Search Results - "Georgakilas, Georgios"
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DIANA-TarBase v7.0: indexing more than half a million experimentally supported miRNA:mRNA interactions
Published in Nucleic acids research (28-01-2015)“…microRNAs (miRNAs) are short non-coding RNA species, which act as potent gene expression regulators. Accurate identification of miRNA targets is crucial to…”
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2
Transcriptomic meta-analysis characterizes molecular commonalities between psoriasis and obesity
Published in Genes and immunity (01-06-2024)“…Despite the abundance of epidemiological evidence for the high comorbid rate between psoriasis and obesity, systematic approaches to common inflammatory…”
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DeepTSS: multi-branch convolutional neural network for transcription start site identification from CAGE data
Published in BMC bioinformatics (12-12-2022)“…The widespread usage of Cap Analysis of Gene Expression (CAGE) has led to numerous breakthroughs in understanding the transcription mechanisms. Recent evidence…”
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DIANA-miRGen v4: indexing promoters and regulators for more than 1500 microRNAs
Published in Nucleic acids research (08-01-2021)“…Abstract Deregulation of microRNA (miRNA) expression plays a critical role in the transition from a physiological to a pathological state. The accurate miRNA…”
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Transcriptional repression of lncRNA and miRNA subsets mediated by LRF during erythropoiesis
Published in Journal of molecular medicine (Berlin, Germany) (01-09-2023)“…Non-coding RNA (ncRNA) species, mainly long non-coding RNAs (lncRNAs) and microRNAs (miRNAs) have been currently imputed for lesser or greater involvement in…”
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Solving the transcription start site identification problem with ADAPT-CAGE: a Machine Learning algorithm for the analysis of CAGE data
Published in Scientific reports (21-01-2020)“…Cap Analysis of Gene Expression (CAGE) has emerged as a powerful experimental technique for assisting in the identification of transcription start sites…”
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DIANA-LncBase: experimentally verified and computationally predicted microRNA targets on long non-coding RNAs
Published in Nucleic acids research (01-01-2013)“…Recently, the attention of the research community has been focused on long non-coding RNAs (lncRNAs) and their physiological/pathological implications. As the…”
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Conventional and machine learning approaches as countermeasures against hardware trojan attacks
Published in Microprocessors and microsystems (01-11-2020)“…Every year, the rate at which technology is applied on areas of our everyday life is increasing at a steady pace. This rapid development drives the technology…”
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Multi-branch Convolutional Neural Network for Identification of Small Non-coding RNA genomic loci
Published in Scientific reports (11-06-2020)“…Genomic regions that encode small RNA genes exhibit characteristic patterns in their sequence, secondary structure, and evolutionary conservation…”
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Gene Expression Meta-Analysis of Potential Shared and Unique Pathways between Autoimmune Diseases under Anti-TNFα Therapy
Published in Genes (27-04-2022)“…While anti-TNFα has been established as an effective therapeutic approach for several autoimmune diseases, results from clinical trials have uncovered…”
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aPEAch: Automated Pipeline for End-to-End Analysis of Epigenomic and Transcriptomic Data
Published in Biology (Basel, Switzerland) (02-07-2024)“…With the advent of next-generation sequencing (NGS), experimental techniques that capture the biological significance of DNA loci or RNA molecules have emerged…”
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A Cosine Similarity-Based Method to Infer Variability of Chromatin Accessibility at the Single-Cell Level
Published in Frontiers in genetics (15-08-2018)“…Cellular identity between generations of developing cells is propagated through the epigenome particularly via the accessible parts of the chromatin. It is now…”
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Contribution of the Environment, Epigenetic Mechanisms and Non-Coding RNAs in Psoriasis
Published in Biomedicines (01-08-2022)“…Despite the increasing research and clinical interest in the predisposition of psoriasis, a chronic inflammatory skin disease, the multitude of genetic and…”
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mirPub: a database for searching microRNA publications
Published in Bioinformatics (01-05-2015)“…Identifying, amongst millions of publications available in MEDLINE, those that are relevant to specific microRNAs (miRNAs) of interest based on keyword search…”
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Machine-Learning-Assisted Analysis of TCR Profiling Data Unveils Cross-Reactivity between SARS-CoV-2 and a Wide Spectrum of Pathogens and Other Diseases
Published in Biology (Basel, Switzerland) (19-10-2022)“…During the last two years, the emergence of SARS-CoV-2 has led to millions of deaths worldwide, with a devastating socio-economic impact on a global scale. The…”
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Pharmacogenetic Analysis of the MIR146A rs2910164 and MIR155 rs767649 Polymorphisms and Response to Anti-TNF Treatment in Patients with Crohn's Disease and Psoriasis
Published in Genes (09-02-2023)“…The clinical heterogeneity regarding the response profile of the antitumor necrosis factor (anti-TNF) in patients with Crohn's disease (CD) and psoriasis (PsO)…”
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DIANA-miRPath v3.0: deciphering microRNA function with experimental support
Published in Nucleic acids research (01-07-2015)“…The functional characterization of miRNAs is still an open challenge. Here, we present DIANA-miRPath v3.0 (http://www.microrna.gr/miRPathv3) an online software…”
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Hardware Trojan Classification at Gate-level Netlists based on Area and Power Machine Learning Analysis
Published in 2021 IEEE Computer Society Annual Symposium on VLSI (ISVLSI) (01-07-2021)“…The 21 st century has been characterized by incredible technological advancements. A key factor of this revolution is the ever-growing circuits complexity that…”
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Conference Proceeding -
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Machine Learning for Hardware Trojan Detection: A Review
Published in 2019 Panhellenic Conference on Electronics & Telecommunications (PACET) (01-11-2019)“…Every year, the rate at which technology is applied on areas of our everyday life is increasing at a steady pace. This rapid development drives the technology…”
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Conference Proceeding -
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DIANA-LncBase v2: indexing microRNA targets on non-coding transcripts
Published in Nucleic acids research (04-01-2016)“…microRNAs (miRNAs) are short non-coding RNAs (ncRNAs) that act as post-transcriptional regulators of coding gene expression. Long non-coding RNAs (lncRNAs)…”
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