Search Results - "George, Kerry A"
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Challenges to the central nervous system during human spaceflight missions to Mars
Published in Journal of neurophysiology (01-05-2020)“…Space travel presents a number of environmental challenges to the central nervous system, including changes in gravitational acceleration that alter the…”
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2
Haplotype diversity and sequence heterogeneity of human telomeres
Published in Genome research (01-07-2021)“…Telomeres are regions of repetitive nucleotide sequences capping the ends of eukaryotic chromosomes that protect against deterioration, and whose lengths can…”
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Temporal Telomere and DNA Damage Responses in the Space Radiation Environment
Published in Cell reports (Cambridge) (08-12-2020)“…Telomeres, repetitive terminal features of chromosomes essential for maintaining genome integrity, shorten with cell division, lifestyle factors and stresses,…”
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Relative Biological Effectiveness of HZE Particles for Chromosomal Exchanges and Other Surrogate Cancer Risk Endpoints
Published in PloS one (25-04-2016)“…The biological effects of high charge and energy (HZE) particle exposures are of interest in space radiation protection of astronauts and cosmonauts, and…”
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Physical and Biological Organ Dosimetry Analysis for International Space Station Astronauts
Published in Radiation research (01-07-2008)“…Cucinotta, F. A., Kim, M-H. Y., Willingham, V. and George, K. A. Physical and Biological Organ Dosimetry Analysis for International Space Station Astronauts…”
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Induction of Chromosomal Aberrations at Fluences of Less Than One HZE Particle per Cell Nucleus
Published in Radiation research (01-10-2014)“…The assumption of a linear dose response used to describe the biological effects of high-LET radiation is fundamental in radiation protection methodologies. We…”
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Biological Effectiveness of Accelerated Particles for the Induction of Chromosome Damage: Track Structure Effects
Published in Radiation research (01-07-2013)“…We have investigated how radiation quality affects the induction of chromosomal aberrations in human cells. Human lymphocytes were irradiated in vitro with…”
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Biological Effectiveness of Accelerated Protons for Chromosome Exchanges
Published in Frontiers in oncology (19-10-2015)“…We have investigated chromosome exchanges induced in human cells by seven different energies of protons (5-2500 MeV) with LET values ranging from 0.2 to 8…”
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Telomere Length Dynamics and DNA Damage Responses Associated with Long-Duration Spaceflight
Published in Cell reports (Cambridge) (08-12-2020)“…Telomere length dynamics and DNA damage responses were assessed before, during, and after one-year or shorter duration missions aboard the International Space…”
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Ad Astra - telomeres in space
Published in International journal of radiation biology (04-03-2022)“…My journey to the stars began as I - along with the whole world - stood still and watched Neil Armstrong take those first small steps on the Moon. Fast forward…”
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Cytogenetic biodosimetry using the blood lymphocytes of astronauts
Published in Acta astronautica (01-11-2013)“…Cytogenetic analysis of peripheral blood lymphocytes is the most sensitive and reliable method currently available for in vivo assessment of the biological…”
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Dose Response of γ Rays and Iron Nuclei for Induction of Chromosomal Aberrations in Normal and Repair-Deficient Cell Lines
Published in Radiation research (01-06-2009)“…George, K. A., Hada, M., Jackson, L. J., Elliott, T., Kawata, T., Pluth, J. M. and Cucinotta, F. A. Dose Response for c Rays and Iron Nuclei for Induction of…”
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AT cells are not radiosensitive for simple chromosomal exchanges at low dose
Published in Mutation research (01-11-2011)“…Cells deficient in ATM (product of the gene that is mutated in ataxia telangiectasia patients) or NBS (product of the gene mutated in the Nijmegen breakage…”
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Evaluation of skin cancer risk for lunar and Mars missions
Published in Advances in space research (2006)“…Methods used to estimate the probability of excess incidence of skin cancer from space radiation exposure must take into consideration the variability of dose…”
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31. Assessing telomere length and chromosome aberrations in twin and unrelated astronauts
Published in Cancer genetics (01-08-2018)Get full text
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Dose Response of g Rays and Iron Nuclei for Induction of Chromosomal Aberrations in Normal and Repair-Deficient Cell Lines
Published in Radiation research (01-06-2009)“…George, K. A., Hada, M., Jackson, L. J., Elliott, T., Kawata, T., Pluth, J. M. and Cucinotta, F. A. Dose Response for c Rays and Iron Nuclei for Induction of…”
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About the Contributors
Published in Safety Design for Space Systems (2009)Get full text
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