Search Results - "Georgas, Kylie M."
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Global Quantification of Tissue Dynamics in the Developing Mouse Kidney
Published in Developmental cell (28-04-2014)“…Although kidneys of equal size can vary 10-fold in nephron number at birth, discovering what regulates such variation has been hampered by a lack of…”
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Nephron formation adopts a novel spatial topology at cessation of nephrogenesis
Published in Developmental biology (01-12-2011)“…Nephron number in the mammalian kidney is known to vary dramatically, with postnatal renal function directly influenced by nephron complement. What determines…”
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An illustrated anatomical ontology of the developing mouse lower urogenital tract
Published in Development (Cambridge) (15-05-2015)“…Malformation of the urogenital tract represents a considerable paediatric burden, with many defects affecting the lower urinary tract (LUT), genital tubercle…”
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Identification of anchor genes during kidney development defines ontological relationships, molecular subcompartments and regulatory pathways
Published in PloS one (28-02-2011)“…The development of the mammalian kidney is well conserved from mouse to man. Despite considerable temporal and spatial data on gene expression in mammalian…”
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Comparative gene expression analysis of genital tubercle development reveals a putative appendicular Wnt7 network for the epidermal differentiation
Published in Developmental biology (15-08-2010)“…Here we describe the first detailed catalog of gene expression in the developing lower urinary tract (LUT), including epithelial and mesenchymal portions of…”
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Refining transcriptional programs in kidney development by integration of deep RNA-sequencing and array-based spatial profiling
Published in BMC genomics (05-09-2011)“…The developing mouse kidney is currently the best-characterized model of organogenesis at a transcriptional level. Detailed spatial maps have been generated…”
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Use of in situ hybridization to examine gene expression in the embryonic, neonatal, and adult urogenital system
Published in Methods in molecular biology (Clifton, N.J.) (2012)“…Studies into the molecular basis of morphogenesis frequently begin with investigations into gene expression across time and cell type in that organ. One of the…”
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