Search Results - "Genuth, Miriam A"

OligoTRAFTACs: A generalizable method for transcription factor degradation by Samarasinghe, Kusal T. G, An, Elvira, Genuth, Miriam A, Chu, Ling, Holley, Scott A, Crews, Craig M

“…Dysregulated transcription factors (TFs) that rewire gene expression circuitry are frequently identified as key players in disease. Although several TFs have…”
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Cell Migration: Recoiling from an Embrace by Genuth, Miriam A., Weiner, Orion D.

“…For proper spacing or rapid dispersion, some migratory cells are guided by repulsive collisions with their neighbors. A new study reveals that a surprising…”
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Mechanics as a Means of Information Propagation in Development by Genuth, Miriam A., Holley, Scott A.

“…New research demonstrates that mechanics can serve as a means of information propagation in developing embryos. Historically, the study of embryonic…”
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Chick cranial neural crest cells use progressive polarity refinement, not contact inhibition of locomotion, to guide their migration by Genuth, Miriam A., Allen, Christopher D.C., Mikawa, Takashi, Weiner, Orion D.

“…To move directionally, cells can bias the generation of protrusions or select among randomly generated protrusions. Here we use 3D two-photon imaging of chick…”
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Automated time-lapse data segmentation reveals in vivo cell state dynamics by Genuth, Miriam A, Kojima, Yasuhiro, Jülich, Dörthe, Kiryu, Hisanori, Holley, Scott A

“…Embryonic development proceeds as a series of orderly cell state transitions built upon noisy molecular processes. We defined gene expression and cell motion…”
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