Search Results - "Georgiadou, Athina"

Immunopathology of Acute Kidney Injury in Severe Malaria by Katsoulis, Orestis, Georgiadou, Athina, Cunnington, Aubrey J

“…Acute kidney injury (AKI) is a common feature of severe malaria, and an independent risk factor for death. Previous research has suggested that an…”
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Comparative transcriptomic analysis reveals translationally relevant processes in mouse models of malaria by Georgiadou, Athina, Dunican, Claire, Soro-Barrio, Pablo, Lee, Hyun Jae, Kaforou, Myrsini, Cunnington, Aubrey J

“…Recent initiatives to improve translation of findings from animal models to human disease have focussed on reproducibility but quantifying the relevance of…”
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Localised release of matrix metallopeptidase 8 in fatal cerebral malaria by Georgiadou, Athina, Naidu, Praveena, Walsh, Sophie, Kamiza, Steve, Barrera, Valentina, Harding, Simon P, Moxon, Christopher A, Cunnington, Aubrey J

“…Objective Cerebral malaria (CM) is a complication of Plasmodium falciparum malaria, in which progressive brain swelling is associated with sequestration of…”
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Shedding of the Vascular Endothelial Glycocalyx: A Common Pathway to Severe Malaria? by Georgiadou, Athina, Cunnington, Aubrey J

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Integrated pathogen load and dual transcriptome analysis of systemic host-pathogen interactions in severe malaria by Lee, Hyun Jae, Georgiadou, Athina, Walther, Michael, Nwakanma, Davis, Stewart, Lindsay B, Levin, Michael, Otto, Thomas D, Conway, David J, Coin, Lachlan J, Cunnington, Aubrey J

“…The pathogenesis of infectious diseases depends on the interaction of host and pathogen. In malaria, host and parasite processes can be assessed by dual RNA…”
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Transcriptomic Studies of Malaria: a Paradigm for Investigation of Systemic Host-Pathogen Interactions by Lee, Hyun Jae, Georgiadou, Athina, Otto, Thomas D, Levin, Michael, Coin, Lachlan J, Conway, David J, Cunnington, Aubrey J

“…Transcriptomics, the analysis of genome-wide RNA expression, is a common approach to investigate host and pathogen processes in infectious diseases. Technical…”
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Neutrophil extracellular traps drive inflammatory pathogenesis in malaria by Knackstedt, Sebastian Lorenz, Georgiadou, Athina, Apel, Falko, Abu-Abed, Ulrike, Moxon, Christopher A, Cunnington, Aubrey J, Raupach, Bärbel, Cunningham, Deirdre, Langhorne, Jean, Krüger, Renate, Barrera, Valentina, Harding, Simon P, Berg, Aase, Patel, Sam, Otterdal, Kari, Mordmüller, Benjamin, Schwarzer, Evelin, Brinkmann, Volker, Zychlinsky, Arturo, Amulic, Borko

“…Neutrophils are essential innate immune cells that extrude chromatin in the form of neutrophil extracellular traps (NETs) when they die. This form of cell…”
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S100P enhances the motility and invasion of human trophoblast cell lines by Tabrizi, Maral E. A., Lancaster, Tara L., Ismail, Thamir M., Georgiadou, Athina, Ganguly, Ankana, Mistry, Jayna J., Wang, Keqing, Rudland, Philip S., Ahmad, Shakil, Gross, Stephane R.

“…S100P has been shown to be a marker for carcinogenesis where its expression in solid tumours correlates with metastasis and a poor patient prognosis. This…”
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Modelling pathogen load dynamics to elucidate mechanistic determinants of host–Plasmodium falciparum interactions by Georgiadou, Athina, Lee, Hyun Jae, Walther, Michael, van Beek, Anna E., Fitriani, Fadlila, Wouters, Diana, Kuijpers, Taco W., Nwakanma, Davis, D’Alessandro, Umberto, Riley, Eleanor M., Otto, Thomas D., Ghani, Azra, Levin, Michael, Coin, Lachlan J., Conway, David J., Bretscher, Michael T., Cunnington, Aubrey J.

“…During infection, increasing pathogen load stimulates both protective and harmful aspects of the host response. The dynamics of this interaction are hard to…”
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Potent Virustatic Polymer–Lipid Nanomimics Block Viral Entry and Inhibit Malaria Parasites In Vivo by Najer, Adrian, Blight, Joshua, Ducker, Catherine B., Gasbarri, Matteo, Brown, Jonathan C., Che, Junyi, Høgset, Håkon, Saunders, Catherine, Ojansivu, Miina, Lu, Zixuan, Lin, Yiyang, Yeow, Jonathan, Rifaie-Graham, Omar, Potter, Michael, Tonkin, Renée, Penders, Jelle, Doutch, James J., Georgiadou, Athina, Barriga, Hanna M. G., Holme, Margaret N., Cunnington, Aubrey J., Bugeon, Laurence, Dallman, Margaret J., Barclay, Wendy S., Stellacci, Francesco, Baum, Jake, Stevens, Molly M.

“…Infectious diseases continue to pose a substantial burden on global populations, requiring innovative broad-spectrum prophylactic and treatment alternatives…”
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