Search Results - "Georgieff, M.K."

Temporal manipulation of transferrin-receptor-1-dependent iron uptake identifies a sensitive period in mouse hippocampal neurodevelopment by Fretham, S.J.B., Carlson, E.S., Wobken, J., Tran, P.V., Petryk, A., Georgieff, M.K.

“…Iron is a necessary substrate for neuronal function throughout the lifespan, but particularly during development. Early life iron deficiency (ID) in humans…”
Get full text

Identification and Localization of Divalent Metal Transporter-1 (DMT-1) in Term Human Placenta by Georgieff, M.K., Wobken, J.K., Welle, J., Burdo, J.R., Connor, J.R.

“…The mechanism by which iron is transported from mother to fetus is incompletely understood. Whereas transferrin receptor (TfR) is responsible for iron uptake…”
Get full text

Pre-pregnancy weight, rate of gestational weight gain and risk of infant leukemia by Blair, C.K, Linabery, A.M, Eberly, L.E, Georgieff, M.K, Ross, J.A

Get full text

Increased N-glycosylation and reduced transferrin-binding capacity of transferrin receptor isolated from placentae of diabetic women by Georgieff, M.K., Petry, C.D., Mills, M.M., McKay, H., Wobken, J.D.

“…Infants of diabetic mothers are frequently born iron deficient because their fetal iron demand exceeds placental iron transport capacity. Although transferrin…”
Get full text

Eltrombopag, a thrombopoietin mimetic, crosses the blood–brain barrier and impairs iron‐dependent hippocampal neuron dendrite development by Bastian, T. W., Duck, K. A., Michalopoulos, G. C., Chen, M. J., Liu, Z.‐J., Connor, J. R., Lanier, L. M., Sola‐Visner, M. C., Georgieff, M. K.

“…Essentials Potential neurodevelopmental side effects of thrombopoietin mimetics need to be considered. The effects of eltrombopag (ELT) on neuronal iron status…”
Get full text

Perinatal brain iron deficiency increases the vulnerability of rat hippocampus to hypoxic ischemic insult by Rao, R, de Ungria, M, Sullivan, D, Wu, P, Wobken, J D, Nelson, C A, Georgieff, M K

“…Fetal brain iron deficiency occurs in human pregnancies complicated by diabetes mellitus or intrauterine growth retardation. Because neurocognitive deficits…”
Get more information

Gestational and Postnatal Iron Deficiency Alters the Developing Striatal Neurochemical Profile and Behaviors in the Young Rat by Ward, K.L., Tkac, I., Felt, B., Lozoff, B., Georgieff, M.K., Rao, R.

Get full text

Increased Placental Iron Regulatory Protein-1 Expression in Diabetic Pregnancies Complicated by Fetal Iron Deficiency by Georgieff, M.K., Berry, S.A., Wobken, J.D., Leibold, E.A.

“…Placental transferrin receptor (TfR) protein expression is increased in diabetic pregnancies that are complicated by low fetal iron stores, suggesting…”
Get full text

Aluminum toxicity in infants and children by Klish, W.I, Baker, S.S, Flores, C.A, Georgieff, M.K, Lake, A.M, Leibel, R.L, Udall, J.N

“…Dialysis encephalopathy and fracturing osteomalacia, which occur in hemodialysis units that use dialysis fluid contaminated with aluminum, have largely…”
Get full text

Fluoride supplementation for children: interim policy recommendations by Klish, W.J, Baker, S.S, Flores, C.A, Georgieff, M.K, Lake, A.M, Leibel, R.L, Udall, J.N

“…The Committee on Nutrition of the American Academy of Pediatrics (AAP) last issued a statement in 1986 on the topic of fluoride supplementation for children…”
Get full text

Placental transferrin receptor in diabetic pregnancies with increased fetal iron demand by Petry, C.D. (University of Minnesota School of Medicine, Minneapolis, MN.), Wobken, J.D, McKay, H, Eaton, M.A, Seybold, V.S, Johnson, D.E, Georgieff, M.K

“…Augmented fetal hemoglobin synthesis during diabetic pregnancy increases fetal iron demand. To study the effect of increased fetal iron demand on placental…”
Get full text

Use of high-fat formula for premature infants with bronchopulmonary dysplasia: Metabolic, pulmonary, and nutritional studies by Pereira, Gilberto R., Baumgart, Stephen, Bennett, Michael J., Stallings, Virginia A., Georgieff, Michael K., Hamosh, Margit, Ellis, Lorie

“…The use of dietary fat in preference to carbohydrate offers the theoretic advantage of diminishing carbon dioxide production and thus the respiratory quotient,…”
Get full text

Mid-arm circumference and mid-arm/head circumference ratios: standard curves for anthropometric assessment of neonatal nutritional status by Sasanow, S R, Georgieff, M K, Pereira, G R

“…Two hundred four neonates, 25 to 42 weeks estimated gestational age (EGA), were measured on day 2 or 3 of life for upper mid-arm circumference (MAC) and head…”
Get more information

Intravenous iron supplementation effect on tissue iron and hemoproteins in chronically phelbotomized lambs by Guiang, S.F. III, Georgieff, M.K, Lambert, d.J, Schmidt, R.L, Widness, J.A

Get full text

Effect of neonatal caloric deprivation on head growth and 1-year developmental status in preterm infants by Georgieff, M K, Hoffman, J S, Pereira, G R, Bernbaum, J, Hoffman-Williamson, M

“…The effects of neonatal illness and caloric intake on head growth velocity and on 1-year developmental outcome were studied in 73 appropriate (AGA) and small…”
Get more information

Effect of postnatal steroid administration on serum vitamin A concentrations in newborn infants with respiratory compromise by Georgieff, M K, Mammel, M C, Mills, M M, Gunter, E W, Johnson, D E, Thompson, T R

Get more information

Catch-up growth, muscle and fat accretion, and body proportionality of infants one year after newborn intensive care by Georgieff, M K, Mills, M M, Zempel, C E, Chang, P N

“…We studied catch-up growth, muscle and fat accretion, and body proportionality at 4 and 12 months of age corrected for prematurity in 30 very low birth weight…”
Get more information

influence of gestational age, size for dates, and prenatal steroids on cord transferrin levels in newborn infants by Chockalingam, U, Murphy, E, Ophoven, J.C, Georgieff, M.K

“…Extract: Serum transferrin levels assess protein status in older children and adults. To generate standards for its use in newborn infants, we measured…”
Get full text