Search Results - "Gentle, Ian Edward"

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    The AML-associated K313 mutation enhances C/EBPα activity by leading to C/EBPα overexpression by Gentle, Ian Edward, Moelter, Isabel, Badr, Mohamed Tarek, Döhner, Konstanze, Lübbert, Michael, Häcker, Georg

    Published in Cell death & disease (05-07-2021)
    “…Mutations in the transcription factor C/EBPα are found in ~10% of all acute myeloid leukaemia (AML) cases but the contribution of these mutations to…”
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    Journal Article
  2. 2

    The deubiquitinase Usp27x as a novel regulator of cFLIPL protein expression and sensitizer to death-receptor-induced apoptosis by Dold, Manuel Nico, Ng, Xiulin, Alber, Claudia, Gentle, Ian Edward, Häcker, Georg, Weber, Arnim

    Published in Apoptosis (London) (01-02-2022)
    “…Death receptors are transmembrane proteins that can induce the activation of caspase-8 upon ligand binding, initiating apoptosis. Recent work has highlighted…”
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    Journal Article
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    The deubiquitinase Usp27x as a novel regulator of cFLIP L protein expression and sensitizer to death-receptor-induced apoptosis by Dold, Manuel Nico, Ng, Xiulin, Alber, Claudia, Gentle, Ian Edward, Häcker, Georg, Weber, Arnim

    Published in Apoptosis (London) (01-02-2022)
    “…Death receptors are transmembrane proteins that can induce the activation of caspase-8 upon ligand binding, initiating apoptosis. Recent work has highlighted…”
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    Journal Article
  5. 5

    TAK1 Is Required for Survival of Mouse Fibroblasts Treated with TRAIL, and Does So by NF-κB Dependent Induction of cFLIPL by Lluis, Josep Maria, Nachbur, Ulrich, Cook, Wendy Diane, Gentle, Ian Edward, Moujalled, Donia, Moulin, Maryline, Wong, Wendy Wei-Lynn, Khan, Nufail, Chau, Diep, Callus, Bernard Andrew, Vince, James Edward, Silke, John, Vaux, David Lawrence

    Published in PloS one (08-01-2010)
    “…Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is known as a “death ligand”—a member of the TNF superfamily that binds to receptors…”
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    Journal Article
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