Search Results - "George, R."

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  1. 1

    The JAK-STAT Pathway at Twenty by Stark, George R., Darnell, James E.

    Published in Immunity (Cambridge, Mass.) (20-04-2012)
    “…We look back on the discoveries that the tyrosine kinases TYK2 and JAK1 and the transcription factors STAT1, STAT2, and IRF9 are required for the cellular…”
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  2. 2

    Targeting the Hepatocyte Growth Factor–cMET Axis in Cancer Therapy by BLUMENSCHEIN, George R, MILLS, Gordon B, GONZALEZ-ANGULO, Ana M

    Published in Journal of clinical oncology (10-09-2012)
    “…The hepatocyte growth factor (HGF) and its receptor, the transmembrane tyrosine kinase cMET, promote cell proliferation, survival, motility, and invasion as…”
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  3. 3

    The Antifungal Pipeline: Fosmanogepix, Ibrexafungerp, Olorofim, Opelconazole, and Rezafungin by Hoenigl, Martin, Sprute, Rosanne, Egger, Matthias, Arastehfar, Amir, Cornely, Oliver A., Krause, Robert, Lass-Flörl, Cornelia, Prattes, Juergen, Spec, Andrej, Thompson, George R., Wiederhold, Nathan, Jenks, Jeffrey D.

    Published in Drugs (New York, N.Y.) (01-10-2021)
    “…The epidemiology of invasive fungal infections is changing, with new populations at risk and the emergence of resistance caused by the selective pressure from…”
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    Aspergillosis: Epidemiology, Diagnosis, and Treatment by Cadena, Jose, Thompson, 3rd, George R, Patterson, Thomas F

    “…The spectrum of disease produced by Aspergillus species ranges from allergic syndromes to chronic pulmonary conditions and invasive infections. Invasive…”
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  6. 6

    P2X7 receptor regulation of non‐classical secretion from immune effector cells by Dubyak, George R.

    Published in Cellular microbiology (01-11-2012)
    “…Summary P2X7 receptors (P2X7R) are extracellular ATP‐gated ion channels expressed in the immune effector cells that carry out critical protective responses…”
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  7. 7

    50th Anniversary Perspective: Functional Nanoparticles from the Solution Self-Assembly of Block Copolymers by Tritschler, Ulrich, Pearce, Sam, Gwyther, Jessica, Whittell, George R, Manners, Ian

    Published in Macromolecules (09-05-2017)
    “…This Perspective outlines recent advances concerning the formation and potential uses of block copolymer micelles, a class of soft-matter-based nanoparticles…”
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  8. 8

    Aspiring Antifungals: Review of Current Antifungal Pipeline Developments by Gintjee, Thomas J, Donnelley, Monica A, Thompson, 3rd, George R

    Published in Journal of fungi (Basel) (01-03-2020)
    “…Invasive fungal infections are associated with significant morbidity and mortality, and their management is restricted to a variety of agents from five…”
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  9. 9

    Advances in high-speed atomic force microscopy (HS-AFM) reveal dynamics of transmembrane channels and transporters by Heath, George R, Scheuring, Simon

    Published in Current opinion in structural biology (01-08-2019)
    “…•HS-AFM detects conformational changes of unlabeled membrane proteins.•In situ responses to pH, ligands, temperature and light can be visualized.•Developments…”
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  10. 10

    Canonical Microcircuits for Predictive Coding by Bastos, Andre M., Usrey, W. Martin, Adams, Rick A., Mangun, George R., Fries, Pascal, Friston, Karl J.

    Published in Neuron (Cambridge, Mass.) (21-11-2012)
    “…This Perspective considers the influential notion of a canonical (cortical) microcircuit in light of recent theories about neuronal processing. Specifically,…”
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    Evidence for antibody as a protective correlate for COVID-19 vaccines by Earle, Kristen A., Ambrosino, Donna M., Fiore-Gartland, Andrew, Goldblatt, David, Gilbert, Peter B., Siber, George R., Dull, Peter, Plotkin, Stanley A.

    Published in Vaccine (22-07-2021)
    “…A correlate of protection (CoP) is urgently needed to expedite development of additional COVID-19 vaccines to meet unprecedented global demand. To assess…”
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  12. 12

    Wildfire smoke, a potential infectious agent by Kobziar, Leda N, Thompson, 3rd, George R

    “…Bacteria and fungi are transported in wildland fire smoke emissions Wildfires over the past 3 years have resulted in lengthy episodes of smoke inundation…”
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  13. 13

    Neutrophil P2X7 receptors mediate NLRP3 inflammasome-dependent IL-1β secretion in response to ATP by Karmakar, Mausita, Katsnelson, Michael A., Dubyak, George R., Pearlman, Eric

    Published in Nature communications (15-02-2016)
    “…Although extracellular ATP is abundant at sites of inflammation, its role in activating inflammasome signalling in neutrophils is not well characterized. In…”
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  14. 14

    Exciting red and competent blue: the importance of color in marketing by Labrecque, Lauren I., Milne, George R.

    “…From beverages to consumer electronics, marketers are using color in innovative ways. Despite this, little academic research has investigated the role that…”
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    Aspergillus Infections by Thompson, George R, Young, Jo-Anne H

    Published in The New England journal of medicine (14-10-2021)
    “…Aspergillosis is an opportunistic fungal infection that poses a particular risk for patients with neutrophil defects and causes diverse clinical syndromes…”
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  16. 16

    High-speed AFM height spectroscopy reveals µs-dynamics of unlabeled biomolecules by Heath, George R., Scheuring, Simon

    Published in Nature communications (26-11-2018)
    “…Dynamics are fundamental to the functions of biomolecules and can occur on a wide range of time and length scales. Here we develop and apply high-speed AFM…”
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    Coccidioidomycosis by Stockamp, Nathan W., MD, Thompson, George R., MD

    “…Coccidioides immitis and C posadasii are pathogenic dimorphic fungi responsible for causing coccidioidomycosis in the Southwestern United States and Central…”
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    HIV latency is reversed by ACSS2-driven histone crotonylation by Jiang, Guochun, Nguyen, Don, Archin, Nancie M, Yukl, Steven A, Méndez-Lagares, Gema, Tang, Yuyang, Elsheikh, Maher M, Thompson, 3rd, George R, Hartigan-O'Connor, Dennis J, Margolis, David M, Wong, Joseph K, Dandekar, Satya

    Published in The Journal of clinical investigation (01-03-2018)
    “…Eradication of HIV-1 (HIV) is hindered by stable viral reservoirs. Viral latency is epigenetically regulated. While the effects of histone acetylation and…”
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  20. 20

    Long-range exciton transport in conjugated polymer nanofibers prepared by seeded growth by Jin, Xu-Hui, Price, Michael B, Finnegan, John R, Boott, Charlotte E, Richter, Johannes M, Rao, Akshay, Menke, S Matthew, Friend, Richard H, Whittell, George R, Manners, Ian

    “…Easily processed materials with the ability to transport excitons over length scales of more than 100 nanometers are highly desirable for a range of…”
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