Search Results - "George, JA"
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Vitamin D [25(OH)D] and 1,25(OH)2D serum concentrations in patients tested at the Charlotte Maxeke Johannesburg Academic Hospital
Published in JEMDSA : the journal of endocrinology, metabolism and diabetes of South Africa (01-07-2021)“…There has been a significant increase in vitamin D [25(OH)D] testing in recent years. To describe the number of tests, concentrations for 25(OH)D and 1,25(OH)…”
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Antibody to CD40 ligand inhibits both humoral and cellular immune responses to adenoviral vectors and facilitates repeated administration to mouse airway
Published in Gene therapy (01-06-1997)“…Adenoviral vectors have been used successfully to transfer the human CFTR cDNA to respiratory epithelium in animal models and to CF patients in vivo. However,…”
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Should haemoglobin A1c be used for the diagnosis of diabetes mellitus in South Africa?
Published in JEMDSA : the journal of endocrinology, metabolism and diabetes of South Africa (01-12-2011)“…Diabetes is an important medical problem in sub-Saharan Africa. It has traditionally been diagnosed by means of fasting plasma glucose, random blood glucose or…”
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Motor Control and Sensory Feedback Enhance Prosthesis Embodiment and Reduce Phantom Pain After Long-Term Hand Amputation
Published in Frontiers in human neuroscience (21-09-2018)“…We quantified prosthesis embodiment and phantom pain reduction associated with motor control and sensory feedback from a prosthetic hand in one human with a…”
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Practical and Robust Identification of Molecular Subtypes in Colorectal Cancer by Immunohistochemistry
Published in Clinical cancer research (15-01-2017)“…Recent transcriptomic analyses have identified four distinct molecular subtypes of colorectal cancer with evident clinical relevance. However, the requirement…”
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PD-1 inhibits T-cell receptor induced phosphorylation of the ZAP70/CD3ζ signalosome and downstream signaling to PKCθ
Published in FEBS letters (10-09-2004)“…Engagement of the immunoinhibitory receptor, programmed death-1 (PD-1) attenuates T-cell receptor (TCR)-mediated activation of IL-2 production and T-cell…”
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Longitudinal changes in vitamin D and its metabolites in pregnant South Africans
Published in The Journal of steroid biochemistry and molecular biology (01-09-2021)“…•25(OH)D, 24,25(OH)2D and cholecalciferol measured in a single run.•Reduced cholecalciferol and 24,25(OH)2D levels maintain 25(OH)D levels in pregnancy.•VDBP…”
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Gene therapy progress and prospects: adenoviral vectors
Published in Gene therapy (01-07-2003)“…In September 1999, the perceptions of the use of adenoviral (Ad) vectors for gene therapy were altered when a patient exposed via the hepatic artery to a high…”
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L-DOPA-induced dysregulation of extrastriatal dopamine and serotonin and affective symptoms in a bilateral rat model of Parkinson’s disease
Published in Neuroscience (30-08-2012)“…Highlights ► A novel bilateral rat model of Parkinson’s disease resulted in loss of approximately 80% striatal DA. ► Chronic L-DOPA-induced time-dependent…”
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Sample Entropy Analysis of EEG Signals via Artificial Neural Networks to Model Patients’ Consciousness Level Based on Anesthesiologists Experience
Published in BioMed research international (01-01-2015)“…Electroencephalogram (EEG) signals, as it can express the human brain’s activities and reflect awareness, have been widely used in many research and medical…”
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Fukushima ^sup 137^Cs at the base of planktonic food webs off Japan
Published in Deep-sea research. Part I, Oceanographic research papers (01-12-2015)“…The potential bioaccumulation of 137Cs in marine food webs off Japan became a concern following the release of radioactive contaminants from the damaged…”
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Src tyrosine kinase and multidrug resistance protein-1 inhibitions act independently but cooperatively to restore paclitaxel sensitivity to paclitaxel-resistant ovarian cancer cells
Published in Cancer research (Chicago, Ill.) (15-11-2005)“…Src tyrosine kinase has been found to be overexpressed in both mouse and human ovarian cancer cells as well as in human primary ovarian cancers. Furthermore,…”
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Fukushima 137Cs at the base of planktonic food webs off Japan
Published in Deep-sea research. Part I, Oceanographic research papers (01-12-2015)“…The potential bioaccumulation of 137Cs in marine food webs off Japan became a concern following the release of radioactive contaminants from the damaged…”
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Early life exposure to allergen and ozone results in altered development in adolescent rhesus macaque lungs
Published in Toxicology and applied pharmacology (15-02-2015)“…In rhesus macaques, previous studies have shown that episodic exposure to allergen alone or combined with ozone inhalation during the first 6months of life…”
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Effects of an ambient level of ozone on primate nasal epithelial mucosubstances. Quantitative histochemistry
Published in The American journal of pathology (01-04-1987)“…Despite the absorption of inhaled oxidant gases by the nasal cavity, little effort has been made to characterize the effects of these oxidants on the nasal…”
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A longitudinal study of the changes in body fat and metabolic parameters in a South African population of HIV-positive patients receiving an antiretroviral therapeutic regimen containing stavudine
Published in AIDS research and human retroviruses (01-08-2009)“…The aim of this study was to determine the patterns of change in body fat and metabolic parameters in a South African cohort on a first line ART regimen…”
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The effect of intravenous opioid patient-controlled analgesia with and without background infusion on respiratory depression: a meta-analysis
Published in Journal of opioid management (01-01-2010)“…Although the addition of a background infusion for intravenous patient-controlled analgesia (IV-PCA) has been identified as a risk factor for the development…”
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Two retrotransposons maintain telomeres in Drosophila
Published in Chromosome research (01-07-2005)“…Telomeres across the genus Drosophila are maintained, not by telomerase, but by two non-LTR retrotransposons, HeT-A and TART, that transpose specifically to…”
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