Search Results - "George, Ashley F"

SARS-CoV-2-Specific T Cells Exhibit Phenotypic Features of Helper Function, Lack of Terminal Differentiation, and High Proliferation Potential by Neidleman, Jason, Luo, Xiaoyu, Frouard, Julie, Xie, Guorui, Gill, Gurjot, Stein, Ellen S., McGregor, Matthew, Ma, Tongcui, George, Ashley F., Kosters, Astrid, Greene, Warner C., Vasquez, Joshua, Ghosn, Eliver, Lee, Sulggi, Roan, Nadia R.

“…Convalescing coronavirus disease 2019 (COVID-19) patients mount robust T cell responses against SARS-CoV-2, suggesting an important role of T cells in viral…”
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Siglec-9 defines and restrains a natural killer subpopulation highly cytotoxic to HIV-infected cells by Adeniji, Opeyemi S, Kuri-Cervantes, Leticia, Yu, Chenfei, Xu, Ziyang, Ho, Michelle, Chew, Glen M, Shikuma, Cecilia, Tomescu, Costin, George, Ashley F, Roan, Nadia R, Ndhlovu, Lishomwa C, Liu, Qin, Muthumani, Kar, Weiner, David B, Betts, Michael R, Xiao, Han, Abdel-Mohsen, Mohamed

“…Siglec-9 is an MHC-independent inhibitory receptor expressed on a subset of natural killer (NK) cells. Siglec-9 restrains NK cytotoxicity by binding to…”
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Single-cell glycomics analysis by CyTOF-Lec reveals glycan features defining cells differentially susceptible to HIV by Ma, Tongcui, McGregor, Matthew, Giron, Leila, Xie, Guorui, George, Ashley F, Abdel-Mohsen, Mohamed, Roan, Nadia R

“…High-parameter single-cell phenotyping has enabled in-depth classification and interrogation of immune cells, but to date has not allowed for glycan…”
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HIV efficiently infects T cells from the endometrium and remodels them to promote systemic viral spread by Ma, Tongcui, Luo, Xiaoyu, George, Ashley F, Mukherjee, Gourab, Sen, Nandini, Spitzer, Trimble L, Giudice, Linda C, Greene, Warner C, Roan, Nadia R

“…The female reproductive tract (FRT) is the most common site of infection during HIV transmission to women, but viral remodeling complicates characterization of…”
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Deep immunophenotyping reveals endometriosis is marked by dysregulation of the mononuclear phagocytic system in endometrium and peripheral blood by Vallvé-Juanico, Júlia, George, Ashley F, Sen, Sushmita, Thomas, Reuben, Shin, Min-Gyoung, Kushnoor, Divyashree, Vásquez, Joshua J, Vo, Kim Chi, Irwin, Juan C, Roan, Nadia R, Combes, Alexis J, Giudice, Linda C

“…Endometriosis is a chronic, estrogen-dependent disorder where inflammation contributes to disease-associated symptoms of pelvic pain and infertility. Immune…”
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Deep Phenotypic Analysis of Blood and Lymphoid T and NK Cells From HIV+ Controllers and ART-Suppressed Individuals by George, Ashley F, Luo, Xiaoyu, Neidleman, Jason, Hoh, Rebecca, Vohra, Poonam, Thomas, Reuben, Shin, Min-Gyoung, Lee, Madeline J, Blish, Catherine A, Deeks, Steven G, Greene, Warner C, Lee, Sulggi A, Roan, Nadia R

“…T and natural killer (NK) cells are effector cells with key roles in anti-HIV immunity, including in lymphoid tissues, the major site of HIV persistence…”
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Female Genital Fibroblasts Diminish the In Vitro Efficacy of PrEP against HIV by George, Ashley F, McGregor, Matthew, Gingrich, David, Neidleman, Jason, Marquez, Rebecca S, Young, Kyrlia C, Thanigaivelan, Kaavya L, Greene, Warner C, Tien, Phyllis C, Deitchman, Amelia N, Spitzer, Trimble L, Roan, Nadia R

“…The efficacy of HIV pre-exposure prophylaxis (PrEP) is high in men who have sex with men, but much more variable in women, in a manner largely attributed to…”
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Distinctive features of SARS-CoV-2-specific T cells predict recovery from severe COVID-19 by Neidleman, Jason, Luo, Xiaoyu, George, Ashley F., McGregor, Matthew, Yang, Junkai, Yun, Cassandra, Murray, Victoria, Gill, Gurjot, Greene, Warner C., Vasquez, Joshua, Lee, Sulggi A., Ghosn, Eliver, Lynch, Kara L., Roan, Nadia R.

“…Although T cells are likely players in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) immunity, little is known about the phenotypic features of…”
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Advances in HIV Research Using Mass Cytometry by George, Ashley F., Roan, Nadia R.

“…Purpose of Review This review describes how advances in CyTOF and high-dimensional analysis methods have furthered our understanding of HIV transmission,…”
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Protracted yet Coordinated Differentiation of Long-Lived SARS-CoV-2-Specific CD8 + T Cells during Convalescence by Ma, Tongcui, Ryu, Heeju, McGregor, Matthew, Babcock, Benjamin, Neidleman, Jason, Xie, Guorui, George, Ashley F, Frouard, Julie, Murray, Victoria, Gill, Gurjot, Ghosn, Eliver, Newell, Evan W, Lee, Sulggi A, Roan, Nadia R

“…CD8 T cells can potentiate long-lived immunity against COVID-19. We screened longitudinally-sampled convalescent human donors against SARS-CoV-2 tetramers and…”
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Seminal plasma promotes decidualization of endometrial stromal fibroblasts in vitro from women with and without inflammatory disorders in a manner dependent on interleukin-11 signaling by George, Ashley F, Jang, Karen S, Nyegaard, Mette, Neidleman, Jason, Spitzer, Trimble L, Xie, Guorui, Chen, Joseph C, Herzig, Eytan, Laustsen, Anders, Marques de Menezes, Erika G, Houshdaran, Sahar, Pilcher, Christopher D, Norris, Philip J, Jakobsen, Martin R, Greene, Warner C, Giudice, Linda C, Roan, Nadia R

“…Abstract STUDY QUESTION Do seminal plasma (SP) and its constituents affect the decidualization capacity and transcriptome of human primary endometrial stromal…”
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Seminal Plasma-Derived Extracellular-Vesicle Fractions from HIV-Infected Men Exhibit Unique MicroRNA Signatures and Induce a Proinflammatory Response in Cells Isolated from the Female Reproductive Tract by Marques de Menezes, Erika G, Jang, Karen, George, Ashley F, Nyegaard, Mette, Neidleman, Jason, Inglis, Heather C, Danesh, Ali, Deng, Xutao, Afshari, Amirali, Kim, Young H, Billaud, Jean-Noël, Marson, Kara, Pilcher, Christopher D, Pillai, Satish K, Norris, Philip J, Roan, Nadia R

“…The continuing spread of HIV/AIDS is predominantly fueled by sexual exposure to HIV-contaminated semen. Seminal plasma (SP), the liquid portion of semen,…”
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Maternal lactocrine programming of porcine reproductive tract development by Bagnell, Carol A., Ho, Teh‐Yuan, George, Ashley F., Wiley, Anne A., Miller, Dori J., Bartol, Frank F.

“…The lactocrine hypothesis for maternal programming of female reproductive tract development is based on the idea that non‐nutritive, milk‐borne bioactive…”
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Defining age- and lactocrine-sensitive elements of the neonatal porcine uterine microRNA–mRNA interactome by George, Ashley F, Rahman, Kathleen M, Camp, Meredith E, Prasad, Nripesh, Bartol, Frank F, Bagnell, Carol A

“…Factors delivered to offspring in colostrum within 2 days of birth support neonatal porcine uterine development. The uterine mRNA transcriptome is affected by…”
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Neonatal lactocrine deficiency affects the adult porcine endometrial transcriptome at pregnancy day 13 by George, Ashley F, Ho, Teh-Yuan, Prasad, Nripesh, Keel, Brittney N, Miles, Jeremy R, Vallet, Jeffrey L, Bartol, Frank F, Bagnell, Carol A

“…Reproductive performance of female pigs that do not receive sufficient colostrum from birth is permanently impaired. Whether lactocrine deficiency, reflected…”
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Effects of colostrum, feeding method and oral IGF1 on porcine uterine development by George, Ashley F, Rahman, Kathleen M, Miller, Dori J, Wiley, Anne A, Camp, Meredith E, Bartol, Frank F, Bagnell, Carol A

“…Nursing ensures lactocrine delivery of maternally derived, milk-borne bioactive factors to offspring, which affects postnatal development of female…”
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Siglec-9 defines and restrains a natural killer subpopulation highly cytotoxic to HIV-infected cells by Opeyemi S. Adeniji, Leticia Kuri-Cervantes, Chenfei Yu, Ziyang Xu, Michelle Ho, Glen M. Chew, Cecilia Shikuma, Costin Tomescu, Ashley F. George, Nadia R. Roan, Lishomwa C. Ndhlovu, Qin Liu, Kar Muthumani, David B. Weiner, Michael R. Betts, Han Xiao, Mohamed Abdel-Mohsen

“…Siglec-9 is an MHC-independent inhibitory receptor expressed on a subset of natural killer (NK) cells. Siglec-9 restrains NK cytotoxicity by binding to…”
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Maternal Lactocrine Programming of the Porcine Uterus by George, Ashley F

“…Nursing ensures lactocrine delivery of milk-borne bioactive factors to offspring and the lactocrine hypothesis for maternal programming proposes that…”
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