Search Results - "Georges Haddad"
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Modified mRNAs in the Cardiovascular System: A New Platform for Gene Therapy
Published in Molecular therapy (07-06-2017)“…[...]like all viral vectors, AAVs can only be administered once because they elicit neutralizing antibodies that preclude re-injection. [...]recently,…”
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2
An Intersubunit Interaction between S4-S5 Linker and S6 Is Responsible for the Slow Off-gating Component in Shaker K+ Channels
Published in The Journal of biological chemistry (30-04-2010)“…Voltage-gated ion channels are controlled by the membrane potential, which is sensed by peripheral, positively charged voltage sensors. The movement of the…”
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3
Mode shift of the voltage sensors in Shaker K+ channels is caused by energetic coupling to the pore domain
Published in The Journal of general physiology (01-05-2011)“…The voltage sensors of voltage-gated ion channels undergo a conformational change upon depolarization of the membrane that leads to pore opening. This…”
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Expressive suppression moderates the relationship between PTSD from COVID-19 and somatization and validation of the Arabic version of Patient Health Questionnaire-15 (PHQ-15)
Published in PloS one (25-01-2024)“…Lebanese adults have been crippled for years by several crises, including the lately COVID-19 pandemic. These massive civilian traumas have increased the risk…”
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5
Alcoholism: A Multi-Systemic Cellular Insult to Organs
Published in International journal of environmental research and public health (28-05-2018)“…Alcohol abuse can affect more than the heart and the liver. Many observers often do not appreciate the complex and differing aspects of alcohol's effects in…”
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A Common Kinetic Property of Mutations Linked to Episodic Ataxia Type 1 Studied in the Shaker Kv Channel
Published in International journal of molecular sciences (14-10-2020)“…(1) Background: Episodic ataxia type 1 is caused by mutations in the gene encoding for the voltage-gated potassium channel Kv1.1. There have been many…”
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The moderating effect of cognitive impairment on the relationship between inner speech and auditory verbal hallucinations among chronic patients with schizophrenia
Published in BMC psychiatry (14-06-2023)“…Even though there is an increasing amount of evidence from behavioral and neuroimaging studies to suggest that pathological inner speech plays a role in the…”
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Alcohol-Mediated Organ Damages: Heart and Brain
Published in Frontiers in pharmacology (13-02-2018)“…Alcohol is one of the most commonly abused substances in the United States. Chronic consumption of ethanol has been responsible for numerous chronic diseases…”
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Decreased insight, but not self-stigma or belief about medicine, is associated with greater severity of delusions in a sample of long-stay patients with schizophrenia: a cross-sectional study
Published in BMC psychiatry (03-04-2023)“…There are, to date, limited and inconsistent findings concerning the relationship between insight and psychotic symptoms, despite some evidence in favor of the…”
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Heavy Metals Accumulation Effects on The Photosynthetic Performance of Geophytes in Mediterranean Reserve
Published in Journal of King Saud University. Science (01-01-2020)“…In Bentael natural reserve, Byblos-Lebanon, a recently constructed road, adjacent to its Southside, is threatening the wildlife of the reserve. The first…”
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Could “cellular exercise” be the missing ingredient in a healthy life? Diets, caloric restriction, and exercise-induced hormesis
Published in Nutrition (Burbank, Los Angeles County, Calif.) (01-07-2022)“…•Poor dietary choices and physical inactivity are the leading causes of death from stroke, heart disease, and cancer worldwide.•Chronic overnutrition triggers…”
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Direct and indirect cardiovascular and cardiometabolic sequelae of the combined anti-retroviral therapy on people living with HIV
Published in Frontiers in physiology (27-03-2023)“…With reports of its emergence as far back as the early 1900s, human immunodeficiency virus (HIV) has become one of the deadliest and most difficult viruses to…”
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A cross-sectional study of current and lifetime sexual hallucinations and delusions in Lebanese patients with schizophrenia: frequency, characterization, and association with childhood traumatic experiences and disease severity
Published in BMC psychiatry (27-05-2022)“…Till that date, a sparse body of research has been dedicated to perusing psychotic symptoms of sexual type, particularly in psychiatric populations. Our…”
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Sequelae and Comorbidities of COVID-19 Manifestations on the Cardiac and the Vascular Systems
Published in Frontiers in physiology (14-01-2022)“…COVID-19 patients with pre-existing cardiovascular conditions are at greater risk of severe illness due to the SARS-CoV-2 (severe acute respiratory syndrome…”
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CXCR4 Cardiac Specific Knockout Mice Develop a Progressive Cardiomyopathy
Published in International journal of molecular sciences (08-05-2019)“…Activation of multiple pathways is associated with cardiac hypertrophy and heart failure. We previously published that CXCR4 negatively regulates β-adrenergic…”
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The role of coronary microvascular disorder in congestive heart failure
Published in American journal of physiology. Heart and circulatory physiology (15-04-2015)Get more information
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Functionality appreciation is inversely associated with positive psychotic symptoms in overweight/obese patients with schizophrenia
Published in BMC psychiatry (01-05-2023)“…While the relationship between negative aspects of body image and positive schizophrenia symptoms was extensively investigated and is relatively…”
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Regarding “A systematic review and meta-analysis of one-stage versus two-stage brachiobasilic arteriovenous fistula creation”
Published in Journal of vascular surgery (01-11-2018)Get full text
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Cross-cultural adaptation and validation of the Arabic version of the BACS scale (the brief assessment of cognition in schizophrenia) among chronic schizophrenic inpatients
Published in BMC psychiatry (01-05-2021)“…Assessment of cognitive disorders in schizophrenia is becoming a part of clinical and research practice by using batteries that differ widely in their content…”
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Adenoid Cystic Carcinoma of the Lacrimal Gland
Published in Iranian journal of ophthalmology (01-01-2024)“…Abstract Purpose: To explore the various aspects of adenoid cystic carcinoma of the lacrimal gland (LACC), including its clinical features, presentations,…”
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