Search Results - "Georgiev, Kaloyan D."
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Isolation, analysis and in vitro assessment of CYP3A4 inhibition by methylxanthines extracted from Pu-erh and Bancha tea leaves
Published in Scientific reports (26-09-2019)“…Methylxanthines, purine alkaloids found in plants, are found in beverages (coffee, tea, cocoa) and foods (chocolate and other cocoa-containing foods) commonly…”
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The role of the clinical pharmacist in the prevention of potential drug interactions in geriatric heart failure patients
Published in International journal of clinical pharmacy (01-12-2019)“…Background The treatment of heart failure patients is very complex and includes lifestyle modification as well as different pharmacological therapies…”
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INNs granted with specific storage requirements in Bulgarian pharmacies. Part 2: Antineoplastic and immunomodulating agents
Published in Farmacija (20-09-2023)“…There are drugs that require special storage in Bulgarian pharmacies as well as extra caution during the dispensing process. This is due to serious adverse…”
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INNs granted with specific storage requirements in Bulgarian pharmacies. Part 1: Medicines acting on cardiovascular and nervous system
Published in Farmacija (25-08-2023)“…Some medicines require special storage in Bulgarian pharmacies due to serious adverse reactions that may be even life-threatening. They are listed in Appendix…”
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Cardio- and nephroprotective effects of fractions isolated from Lycium barbarum (goji berry) in models of cardio- and nephrotoxicity in rats
Published in Biotechnology, biotechnological equipment (31-12-2023)“…The aim of the present study was to identify agents that reduce the anthracyclines-induced cardiovascular and renal damage and have the potential to enhance…”
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In vitro antiviral activities of fruit extract from Lycium barbarum and methylxanthines extracted from Pu-erh and Bancha tea leaves
Published in Folia Medica (31-10-2022)“…Introduction : Based on traditional medicine, many countries use various plant products (fruits, leaves and other plant parts) as food supplements or in the…”
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Erucylphospho-N,N,N-trimethylpropylammonium (erufosine) is a potential antimyeloma drug devoid of myelotoxicity
Published in Cancer chemotherapy and pharmacology (01-01-2011)“…Purpose Erufosine is an i.v. injectable alkylphosphocholine which is active against various haematological malignancies in vitro. In the present study, its…”
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Prevalence of polypharmacy and risk of potential drug-drug interactions among hospitalized patients with emphasis on the pharmacokinetics
Published in Science progress (1916) (01-01-2022)“…Background: Both polypharmacy and potential drug-drug interactions (pDDIs), especially those at the pharmacokinetic level, are common in hospitalized patients…”
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Influence of methylxanthines isolated from Bancha green tea on the pharmacokinetics of sildenafil in rats
Published in Daru (01-06-2022)“…Background Sildenafil is used to treat erectile dysfunction and pulmonary arterial hypertension and is metabolized in the liver mainly by CYP3A4, thus…”
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Antioxidant Activity and Antiproliferative Effects of Lycium barbarum’s (Goji berry) Fractions on Breast Cancer Cell Lines
Published in Folia Medica (01-03-2019)“…Background: Lycium barbarum has gained immense popularity over the past decade because of its antioxidant properties. There are many reports of observed health…”
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Protective Effect of Methylxanthine Fractions Isolated from Bancha Tea Leaves against Doxorubicin-Induced Cardio- and Nephrotoxicities in Rats
Published in BioMed research international (2020)“…Doxorubicin is an anthracycline antibiotic that is used for the treatment of various types of cancer. However, its clinical usage is limited due to its…”
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RIPK3 expression as a potential predictive and prognostic marker in metastatic colon cancer
Published in Clinical and investigative medicine (23-03-2019)“…Colorectal cancer is one of the primary causes of cancer-related deaths and 5-fluorouracil (5-FU) therapy remains the cornerstone of treatment in these…”
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NEW PHARMACOLOGICAL APPROACHES IN THE TREATMENT OF ONCOLOGICAL DISEASES
Published in Journal of IMAB (01-07-2015)“…Malignant diseases are significant and growing health problem in almost all countries of the world. Besides the results achieved in reduction of morbidity and…”
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In vitro antiviral activities of fruit extract from Lycium barbarum and methylxanthines extracted from Pu-erh and Bancha tea leaves
Published in Folia medica (31-10-2022)“…Based on traditional medicine, many countries use various plant products (fruits, leaves and other plant parts) as food supplements or in the form of tea. The…”
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15
Antioxidant Activity and Antiproliferative Effects of Lycium barbarum's (Goji berry) Fractions on Breast Cancer Cell Lines
Published in Folia medica (01-03-2019)“…Lycium barbarum has gained immense popularity over the past decade because of its antioxidant properties. There are many reports of observed health benefits of…”
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Journal Article