Search Results - "George, Margaret D"
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role for Orai in TRPC-mediated Ca²⁺ entry suggests that a TRPC:Orai complex may mediate store and receptor operated Ca²⁺ entry
Published in Proceedings of the National Academy of Sciences - PNAS (03-03-2009)“…TRPC and Orai proteins have both been proposed to form Ca²⁺-selective, store-operated calcium entry (SOCE) channels that are activated by store-depletion with…”
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p38 mitogen-activated protein kinase interacts with vinculin at focal adhesions during fatty acid-stimulated cell adhesion
Published in Biochemistry and cell biology (01-12-2013)“…Arachidonic acid stimulates cell adhesion by activating α2β1 integrins in a process that depends on protein kinases, including p38 mitogen activated protein…”
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15‐Lipoxygenase‐1 activates tumor suppressor p53 independent of enzymatic activity
Published in International journal of cancer (15-12-2008)“…15‐LOX‐1 and its metabolites are involved in colorectal cancer. Recently, we reported that 15‐LOX‐1 overexpression in HCT‐116 human colorectal cancer cells…”
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P-selectin activates integrin-mediated colon carcinoma cell adhesion to fibronectin
Published in Experimental cell research (10-12-2006)“…During hematogenous cancer metastasis, tumor cells separate from a primary mass, enter the bloodstream, disperse throughout the body, migrate across vessel…”
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Expression of Cornifin in Squamous Differentiating Epithelial Tissues, Including Psoriatic and Retinoic Acid-Treated Skin
Published in Journal of investigative dermatology (01-09-1993)“…The expression of cornifin, a putative cross-linked envelope precursor, was investigated in several squamous differentiating tissues by in situ hybridization…”
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Cornifin, a Cross-Linked Envelope Precursor in Keratinocytes that is Down- Regulated by Retinoids
Published in Proceedings of the National Academy of Sciences - PNAS (15-11-1992)“…In this study, we have characterized the cDNA clone SQ37 that was isolated previously from a rabbit squamous cell library. The gene encodes a 14-kDa protein…”
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A role for Orai in TRPC-mediated Ca super(2+) entry suggests that a TRPC:Orai complex may mediate store and receptor operated Ca super(2+) entry
Published in Proceedings of the National Academy of Sciences - PNAS (03-03-2009)“…TRPC and Orai proteins have both been proposed to form Ca super(2+)-selective, store-operated calcium entry (SOCE) channels that are activated by…”
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Journal Article -
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A role for Orai in TRPC-mediated Ca 2+ entry suggests that a TRPC:Orai complex may mediate store and receptor operated Ca 2+ entry
Published in Proceedings of the National Academy of Sciences - PNAS (03-03-2009)“…TRPC and Orai proteins have both been proposed to form Ca 2+ -selective, store-operated calcium entry (SOCE) channels that are activated by store-depletion…”
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Journal Article -
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A role for Orai in TRPC-mediated Ca^sup 2+^ entry suggests that a TRPC:Orai complex may mediate store and receptor operated Ca^sup 2+^ entry
Published in Proceedings of the National Academy of Sciences - PNAS (03-03-2009)“…TRPC and Orai proteins have both been proposed to form ...-selective, store-operated calcium entry (SOCE) channels that are activated by store-depletion with…”
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Journal Article -
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role for Orai in TRPC-mediated Ca²⺠entry suggests that a TRPC:Orai complex may mediate store and receptor operated Ca²⺠entry
Published in Proceedings of the National Academy of Sciences - PNAS (2009)“…TRPC and Orai proteins have both been proposed to form Ca²âº-selective, store-operated calcium entry (SOCE) channels that are activated by store-depletion…”
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Journal Article -
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Identification of a new squamous cell differentiation marker and its suppression by retinoids
Published in Journal of cellular physiology (01-04-1992)“…Rabbit tracheobronchial epithelial cells (RbTE) can undergo squamous cell differentiation under defined culture conditions and, therefore, have been used as a…”
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Positive and negative regulation of proliferation and differentiation in tracheobronchial epithelial cells
Published in The American review of respiratory disease (01-12-1990)“…The lung (in particular the bronchial epithelium) is a major site for tumor formation in humans. Environmental factors in conjunction with genetic factors are…”
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Expression of nuclear retinoic acid receptors in normal tracheobronchial cells and in lung carcinoma cells
Published in Experimental cell research (01-07-1991)“…Retinoids are important regulators of the growth and differentiation of tracheobronchial epithelial cells. To determine the mechanism of action of retinoids in…”
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Regulation of transglutaminase type II by transforming growth factor-β1 in normal and transformed human epidermal keratinocytes
Published in The Journal of biological chemistry (05-07-1990)Get full text
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Retinoic acid receptors as regulators of human epidermal keratinocyte differentiation
Published in Molecular endocrinology (Baltimore, Md.) (01-05-1992)“…To examine the role of nuclear retinoic acid (RA) receptors (RARs) in the regulation of squamous differentiation in normal human epidermal keratinocytes…”
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Induction of extracellular matrix gene expression in normal human keratinocytes by transforming growth factor beta is altered by cellular differentiation
Published in Experimental cell research (01-03-1991)“…Changes in epithelial substrate have been related to the cellular capacity for proliferation and to changes in cellular behavior. The effect of TGF beta 1 on…”
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Regulation of type I and type II transglutaminase in normal human bronchial epithelial and lung carcinoma cells
Published in American journal of respiratory cell and molecular biology (01-07-1992)“…In cultured, undifferentiated normal human bronchial epithelial (HBE) cells, transglutaminase activity was localized predominantly in the cytosolic fraction of…”
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The role of protein glycosylation inhibitors in the prevention of metastasis and therapy of cancer
Published in Cancer detection and prevention (01-01-1998)“…Oligosaccharide moieties of cell-surface glycoproteins are thought to be involved in recognition events during cancer metastasis and invasion. Swainsonine, an…”
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Identification and Characterization of Nuclear Retionic Acid-Binding Activity in Human Myeloblastic Leukemia HL-60 Cells
Published in Proceedings of the National Academy of Sciences - PNAS (01-08-1989)“…Specific [3H]retinoic acid (RA)-binding sites in nuclear and cytosolic extracts prepared from human myeloblastic leukemia HL-60 cells have been detected by…”
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