Search Results - "George P. Patrinos"

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    Human genetic factors associated with susceptibility to SARS-CoV-2 infection and COVID-19 disease severity by Anastassopoulou, Cleo, Gkizarioti, Zoi, Patrinos, George P, Tsakris, Athanasios

    Published in Human genomics (22-10-2020)
    “…The emergence of the novel coronavirus in Wuhan, Hubei Province, China, in December 2019 marked the synchronization of the world to a peculiar clock that is…”
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    Updates of the HbVar database of human hemoglobin variants and thalassemia mutations by Giardine, Belinda, Borg, Joseph, Viennas, Emmanouil, Pavlidis, Cristiana, Moradkhani, Kamran, Joly, Philippe, Bartsakoulia, Marina, Riemer, Cathy, Miller, Webb, Tzimas, Giannis, Wajcman, Henri, Hardison, Ross C, Patrinos, George P

    Published in Nucleic acids research (01-01-2014)
    “…HbVar (http://globin.bx.psu.edu/hbvar) is one of the oldest and most appreciated locus-specific databases launched in 2001 by a multi-center academic effort to…”
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    Triangulating nutrigenomics, metabolomics and microbiomics toward personalized nutrition and healthy living by Lagoumintzis, George, Patrinos, George P

    Published in Human genomics (08-12-2023)
    “…The unique physiological and genetic characteristics of individuals influence their reactions to different dietary constituents and nutrients. This notion is…”
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    Discovery of new drug indications for COVID-19: A drug repurposing approach by Kumari, Priyanka, Pradhan, Bikram, Koromina, Maria, Patrinos, George P, Steen, Kristel Van

    Published in PloS one (24-05-2022)
    “…The outbreak of coronavirus health issues caused by COVID-19(SARS-CoV-2) creates a global threat to public health. Therefore, there is a need for effective…”
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    Computational approaches in target identification and drug discovery by Katsila, Theodora, Spyroulias, Georgios A., Patrinos, George P., Matsoukas, Minos-Timotheos

    “…In the big data era, voluminous datasets are routinely acquired, stored and analyzed with the aim to inform biomedical discoveries and validate hypotheses. No…”
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    Gene conversion: mechanisms, evolution and human disease by Chen, Jian-Min, Patrinos, George P, Cooper, David N, Chuzhanova, Nadia, Férec, Claude

    Published in Nature reviews. Genetics (01-10-2007)
    “…Gene conversion, one of the two mechanisms of homologous recombination, involves the unidirectional transfer of genetic material from a 'donor' sequence to a…”
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    Cost-utility analysis and cross-country comparison of pharmacogenomics-guided treatment in colorectal cancer patients participating in the U-PGx PREPARE study by Fragoulakis, Vasileios, Roncato, Rossana, Bignucolo, Alessia, Patrinos, George P., Toffoli, Giuseppe, Cecchin, Erika, Mitropoulou, Christina

    Published in Pharmacological research (01-11-2023)
    “…OBJECTIVESA cost-utility analysis was conducted to evaluate pharmacogenomic (PGx)-guided treatment compared to the standard-of-care intervention among patients…”
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    Krüppeling erythropoiesis: an unexpected broad spectrum of human red blood cell disorders due to KLF1 variants by Perkins, Andrew, Xu, Xiangmin, Higgs, Douglas R., Patrinos, George P., Arnaud, Lionel, Bieker, James J., Philipsen, Sjaak

    Published in Blood (14-04-2016)
    “…Until recently our approach to analyzing human genetic diseases has been to accurately phenotype patients and sequence the genes known to be associated with…”
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    Exploring public genomics data for population pharmacogenomics by Lakiotaki, Kleanthi, Kanterakis, Alexandros, Kartsaki, Evgenia, Katsila, Theodora, Patrinos, George P, Potamias, George

    Published in PloS one (03-08-2017)
    “…Racial and ethnic differences in drug responses are now well studied and documented. Pharmacogenomics research seeks to unravel the genetic underpinnings of…”
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    A qualitative approach to assess the opinion of physicians about the challenges and prospects of pharmacogenomic testing implementation in clinical practice in Greece by Koufaki, Margarita-Ioanna, Patrinos, George P, Vasileiou, Konstantinos Z

    Published in Human genomics (19-07-2024)
    “…Pharmacogenomics (PGx) constitutes an important part of personalized medicine and has several clinical applications. PGx role in clinical practice is known,…”
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    PARC report: health outcomes and value of personalized medicine interventions: impact on patient care by Mitropoulou, Christina, Litinski, Veronika, Kabakchiev, Boyko, Rogers, Sara, P Patrinos, George

    Published in Pharmacogenomics (01-07-2020)
    “…The incorporation of personalized medicine interventions into routine healthcare constitutes an opportunity to improve patients' quality of life, as it…”
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