Search Results - "Georges, Arthur"
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dartr: An r package to facilitate analysis of SNP data generated from reduced representation genome sequencing
Published in Molecular ecology resources (01-05-2018)“…Although vast technological advances have been made and genetic software packages are growing in number, it is not a trivial task to analyse SNP data. We…”
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Microchromosomes are building blocks of bird, reptile, and mammal chromosomes
Published in Proceedings of the National Academy of Sciences - PNAS (09-11-2021)“…Microchromosomes, once considered unimportant shreds of the chicken genome, are gene-rich elements with a high GC content and few transposable elements. Their…”
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Developmental dynamics of sex reprogramming by high incubation temperatures in a dragon lizard
Published in BMC genomics (22-04-2022)“…In some vertebrate species, gene-environment interactions can determine sex, driving bipotential gonads to differentiate into either ovaries or testes. In the…”
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Two transcriptionally distinct pathways drive female development in a reptile with both genetic and temperature dependent sex determination
Published in PLoS genetics (15-04-2021)“…How temperature determines sex remains unknown. A recent hypothesis proposes that conserved cellular mechanisms (calcium and redox; 'CaRe' status) sense…”
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Identification of Y chromosome markers in the eastern three-lined skink (Bassiana duperreyi) using in silico whole genome subtraction
Published in BMC genomics (29-09-2020)“…Homologous sex chromosomes can differentiate over time because recombination is suppressed in the region of the sex determining locus, leading to the…”
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Waking the sleeping dragon: gene expression profiling reveals adaptive strategies of the hibernating reptile Pogona vitticeps
Published in BMC genomics (06-06-2019)“…Hibernation is a physiological state exploited by many animals exposed to prolonged adverse environmental conditions associated with winter. Large changes in…”
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Dispersal and climate warming determine range shift in model reptile populations
Published in Ecological modelling (24-05-2016)“…•Reptiles with biased sex-ratios can expand their ranges as climates warm.•Even sex ratios do not set the limits of range expansion.•A simulation model was…”
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Climate warming drives a temperate-zone lizard to its upper thermal limits, restricting activity, and increasing energetic costs
Published in Scientific reports (13-06-2023)“…Lizards are considered vulnerable to climate change because many operate near their thermal maxima. Exposure to higher temperatures could reduce activity of…”
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Discovery of thermophilic Bacillales using reduced-representation genotyping for identification
Published in BMC microbiology (13-05-2020)“…This study demonstrates the use of reduced-representation genotyping to provide preliminary identifications for thermophilic bacterial isolates. The approach…”
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Sex Reversal in Reptiles: Reproductive Oddity or Powerful Driver of Evolutionary Change?
Published in Sexual development (01-01-2016)“…Is sex a product of genes, the environment, or both? In this review, we describe the diversity of sex-determining mechanisms in reptiles, with a focus on…”
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Effects of natural nest temperatures on sex reversal and sex ratios in an Australian alpine skink
Published in Scientific reports (11-10-2021)“…Altered climate regimes have the capacity to affect the physiology, development, ecology and behaviour of organisms dramatically, with consequential changes in…”
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Gene expression of male pathway genes sox9 and amh during early sex differentiation in a reptile departs from the classical amniote model
Published in BMC genomics (05-05-2023)“…Sex determination is the process whereby the bipotential embryonic gonads become committed to differentiate into testes or ovaries. In genetic sex…”
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A return-on-investment approach for prioritization of rigorous taxonomic research needed to inform responses to the biodiversity crisis
Published in PLoS biology (01-06-2021)“…Global biodiversity loss is a profound consequence of human activity. Disturbingly, biodiversity loss is greater than realized because of the unknown number of…”
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Temperature Sex Reversal Implies Sex Gene Dosage in a Reptile
Published in Science (American Association for the Advancement of Science) (20-04-2007)“…Sex in reptiles is determined by genes on sex chromosomes or by incubation temperature. Previously these two modes were thought to be distinct, yet we show…”
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Anchoring genome sequence to chromosomes of the central bearded dragon (Pogona vitticeps) enables reconstruction of ancestral squamate macrochromosomes and identifies sequence content of the Z chromosome
Published in BMC genomics (10-06-2016)“…Squamates (lizards and snakes) are a speciose lineage of reptiles displaying considerable karyotypic diversity, particularly among lizards. Understanding the…”
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The ends of a continuum: genetic and temperature-dependent sex determination in reptiles
Published in BioEssays (01-06-2004)“…Two prevailing paradigms explain the diversity of sex‐determining modes in reptiles. Many researchers, particularly those who study reptiles, consider genetic…”
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Developmental asynchrony and antagonism of sex determination pathways in a lizard with temperature-induced sex reversal
Published in Scientific reports (05-10-2018)“…Vertebrate sex differentiation follows a conserved suite of developmental events: the bipotential gonads differentiate and shortly thereafter sex specific…”
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omicR: A tool to facilitate BLASTn alignments for sequence data
Published in SoftwareX (01-06-2021)“…Bioinformatics tools for the analysis of sequencing data, are becoming accessible for most scientists. Beginners who are unfamiliar to these tools can be…”
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Highly differentiated ZW sex microchromosomes in the Australian Varanus species evolved through rapid amplification of repetitive sequences
Published in PloS one (01-04-2014)“…Transitions between sex determination systems have occurred in many lineages of squamates and it follows that novel sex chromosomes will also have arisen…”
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