Search Results - "Gentles, Lucy"

Characterization and drug sensitivity of a novel human ovarian clear cell carcinoma cell line genomically and phenotypically similar to the original tumor by Franklin, Miriam, Gentles, Lucy, Matheson, Elizabeth, Bown, Nick, Cross, Paul, Ralte, Angela, Gilkes‐Immeson, Connor, Bradbury, Alice, Zanjirband, Maryam, Lunec, John, Drew, Yvette, O'Donnell, Rachel, Curtin, Nicola J.

“…NUCOLL43 is a novel ovarian clear cell carcinoma (O‐CCC) cell line that arose from a primary culture of a patient's malignant ascites. The cells grow reliably…”
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Evaluating the potential of kinase inhibitors to suppress DNA repair and sensitise ovarian cancer cells to PARP inhibitors by Mukhopadhyay, Asima, Drew, Yvette, Matheson, Elizabeth, Salehan, Mo, Gentles, Lucy, Pachter, Jonathan A., Curtin, Nicola J.

“…[Display omitted] PARP inhibitors (PARPi) represent a major advance in the treatment of ovarian cancer associated with defects in homologous recombination DNA…”
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Genomic, Transcriptomic, and Functional Alterations in DNA Damage Response Pathways as Putative Biomarkers of Chemotherapy Response in Ovarian Cancer by Sharma Saha, Sweta, Gentles, Lucy, Bradbury, Alice, Brecht, Dominik, Robinson, Rebecca, O'Donnell, Rachel, Curtin, Nicola J, Drew, Yvette

“…Defective DNA damage response (DDR) pathways are enabling characteristics of cancers that not only can be exploited to specifically target cancer cells but…”
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An investigation of the effect of tissue ischaemia upon DNA damage protein markers in ovarian cancer by Tomassini, Sara, Gentles, Lucy, Kirk, Calum, Cross, Paul, Thomas, Huw, Wedge, Steve, Curtin, Nicola, O'Donnell, Rachel

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An investigation of the effect of tissue ischaemia upon DNA damage protein markers in ovarian cancer by Tomassini, Sara, Gentles, Lucy, Kirk, Calum, Cross, Paul, Thomas, Huw, Wedge, Steve, Curtin, Nicola, O'Donnell, Rachel

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Contribution of the Epithelial Sodium Channel to Chondrocyte Regulatory Volume Increase by Lewis, Rebecca, Gentles, Lucy, Barrett-Jolley, Richard

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Exploring the Frequency of Homologous Recombination DNA Repair Dysfunction in Multiple Cancer Types by Gentles, Lucy, Goranov, Bojidar, Matheson, Elizabeth, Herriott, Ashleigh, Kaufmann, Angelika, Hall, Sally, Mukhopadhyay, Asima, Drew, Yvette, Curtin, Nicola J, O'Donnell, Rachel L

“…Dysfunctional homologous recombination DNA repair (HRR), frequently due to BRCA mutations, is a determinant of sensitivity to platinum chemotherapy and…”
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