Search Results - "George, Claudene J."

Brain Renin-Angiotensin System at the Intersect of Physical and Cognitive Frailty by Cosarderelioglu, Caglar, Nidadavolu, Lolita S, George, Claudene J, Oh, Esther S, Bennett, David A, Walston, Jeremy D, Abadir, Peter M

“…The renin-angiotensin system (RAS) was initially considered to be part of the endocrine system regulating water and electrolyte balance, systemic vascular…”
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The effect of diabetes on prefrontal cortex activation patterns during active walking in older adults by Holtzer, Roee, George, Claudene J., Izzetoglu, Meltem, Wang, Cuiling

“…•We evaluated the effect of diabetes on cortical control of gait in older adults.•Diabetes was associated with poorer walking performance.•Diabetes attenuated…”
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Metformin use and mortality and length of stay among hospitalized patients with type 2 diabetes and COVID-19: A multiracial, multiethnic, urban observational study by Miao, Emily, Zhang, Kaleena, Liu, Jianyou, Lin, Juan, Yoo, Donna, George, Claudene J

“…Diabetes mellitus is a common comorbidity among patients with coronavirus disease 2019 (COVID-19). Diabetic patients with COVID-19 have a two-fold increased…”
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Coronavirus Related Mortality in the Geriatrics Ambulatory Practice by George, Claudene J., Guo, Alice

“…Background Older adults often have atypical presentations of common diseases and COVID-19 is no exception. Presentations range from asymptomatic to…”
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Gait Performance in Hypertensive Patients on Angiotensin-Converting Enzyme Inhibitors by George, Claudene J., MD, RPh, Verghese, Joe, MBBS, MS

“…Abstract Objective To examine the relationship between angiotensin-converting enzyme inhibitor (ACEI) use and gait performance in older adults. Design…”
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Motoric Cognitive Risk Syndrome in Polypharmacy by George, Claudene J., Verghese, Joe

“…OBJECTIVES Risk factors for motoric cognitive risk syndrome (MCR), a predementia syndrome characterized by slow gait and cognitive complaints, have been…”
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The effect of polypharmacy on prefrontal cortex activation during single and dual task walking in community dwelling older adults by George, Claudene J., Verghese, Joe, Izzetoglu, Meltem, Wang, Cuiling, Holtzer, Roee

“…Changes in Hb02 levels (Y-axis-expressed in micromolar units), and tasks from Normal Walk(STW) and Alpha to Walk-While-Talk(DTW) as a function of polypharmacy…”
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Higher Angiotensin II Type 1 Receptor Levels and Activity in the Postmortem Brains of Older Persons with Alzheimer’s Dementia by Cosarderelioglu, Caglar, Nidadavolu, Lolita S, George, Claudene J, Marx-Rattner, Ruth, Powell, Laura, Xue, Qian-Li, Tian, Jing, Salib, Joy, Oh, Esther S, Ferrucci, Luigi, Dincer, Pervin, Bennett, David A, Walston, Jeremy D, Abadir, Peter M

“…Abstract Aging is a key risk factor in Alzheimer’s dementia (AD) development and progression. The primary dementia-protective benefits of angiotensin II…”
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Appropriate proton pump inhibitor use among older adults: a retrospective chart review by George, Claudene J, Korc, Beatriz, Ross, Joseph S

“…Proton pump inhibitors (PPIs) are widely used, but not always with a clear indication. Nonindicated use is of particular concern among older adults, who may…”
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Higher angiotensin II type 1 receptor (AT1R) levels and activity in the postmortem brains of older persons with Alzheimer’s disease by Cosarderelioglu, Caglar, George, Claudene J, Marx‐Rattner, Ruth, Xue, Qian‐Li, Tian, Jing, Oh, Esther S, Ferrucci, Luigi, Bennett, David A., Walston, Jeremy, Abadir, Peter

“…Background Alzheimer’s disease (AD) is the most common cause of dementia. Although multiple potential etiologies have been proposed, no clear aging‐related…”
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Angiotensin receptor blocker use is associated with upregulation of the memory-protective angiotensin type 4 receptor (AT4R) in the postmortem brains of individuals without cognitive impairment by Cosarderelioglu, Caglar, Nidadavolu, Lolita S., George, Claudene J., Marx-Rattner, Ruth, Powell, Laura, Xue, Qian-Li, Tian, Jing, Oh, Esther S., Ferrucci, Luigi, Dincer, Pervin, Bennett, David A., Walston, Jeremy D., Abadir, Peter M.

“…The reported primary dementia-protective benefits of angiotensin II type 1 receptor (AT 1 R) blockers (ARB) are believed, at least in part, to arise from…”
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Geriatrics Medication Management Rounds: A Novel Approach to Teaching Rational Prescribing with the Use of the Medication Screening Questionnaire by George, Claudene J., Jacobs, Laurie G.

“…Prescribing for older adults has become increasingly complex as treatment regimens have intensified, and the use of herbal and over‐the‐counter medications has…”
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Centrally Acting ACE Inhibitor Use and Physical Performance in Older Adults by George, C J, Hall, C B, Weiss, E F, Verghese, J, Neptune, E, Abadir, P

“…There is conflicting evidence regarding the role of angiotensin-converting enzyme inhibitors and physical function. While some studies show improvements in…”
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Patent Foramen Ovale Presenting as Persistent Hypoxemia in a 76-year-old Male with Pneumonia by Navia, Ramiro Osvaldo, MD, Navia, Ramiro O., MD, George, Claudene J., MD

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Angiotensin Receptor Blockers Upregulate Angiotensin Type 4 Receptor in Brains of Cognitively Intact Individuals by Cosarderelioglu, Caglar, George, Claudene J, Xue, Qian-Li, Oh, Esther, Ferrucci, Luigi, Bennett, David, Walston, Jeremy, Abadir, Peter M

“…Abstract The primary dementia-protective benefits of Angiotensin receptor type 1 (AT1R) blockers (ARBs) are believed to arise from systemic effects on blood…”
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Geriatrics Medication Management Rounds: A Novel Approach to Teaching Rational Prescribing with the Use of the Medication Screening Questionnaire: TEACHING RATIONAL PRESCRIBING by George, Claudene J., Jacobs, Laurie G.

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