigarette smoke induces β2-integrin-dependent neutrophil migration across human endothelium by Overbeek, Saskia A, Braber, Saskia, Henricks, Paul A J, Kleinjan, Marije, Kamp, Vera M, Georgiou, Niki A, Garssen, Johan, Kraneveld, Aletta D, Folkerts, Gert

“…Cigarette smoking induces peripheral inflammatory responses in all smokers and is the major risk factor for neutrophilic lung disease such as chronic…”
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Non-transferrin-bound iron and risk of coronary heart disease in postmenopausal women by VAN DER A, Daphne L, MARX, Joannes J. M, VAN DER SCHOUW, Yvonne T, GROBBEE, Diederick E, KAMPHUIS, Marjolein H, GEORGIOU, Niki A, VAN KATS-RENAUD, J. Henny, BREUER, William, IOAV CABANTCHIK, Z, ROEST, Mark, VOORBIJ, Hieronymus A. M

“…Epidemiological studies aimed at correlating coronary heart disease (CHD) with serum ferritin levels have thus far yielded inconsistent results. We…”
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Intracellular Labile Iron Modulates Adhesion of Human Monocytes to Human Endothelial Cells by Kartikasari, Apriliana E.R, Georgiou, Niki A, Visseren, Frank L.J, van Kats-Renaud, Henny, van Asbeck, B Sweder, Marx, Joannes J.M

“…OBJECTIVE—Elevated iron stores and high plasma iron concentration have been linked to an increased risk of atherosclerosis. Iron may thereby affect the…”
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Inhibition of Human Immunodeficiency Virus Type 1 Replication in Human Mononuclear Blood Cells by the Iron Chelators Deferoxamine, Deferiprone, and Bleomycin by Georgiou, Niki A., van der Bruggen, Tjomme, Oudshoorn, Maroeska, Nottet, Hans S. L. M., Marx, Joannes J. M., van Asbeck, B. Sweder

“…Replication of human immunodeficiency virus type 1 (HIV-1) can be influenced by iron. Hence, decreasing the availability of iron may inhibit HIV-1 replication…”
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Pharma–nutrition interface: The gap is narrowing by Georgiou, Niki A., Garssen, Johan, Witkamp, Renger F.

“…The interaction between pharmacology and nutrition science is on the rise. Nutritional status is considered one of the important determinants of health and…”
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The combination of Bifidobacterium breve with non-digestible oligosaccharides suppresses airway inflammation in a murine model for chronic asthma by Sagar, Seil, Vos, Arjan P., Morgan, Mary E., Garssen, Johan, Georgiou, Niki A., Boon, Louis, Kraneveld, Aletta D., Folkerts, Gert

“…Over the last decade, there has been a growing interest in the use of interventions that target the intestinal microbiota as a treatment approach for asthma…”
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Chemo-attractant N-acetyl proline–glycine–proline induces CD11b/CD18-dependent neutrophil adhesion by Overbeek, Saskia A., Kleinjan, Marije, Henricks, Paul A.J., Kamp, Vera M., Ricciardolo, Fabio L., Georgiou, Niki A., Garssen, Johan, Kraneveld, Aletta D., Folkerts, Gert

“…Chronic inflammation in lung diseases contributes to lung tissue destruction leading to the formation of chemotactic collagen fragments such as N-acetylated…”
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Impact of oral iron challenges on circulating non-transferrin-bound iron in healthy Guatemalan males by Schümann, Klaus, Kroll, Sylvia, Romero-Abal, Maria-Eugenia, Georgiou, Niki A, Marx, Jo J M, Weiss, Günter, Solomons, Noel W

“…Oral iron as a supplement has been associated with adverse health consequences, especially in the context of young children with active malaria. A potential…”
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Intracellular labile iron promotes firm adhesion of human monocytes to endothelium under flow and transendothelial migration Iron and monocyte-endothelial cell interactions by KARTIKASARI, Apriliana E. R, VISSEREN, Frank L. J, MARX, Joannes J. M, VAN MULLEKOM, Sanne, VAN KATS-RENAUD, J. Henny, VAN ASBECK, B. Sweder, ULFMAN, Laurien H, GEORGIOU, Niki A

“…Monocyte infiltration across the endothelium is part of the innate immune response, however it may contribute to severity of chronic conditions. We have…”
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Intracellular labile iron promotes firm adhesion of human monocytes to endothelium under flow and transendothelial migration by Kartikasari, Apriliana E.R, Visseren, Frank L.J, Marx, Joannes J.M, van Mullekom, Sanne, Kats-Renaud, J. Henny van, Asbeck, B. Sweder van, Ulfman, Laurien H, Georgiou, Niki A

“…Abstract Monocyte infiltration across the endothelium is part of the innate immune response, however it may contribute to severity of chronic conditions. We…”
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Can Iron Chelators Influence the Progression of Atherosclerosis? by Marx, Joannes J.M., Kartikasari, Apriliana E.R., Georgiou, Niki A.

“…Epidemiological studies and experimental data suggest iron involvement in atherosclerosis. The relation between iron and atherosclerosis is complex and remains…”
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Bleomycin has antiviral properties against drug-resistant HIV strains and sensitises virus to currently used antiviral agents by Georgiou, Niki A., van der Bruggen, Tjomme, Healy, Derek M.C., van Tienen, Carla, de Bie, Prim, Oudshoorn, Maroeska, Marx, Joannes J.M., van Asbeck, B. Sweder

“…In this study we performed phenotypic assays to assess involvement of the cancer chemotherapeutic agent bleomycin (BLM) in replication inhibition of mutant…”
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Mechanism of inhibition of the human immunodeficiency virus type 1 by the oxygen radical generating agent bleomycin by Georgiou, Niki A, van der Bruggen, Tjomme, Oudshoorn, Maroeska, de Bie, Prim, Jansen, Christine A, Nottet, Hans S.L.M, Marx, Joannes J.M, van Asbeck, B.Sweder

“…Alternative targets of attack of the human immunodeficiency virus (HIV) are necessary in light of infection persistence due to onset of resistance after…”
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The chemotherapeutic agent bleomycin in a two-drug combination with zidovudine, ritonavir or indinavir synergistically inhibits HIV Type-1 replication in peripheral blood lymphocytes by Georgiou, Niki A, van der Bruggen, Tjomme, Jansen, Christine A, Oudshoorn, Maroeska, Nottet, Hans S.L.M, Marx, Joannes J.M, van Asbeck, B.Sweder

“…It has been suggested that the combination of cancer chemotherapy with antiviral therapy is helpful for the containment of lymphomas in HIV-infected patients…”
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Combining iron chelators with the nucleoside analog didanosine in anti-HIV therapy by Georgiou, Niki A, van der Bruggen, Tjomme, Oudshoorn, Maroeska, Nottet, Hans H.L.M, Marx, Joannes J.M, Sweder van Asbeck, B

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The effect of deoxynucleosides on cell proliferation of peripheral blood lymphocytes treated with deferoxamine or hydroxyurea by Bruggen, Tjomme van der, Georgiou, Niki A, Oudshoorn, Maroeska, Nottet, Hans S.L.M, Marx, Joannes J.M, van Asbeck, B.Sweder

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