Search Results - "Georgiev, P. G"

Drosophila Protein Z4 Possesses ZAD Dimerization Domain by Bonchuk, A. N., Georgiev, P. G.

“…The transcription factor Z4 (putzig) is one of the key proteins that determine the chromatin structure in Drosophila . Z4 is found at the boundaries of bands…”
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C2H2 Zinc Finger Proteins: The Largest but Poorly Explored Family of Higher Eukaryotic Transcription Factors by Fedotova, A A, Bonchuk, A N, Mogila, V A, Georgiev, P G

“…The emergence of whole-genome assays has initiated numerous genome-wide studies of transcription factor localizations at genomic regulatory elements…”
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Impact of Interactions between Su(Hw)-Dependent Insulators on the Transvection Effect in Drosophila melanogaster by Melnikova, L. S., Molodina, V. V., Georgiev, P. G., Golovnin, A. K.

“…Transvection is a phenomenon of interallelic communication in which enhancers can activate a specific promoter located on a homologous chromosome. Insulators…”
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The NCoR Co-repressor Interacts with the Kaiso Transcription Factor through a Mechanism Different from That of BCL6 Interaction by Balagurov, K. I., Georgiev, P. G., Bonchuk, A. N.

“…The vertebrate transcription factor Kaiso binds specifically to methylated DNA sequences using C2H2-type zinc fingers. In addition to C2H2-domains, the BTB/POZ…”
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Study of the Association of Ouib and Nom with Heterochromatin in Drosophila melanogaster by Pekina, Y. V., Babosha, V. A., Georgiev, P. G., Fedotova, A. A.

“…In Drosophila , a large group of actively transcribed genes is located in pericentromeric heterochromatin. It is assumed that heterochromatic proteins recruit…”
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Study of the Role of Long Noncoding roX RNA in Maintaining of the Dosage Compensation Complex in Drosophila melanogaster by Babosha, V. A., Georgiev, P. G., Maksimenko, O. G.

“…The proteins MSL1, MSL2, MSL3, MLE, and MOF and noncoding RNAs roX1 and roX2 form the Drosophila dosage compensation complex (DCC), which specifically binds to…”
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Study of the in Vivo Functional Role of Mutations in the BTB Domain of the CP190 Protein of Drosophila melanogaster by Fedotova, A. A., Georgiev, P. G., Bonchuk, A. N.

“…The Drosophila transcription factor СР190 is one of the key proteins that determine the activity of housekeeping gene promoters and insulators. CP190 has an…”
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HspBP1 in Complex with the Peptide of the Innate Immunity Protein Tag7 is Able to Lyse Tumor Cells Carrying TNFR1 Receptor by Romanova, E. A., Yurkina, D. M., Yashin, D. V., Sashchenko, L. P., Georgiev, G. P.

“…The search for new cytotoxic agents capable of lysing tumor cells is an important task in the fight against cancer. Here we have shown that the HspBP1 protein,…”
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Selection of an Amino Acid Site with One of the Fastest Cleavage Kinetics by the Endosomal Protease Cathepsin B for Potential Use in Drug Delivery Systems by Khramtsov, Y. V., Georgiev, G. P., Sobolev, A. S.

“…On the basis of known published data, six peptide sequences were selected that are potentially capable of being rapidly cleaved by the endosomal protease…”
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Recruitment to Chromatin of (GA)n-Associated Factors GAF and Psq in the Transgenic Model System Depends on the Presence of Architectural Protein Binding Sites by Chetverina, D. A., Gorbenko, F. V., Lomaev, D. V., Georgiev, P. G., Erokhin, M. M.

“…Polycomb group (PcG) repressors and Trithorax group (TrxG) activators of transcription are essential for the proper development and maintenance of gene…”
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The Piragua Gene Is not Essential for Drosophila Development by Sokolov, V. V., Georgiev, P. G., Kyrchanova, O. V.

“…Proteins with clusters of C 2 H 2 zinc finger domains (C 2 H 2 -proteins) constitute the most abundant class of transcription factors in higher eukaryotes…”
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Study of the N-Terminal Domain Homodimerization in Human Proteins with Zinc Finger Clusters by Fursenko, D. V., Georgiev, P. G., Bonchuk, A. N.

“…CTCF belongs to a large family of transcription factors with clusters of C2H2-type zinc finger domains (C2H2 proteins) and is a main architectural protein in…”
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Modular Nanotransporters Capable of Binding to SARS-CoV-2 Virus Nucleocapsid Protein in Target Cells by Khramtsov, Y. V., Ulasov, A. V., Lupanova, T. N., Georgiev, G. P., Sobolev, A. S.

“…On the basis of literature data, an antibody-like molecule, monobody, was selected that is capable of interacting with the nucleocapsid protein (N protein) of…”
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Modular Nanotransporters Capable of Causing Intracellular Degradation of the N-Protein of the SARS-CoV-2 Virus in A549 Cells with Temporary Expression of This Protein Fused with a Fluorescent Protein mRuby3 by Khramtsov, Y. V., Ulasov, A. V., Lupanova, T. N., Georgiev, G. P., Sobolev, A. S.

“…Modular nanotransporters (MNTs) containing an antibody-like molecule, monobody, to the N‑protein of the SARS-CoV-2 virus, as well as an amino acid sequence…”
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Quantitative Description of the N-Protein of the SARS-CoV-2 Virus Degradation in Cells Stably Expressing It under the Influence of New Modular Nanotransporters by Khramtsov, Y. V., Ulasov, A. V., Lupanova, T. N., Georgiev, G. P., Sobolev, A. S.

“…Two eukaryotic cell lines, A549 and A431, with stable expression of the nucleocapsid protein (N-protein) of the SARS-CoV-2 virus fused with the red fluorescent…”
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Mutations of Phosphorylation Sites in MSL1 Protein Do Not Affect Dosage Compensation in Drosophila melanogaster by Babosha, V. A., Georgiev, P. G., Maksimenko, O. G.

“…Proteins MSL1 and MSL2 form the core of the Drosophila dosage compensation complex, which specifically binds to the X chromosome of males. Phosphorylation of…”
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Delivery of Antibody-Like Molecules, Monobodies, Capable of Binding with SARS-CoV-2 Virus Nucleocapsid Protein, into Target Cells by Khramtsov, Y. V., Ulasov, A. V., Lupanova, T. N., Georgiev, G. P., Sobolev, A. S.

“…Based on previous studies, two antibody-like molecules, monobodies, capable of high-affinity interaction with the SARS-CoV-2 nucleocapsid protein (dissociation…”
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TTK Isoforms Interact with Two Regions of the Mep-1 Protein of Drosophila melanogaster by Khalisova, K. Y., Osadchiy, I. S., Georgiev, P. G., Maksimenko, O. G.

“…The Drosophila TTK protein is involved in the processes of cell differentiation and is represented by two isoforms, TTK69 and TTK88, which have a common…”
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Human CTCF Interacts with Drosophila CP190, but not with Kaiso by Khalisova, K. Y., Georgiev, P. G., Bonchuk, A. N.

“…Human CTCF (hCTCF) is a major architectural protein in mammals. In Drosophila, the CTCF homologue (dCTCF) interacts with the BTB domain of the CP190 protein,…”
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Intracellular Delivery of an Antibody-Like Molecule Capable of Inhibiting c-Myc by Lupanova, T. N., Ulasov, A. V., Khramtsov, Y. V., Rozenkranz, A. A., Georgiev, G. P., Sobolev, A. S.

“…A modular nanotransporter (MNT) carrying the sequence of an antibody-like molecule, anti-c-Myc nanobody, was synthesized and characterized. It was demonstrated…”
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