Search Results - "Georgiev, Hristo"

Recent advances in iNKT cell development [version 1; peer review: awaiting peer review] by Hogquist, Kristin, Georgiev, Hristo

“…Recent studies suggest that murine invariant natural killer T (iNKT) cell development culminates in three terminally differentiated iNKT cell subsets denoted…”
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Coming of Age: CD96 Emerges as Modulator of Immune Responses by Georgiev, Hristo, Ravens, Inga, Papadogianni, Georgia, Bernhardt, Günter

“…CD96 represents a type I transmembrane glycoprotein belonging to the immunoglobulin superfamily. CD96 is expressed mainly by cells of hematopoietic origin, in…”
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Classical MHC expression by DP thymocytes impairs the selection of non-classical MHC restricted innate-like T cells by Georgiev, Hristo, Peng, Changwei, Huggins, Matthew A., Jameson, Stephen C., Hogquist, Kristin A.

“…Conventional T cells are selected by peptide-MHC expressed by cortical epithelial cells in the thymus, and not by cortical thymocytes themselves that do not…”
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Distinct gene expression patterns correlate with developmental and functional traits of iNKT subsets by Georgiev, Hristo, Ravens, Inga, Benarafa, Charaf, Förster, Reinhold, Bernhardt, Günter

“…Invariant natural killer T (iNKT) cells comprise a subpopulation of innate lymphocytes developing in thymus. A new model proposes subdividing murine iNKT cells…”
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Techniques and challenges in the assimilation of atmospheric water observations for numerical weather prediction towards convective scales by Bannister, Ross Noel, Chipilski, Hristo Georgiev, Martinez‐Alvarado, Oscar

“…While contemporary numerical weather prediction models represent the large‐scale structure of moist atmospheric processes reasonably well, they often struggle…”
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Epigenetic silencing of ZIC4 unveils a potential tumor suppressor role in pediatric choroid plexus carcinoma by Hesham, Dina, Mosaab, Amal, Amer, Nada, Al-Shehaby, Nouran, Magdeldin, Sameh, Hassan, Ahmed, Georgiev, Hristo, Elshoky, Hisham, Rady, Mona, Aisha, Khaled Abou, Sabet, Ola, El-Naggar, Shahenda

“…Zic family member ZIC4 is a transcription factor that has been shown to be silenced in several cancers. However, understanding the regulation and function of…”
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Impact of Aging on the Phenotype of Invariant Natural Killer T Cells in Mouse Thymus by Papadogianni, Georgia, Ravens, Inga, Dittrich-Breiholz, Oliver, Bernhardt, Günter, Georgiev, Hristo

“…Invariant natural killer T (iNKT) cells represent a subclass of T cells possessing a restricted repertoire of T cell receptors enabling them to recognize lipid…”
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Intrinsic factors and CD1d1 but not CD1d2 expression levels control invariant natural killer T cell subset differentiation by Amable, Ludivine, Ferreira Martins, Luis Antonio, Pierre, Remi, Do Cruseiro, Marcio, Chabab, Ghita, Sergé, Arnauld, Kergaravat, Camille, Delord, Marc, Viret, Christophe, Jaubert, Jean, Liu, Chaohong, Karray, Saoussen, Marie, Julien C., Irla, Magali, Georgiev, Hristo, Clave, Emmanuel, Toubert, Antoine, Lucas, Bruno, Klibi, Jihene, Benlagha, Kamel

“…Invariant natural killer T (NKT) cell subsets are defined based on their cytokine-production profiles and transcription factors. Their distribution is…”
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Efficient IL-2R signaling differentially affects the stability, function, and composition of the regulatory T-cell pool by Permanyer, Marc, Bošnjak, Berislav, Glage, Silke, Friedrichsen, Michaela, Floess, Stefan, Huehn, Jochen, Patzer, Gwendolyn E., Odak, Ivan, Eckert, Nadine, Zargari, Razieh, Ospina-Quintero, Laura, Georgiev, Hristo, Förster, Reinhold

“…Signaling via interleukin-2 receptor (IL-2R) is a requisite for regulatory T (Treg) cell identity and function. However, it is not completely understood to…”
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RORγt+ c-Maf+ Vγ4+ γδ T cells are generated in the adult thymus but do not reach the periphery by Yang, Tao, Barros-Martins, Joana, Wang, Ziqing, Wencker, Melanie, Zhang, Jiang, Smout, Justine, Gambhir, Prerna, Janssen, Anika, Schimrock, Anja, Georgiev, Hristo, León-Lara, Ximena, Weiss, Siegfried, Huehn, Jochen, Prinz, Immo, Krueger, Andreas, Foerster, Reinhold, Walzer, Thierry, Ravens, Sarina

“…T cell receptor (TCR) Vγ4-expressing γδ T cells comprise interferon γ (IFNγ)- and interleukin-17 (IL-17)-producing effector subsets, with a preference for…”
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MCK2-mediated MCMV infection of macrophages and virus dissemination to the salivary gland depends on MHC class I molecules by Bošnjak, Berislav, Henze, Elisa, Lueder, Yvonne, Do, Kim Thi Hoang, Rezalotfi, Alaleh, Čuvalo, Berislav, Ritter, Christiane, Schimrock, Anja, Willenzon, Stefanie, Georgiev, Hristo, Fritz, Lea, Galla, Melanie, Wagner, Karen, Messerle, Martin, Förster, Reinhold

“…Murine cytomegalovirus (MCMV) infection of macrophages relies on MCMV-encoded chemokine 2 (MCK2), while infection of fibroblasts occurs independently of MCK2…”
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CD155/CD226‐interaction impacts on the generation of innate CD8+ thymocytes by regulating iNKT‐cell differentiation by Georgiev, Hristo, Ravens, Inga, Shibuya, Akira, Förster, Reinhold, Bernhardt, Günter

“…The cell surface receptor CD155 influences a variety of immune processes by binding to its ligands CD226, CD96, or TIGIT. Here, we report that the interaction…”
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Shared and Unique Features Distinguishing Follicular T Helper and Regulatory Cells of Peripheral Lymph Node and Peyer's Patches by Georgiev, Hristo, Ravens, Inga, Papadogianni, Georgia, Halle, Stephan, Malissen, Bernard, Loots, Gabriela G, Förster, Reinhold, Bernhardt, Günter

“…Follicular helper (TFH) and regulatory (TFR) cells are critical players in managing germinal center (GC) reactions that accomplish effective humoral immune…”
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Anti-Idiotype scFv Localizes an Autoepitope in the Globular Domain of C1q by Todorova, Nadezhda, Rangelov, Miroslav, Bogoeva, Vanya, Stoyanova, Vishnya, Yordanova, Anna, Nikolova, Ginka, Georgiev, Hristo, Dimitrova, Daniela, Mohedin, Safa, Stoyanova, Katerina, Tsacheva, Ivanka

“…We addressed the issue of C1q autoantigenicity by studying the structural features of the autoepitopes recognized by the polyclonal anti-C1q antibodies present…”
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The impact of stress on the transcriptomic signature of iNKT1 cells by Papadogianni, Georgia, Ravens, Inga, Hassan, Ahmed, Dittrich-Breiholz, Oliver, Bernhardt, Günter, Georgiev, Hristo

“…Invariant natural killer T (iNKT) cells develop in thymus before emigrating and settling peripheral tissues and organs. In contrast to regular naïve T cells,…”
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Establishment and Functional Characterization of Murine Monoclonal Antibodies Recognizing Neuritin by Papadogianni, Georgia, Ravens, Inga, Hassan, Ahmed, Flatley, Andrew, Feederle, Regina, Bernhardt, Günter, Georgiev, Hristo

“…Neuritin represents a neurotrophic factor that is not only important in neuronal development and plasticity but also impacts endothelial angiogenesis, cell…”
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Overexpression of Vα14Jα18 TCR promotes development of iNKT cells in the absence of miR‐181a/b‐1 by Blume, Jonas, Lage, Susanne, Witzlau, Katrin, Georgiev, Hristo, Weiss, Siegfried, Łyszkiewicz, Marcin, Ziȩtara, Natalia, Krueger, Andreas

“…Expression of microRNA miR‐181a/b‐1 is critical for intrathymic development of invariant natural killer T (iNKT) cells. However, the underlying mechanism has…”
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Carbonate apatite formation on novel multiphase CaO-SiO2-P2O5-MgO glass-ceramics in TRIS-HCl buffer by Lachezar Radev, Irena Michailova, Hristo Georgiev, Diana Zaimova

“…The main purpose of the presented article is the preparation of novel glass-ceramics in CaO-SiO2-P2O5-MgO system and evaluation of carbonate apatite formation…”
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To the EditorTIGIT versus CD226: Hegemony or coexistence? by Georgiev, Hristo, Danisch, Simon, Chambers, Benedict J., Shibuya, Akira, Förster, Reinhold, Bernhardt, Günter

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In vitro bioactivity of glass-ceramic/fibroin composites by Lachezar Radev, Irena Michailova, Silviya Stateva, Diana Zaimova, Hristo Georgiev, Margarita Apostolova

“…Bioactive composite materials were prepared by mixing 20 wt.% of silk fibroin (SF) and 80 wt.% of glassceramics from CaO-SiO2-P2O5-MgO system. In vitro…”
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