Search Results - "Geoffrion, M"

E-Business and Management Science: Mutual Impacts (Part 2 of 2) by Geoffrion, Arthur M, Krishnan, Ramayya

“…This concludes a two-part commentary on management science and e-business, the theme of this two-part special issue. After reviewing the topical clusters that…”
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An Introduction to Structured Modeling by Geoffrion, Arthur M

“…The discipline of modeling has advanced only slowly compared to disciplines concerned with analyzing and solving models once they are brought into being…”
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The expression of apolipoprotein B epitopes is normal in LDL of diabetic and end-stage renal disease patients by BRASCHI, S, GEOFFRION, M, NGUYEN, A, GAUDREAU, Y, MILNE, R. W

“…When LDLs are exposed to glucose in vitro, glycation of apolipoprotein B100 (apoB) leads to a loss in its affinity for the LDL receptor and reproducible…”
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E-Business and Management Science: Mutual Impacts (Part 1 of 2) by Geoffrion, Arthur M, Krishnan, Ramayya

“…This begins a two-part commentary on management science and e-business, the theme of this two-part special issue. After explaining the topical clusters that…”
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Extracellular Vesicles Secreted by Atherogenic Macrophages Transfer MicroRNA to Inhibit Cell Migration by Nguyen, My-Anh, Karunakaran, Denuja, Geoffrion, Michele, Cheng, Henry S, Tandoc, Kristofferson, Perisic Matic, Ljubica, Hedin, Ulf, Maegdefessel, Lars, Fish, Jason E, Rayner, Katey J

“…OBJECTIVE—During inflammation, macrophages secrete vesicles carrying RNA, protein, and lipids as a form of extracellular communication. In the vessel wall,…”
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PROGRESS IN OPERATIONS MANAGEMENT by GEOFFRION, ARTHUR M.

“…In this issue, Robert Hayes has written provocatively about the implications of the digital economy for Operations Management (om). Here I examine and…”
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RIPK1 Expression Associates With Inflammation in Early Atherosclerosis in Humans and Can Be Therapeutically Silenced to Reduce NF-κB Activation and Atherogenesis in Mice by Karunakaran, Denuja, Nguyen, My-Anh, Geoffrion, Michele, Vreeken, Dianne, Lister, Zachary, Cheng, Henry S., Otte, Nicola, Essebier, Patricia, Wyatt, Hailey, Kandiah, Joshua W., Jung, Richard, Alenghat, Francis J., Mompeon, Ana, Lee, Richard, Pan, Calvin, Gordon, Emma, Rasheed, Adil, Lusis, Aldons J., Liu, Peter, Matic, Ljubica Perisic, Hedin, Ulf, Fish, Jason E., Guo, Liang, Kolodgie, Frank, Virmani, Renu, van Gils, Janine M., Rayner, Katey J.

“…Chronic activation of the innate immune system drives inflammation and contributes directly to atherosclerosis. We previously showed that macrophages in the…”
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FW/SM: A Prototype Structured Modeling Environment by Geoffrion, Arthur M

“…A research prototype implementation has been evolving for several years in parallel with the vision, theory, language, and applicative aspects of structured…”
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The Formal Aspects of Structured Modeling by Geoffrion, Arthur M

“…Structured modeling is an approach to the development of a new generation of computer-based modeling environments. This paper, which is part of a series,…”
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Macrophage Mitochondrial Energy Status Regulates Cholesterol Efflux and Is Enhanced by Anti-miR33 in Atherosclerosis by Karunakaran, Denuja, Thrush, A Brianne, Nguyen, My-Anh, Richards, Laura, Geoffrion, Michele, Singaravelu, Ragunath, Ramphos, Eleni, Shangari, Prakriti, Ouimet, Mireille, Pezacki, John P, Moore, Kathryn J, Perisic, Ljubica, Maegdefessel, Lars, Hedin, Ulf, Harper, Mary-Ellen, Rayner, Katey J

“…RATIONALE:Therapeutically targeting macrophage reverse cholesterol transport is a promising approach to treat atherosclerosis. Macrophage energy metabolism can…”
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Forces, Trends, and Opportunities in MS/OR by Geoffrion, Arthur M

“…The purposes of this paper—a revised and extended version of the Omega Rho Lecture given at the November 1991 ORSA/TIMS Joint National Meeting—are to assess…”
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Autophagy is differentially regulated in leukocyte and nonleukocyte foam cells during atherosclerosis by Robichaud, S., Rasheed, A., Pietangelo, A., Kim, A. Doyoung, Boucher, D., Emerton, C., Vijithakumar, V., Gharibeh, L., Fairman, G., Mak, E., Nguyen, M.-A., Geoffrion, M., Wirka, R., Rayner, K., Ouimet, M.

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miR-223 Exerts Translational Control of Proatherogenic Genes in Macrophages by Nguyen, My-Anh, Hoang, Huy-Dung, Rasheed, Adil, Duchez, Anne-Claire, Wyatt, Hailey, Cottee, Mary Lynn, Graber, Tyson E., Susser, Leah, Robichaud, Sabrina, Berber, İbrahim, Geoffrion, Michele, Ouimet, Mireille, Kazan, Hilal, Maegdefessel, Lars, Mulvihill, Erin E., Alain, Tommy, Rayner, Katey J.

“…A significant burden of atherosclerotic disease is driven by inflammation. Recently, microRNAs (miRNAs) have emerged as important factors driving and…”
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Role of Extracellular MicroRNAs in Atherosclerosis by Nguyen, M, Karunakaran, D, Geoffrion, M, Rayner, K

“…Abstract only Atherosclerosis is a maladaptive inflammatory disease driven by the interplay between excess cholesterol accumulation in the arterial wall and…”
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IMPAIRED AUTOPHAGY IN ARTERIAL FOAM CELL POPULATIONS DURING ATHEROSCLEROSIS by Ouimet, M, Robichaud, S, Rasheed, A, Pietrangelo, A, Kim, A, Emerton, C, Vijithakumar, V, Gharibeh, L, Mak, E, Nguyen, M, Geoffrion, M, Wirka, R, Rayner, K

“…Atherosclerosis is characterized by an accumulation of foam cells within the arterial wall, resulting from excess cholesterol uptake and buildup of cytosolic…”
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Targeting macrophage necroptosis for therapeutic and diagnostic interventions in atherosclerosis by Karunakaran, Denuja, Geoffrion, Michele, Wei, Lihui, Gan, Wei, Richards, Laura, Shangari, Prakriti, DeKemp, Ella M, Beanlands, Rachelle A, Perisic, Ljubica, Maegdefessel, Lars, Hedin, Ulf, Sad, Subash, Guo, Liang, Kolodgie, Frank D, Virmani, Renu, Ruddy, Terrence, Rayner, Katey J

“…Atherosclerosis results from maladaptive inflammation driven primarily by macrophages, whose recruitment and proliferation drive plaque progression. In…”
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Indexing in Modeling Languages for Mathematical Programming by Geoffrion, Arthur M

“…Indexing structures are of fundamental importance to modeling languages for mathematical programming as a device for mathematical abstraction, and because they…”
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Macrophage mitochondrial energy status regulates cholesterol efflux and is enhanced by anti‐miR33 in atherosclerosis by Karunakaran, D, Thrush, B, Geoffrion, M, Ramphos, E, Nguygen, M, Shangari, P, Harper, M, Moore, K, Rayner, K

“…Abstract only…”
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Multicommodity Distribution System Design by Benders Decomposition by Geoffrion, A. M, Graves, G. W

“…A commonly occurring problem in distribution system design is the optimal location of intermediate distribution facilities between plants and customers. A…”
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Therapeutically inhibiting macrophage necroptosis reduces inflammation‐driven atherosclerosis and promotes plaque stability by Karunakaran, Denuja, Geoffrion, Michele, Lee, Richard, Wei, Lihui, Gan, Wei, Perisic, Ljubica, Maegdefessel, Lars, Hedin, Ulf, Sad, Subash, Guo, Liang, Kolodgie, Frank, Ruddy, Terrence, Virmani, Renu, Rayner, Katey

“…Abstract only Atherosclerosis is a maladaptive disease driven primarily by macrophages. As the atherosclerotic plaque progresses, inflammatory and macrophage…”
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