Search Results - "George, Irene"
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Circulating tumor cells as an emerging tool in cancer therapy
Published in Frontiers in bioscience (01-01-2020)“…Majority of the cancer-related deaths are related to metastasis during which cancer cells invade the surrounding tissues, enter (intravasation) and exit…”
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Pan-cancer quantitation of epithelial-mesenchymal transition dynamics using parallel reaction monitoring-based targeted proteomics approach
Published in Journal of translational medicine (11-02-2022)“…Epithelial-mesenchymal transition (EMT) is a dynamic and complex cellular process that is known to be hijacked by cancer cells to facilitate invasion,…”
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Urinary glycoproteomic profiling of non-muscle invasive and muscle invasive bladder carcinoma patients reveals distinct N-glycosylation pattern of CD44, MGAM, and GINM1
Published in Oncotarget (25-08-2020)“…Clinical management of bladder carcinomas (BC) remains a major challenge and demands comprehensive multi-omics analysis for better stratification of the…”
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Circulating markers in metastatic cancer: new perspectives
Published in Frontiers in bioscience (Landmark. Print) (30-12-2021)Get full text
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Somatic Mutations Profile of a Young Patient With Metastatic Urothelial Carcinoma Reveals Mutations in Genes Involved in Ion Channels
Published in Frontiers in oncology (29-05-2019)“…Urothelial carcinoma is the most common malignancy of the bladder and is primarily considered as a disease of the elderly. Studies that address bladder tumor…”
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Integrated proteomics and phosphoproteomics revealed druggable kinases in neoadjuvant chemotherapy resistant tongue cancer
Published in Frontiers in cell and developmental biology (28-10-2022)“…Tongue squamous cell carcinoma is an aggressive oral cancer with a high incidence of metastasis and poor prognosis. Most of the oral cavity cancer patients…”
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Ab Initio Prediction of the Diversity of Second Harmonic Generation from Pharmaceutically Relevant Materials
Published in Crystal growth & design (04-02-2015)“…A model for predicting the anticipated second harmonic generation (SHG) activity of crystalline active pharmaceutical ingredients (APIs) was developed based on…”
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Insights into therapy resistance in cervical cancer
Published in Advances in cancer biology - metastasis (01-12-2022)“…Treatment failure is one of the main hurdles in treating cervical cancer, despite significant breakthroughs in both conventional and targeted therapy. The…”
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NUT-midline carcinoma of the lung with rare BRD3-NUTM1 fusion
Published in Cancer research, statistics, and treatment (Online) (01-01-2024)Get full text
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Clinical phosphoproteomics reveals aberrant signalling pathways and kinases in treatment-resistant cervical cancer
Published in Journal of clinical oncology (01-06-2024)“…e17529 Background: Cisplatin-based concurrent chemoradiation therapy (CCRT) is the standard for locally advanced cervical cancer. While cisplatin stands out as…”
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Predictive molecular markers of chemoradiation resistance in cervical cancer
Published in Journal of clinical oncology (01-06-2023)“…e17505 Background: Cisplatin based concurrent chemoradiation therapy (CCRT) has been recognized as the standard treatment for locally advanced cervical cancer…”
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Landscape of genomic alterations in patients with chemoradiation resistant cervical cancer using whole-genome sequencing
Published in Journal of clinical oncology (01-06-2024)“…e17531 Background: Cervical cancer is a pressing global health concern and ranks as the second most prevalent female malignancy in India. Unfortunately, 80% of…”
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Synergistic Suppression of NF1 Malignant Peripheral Nerve Sheath Tumor Cell Growth in Culture and Orthotopic Xenografts by Combinational Treatment with Statin and Prodrug Farnesyltransferase Inhibitor PAMAM G4 Dendrimers
Published in Cancers (23-12-2023)“…Neurofibromatosis type 1 (NF1) is a disorder in which RAS is constitutively activated due to the loss of the Ras-GTPase-activating activity of neurofibromin…”
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Rare compound mutation of EGFR L858R and E709A identified in both solid tumor and liquid biopsy of a lung adenocarcinoma patient
Published in Medical Reports (01-08-2024)“…Non-small cell lung cancer (NSCLC) is the most common subtype of lung cancer. Among NSCLC, lung adenocarcinoma is majorly characterized by driver activating…”
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De novo acute myeloid leukemia with 20–29% blasts is less aggressive than acute myeloid leukemia with ≥30% blasts in older adults: a Bone Marrow Pathology Group study
Published in American journal of hematology (01-11-2014)“…It is controversial whether acute myeloid leukemia (AML) patients with 20–29% bone marrow (BM) blasts, formerly referred to as refractory anemia with excess…”
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The French, English and a Fish: How They Transformed the Island of Newfoundland, 1696-1713
Published 01-01-2016“…Newfoundland is an island on the east coast of Canada that is mostly forgotten to the study of history. This paper looks in depth at the fighting between…”
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De novo acute myeloid leukemia with 20–29% blasts is less aggressive than acute myeloid leukemia with ≥30% blasts in older adults: a B one M arrow P athology G roup study
Published in American journal of hematology (01-11-2014)“…It is controversial whether acute myeloid leukemia (AML) patients with 20–29% bone marrow (BM) blasts, formerly referred to as refractory anemia with excess…”
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The concept of anomalous cerebral lateralization in Klinefelter syndrome
Published in Applied neuropsychology (01-04-2010)“…Klinefelter syndrome (KS) is a genetic disorder in males characterized by the presence of an extra X chromosome. Its most consistent endocrinological…”
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